The Library
Divergent presentation of anxiety in high-risk groups within the intellectual disability population
Tools
Groves, Laura, Moss, Joanna, Oliver, Chris, Royston, Rachel, Waite, Jane and Crawford, Hayley (2022) Divergent presentation of anxiety in high-risk groups within the intellectual disability population. Journal of Neurodevelopmental Disorders, 14 (1). 54. doi:10.1186/s11689-022-09462-w ISSN 1866-1955.
|
PDF
WRAP-Divergent-anxiety-high-risk-intellectual-disability-population-22.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1153Kb) | Preview |
Official URL: https://doi.org/10.1186/s11689-022-09462-w
Abstract
Background:
Anxiety symptomatology is common in individuals with intellectual disability (ID). Symptomatology includes both traditional Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) anxiety disorders and autism spectrum disorder (ASD)-related anxiety traits. Some genetic disorders such as Cornelia de Lange (CdLS) and fragile X syndromes (FXS) are at very high risk of anxiety and afford the opportunity to examine prevalence, profiles and associated person characteristics. However, prevalence and associated characteristics of anxiety in these high-risk groups remain poorly described and understood. The aim of the current study was to examine the prevalence and profile of DSM-5 and ASD-related anxiety symptomatology in individuals with CdLS and FXS and associated behavioural and cognitive characteristics.
Methods:
Questionnaires and interviews assessing DSM-5 and ASD-related anxiety were conducted with caregivers of individuals with CdLS (n = 49) and FXS (n = 36).
Results:
DSM-5 anxiety symptomatology was present in both groups with high co-morbidity across anxiety diagnoses. ASD-related anxiety was also prevalent with specific difficulties related to intolerance of uncertainty identified in both groups. Symptomatology was persistent over the lifespan for both groups. Anxiety type was partially associated with repetitive behaviour but not measures of overall ASD phenomenology in CdLS.
Conclusions:
DSM-5 and ASD-related anxiety are common in these high-risk syndromes associated with ID. Prospective syndrome specific presentations and associations, which may implicate specific underlying mechanisms, are discussed. Clinicians should be aware of the risk and difficulties involved in assessment of anxiety in individuals with ID, including atypical types, to ensure these individuals do not โmissโ diagnoses and support in general clinical practice.
Item Type: | Journal Article | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry | |||||||||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
|||||||||||||||
SWORD Depositor: | Library Publications Router | |||||||||||||||
Library of Congress Subject Headings (LCSH): | Anxiety disorders, Anxiety, People with mental disabilities, Genetic disorders -- Psychological aspects, Fragile X syndrome | |||||||||||||||
Journal or Publication Title: | Journal of Neurodevelopmental Disorders | |||||||||||||||
Publisher: | BioMed Central | |||||||||||||||
ISSN: | 1866-1955 | |||||||||||||||
Official Date: | 5 October 2022 | |||||||||||||||
Dates: |
|
|||||||||||||||
Volume: | 14 | |||||||||||||||
Number: | 1 | |||||||||||||||
Article Number: | 54 | |||||||||||||||
DOI: | 10.1186/s11689-022-09462-w | |||||||||||||||
Status: | Peer Reviewed | |||||||||||||||
Publication Status: | Published | |||||||||||||||
Reuse Statement (publisher, data, author rights): | ** From Springer Nature via Jisc Publications Router ** History: received 23-06-2021; accepted 12-09-2022; registration 13-09-2022; pub-electronic 05-10-2022; online 05-10-2022; pub-print 12-2022. ** Licence for this article: http://creativecommons.org/licenses/by/4.0/ ** Acknowledgements: Acknowledgements: We are extremely grateful to all the parents and carers who gave their time to contribute to and support this research. We would like to thank the Cornelia de Lange syndrome Foundation UK and Ireland and Fragile X Society for their support with this research and the recruitment of families. We would also like to thank Andrea Thomas, Dr Louise Bradley, Kira Moss and Dr Victoria Perry for assisting in the collection and inputting of data. | |||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||||||||
Date of first compliant deposit: | 21 October 2022 | |||||||||||||||
Date of first compliant Open Access: | 21 October 2022 | |||||||||||||||
RIOXX Funder/Project Grant: |
|
|||||||||||||||
Related URLs: |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year