The Library
The human posterior cingulate, retrosplenial, and medial parietal cortex effective connectome, and implications for memory and navigation
Tools
Rolls, Edmund T., Wirth, Sylvia, Deco, Gustavo, Huang, Chu‐Chung and Feng, Jianfeng (2023) The human posterior cingulate, retrosplenial, and medial parietal cortex effective connectome, and implications for memory and navigation. Human Brain Mapping, 44 (2). pp. 629-655. doi:10.1002/hbm.26089 ISSN 1065-9471.
|
PDF
WRAP-The-human-posterior-cingulate-retrosplenial-and-medial-parietal-cortex-effective-connectome-and-implications-for-memory-and-navigation-Rolls-2022.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (6Mb) | Preview |
Official URL: http://dx.doi.org/10.1002/hbm.26089
Abstract
The human posterior cingulate, retrosplenial, and medial parietal cortex are involved in memory and navigation. The functional anatomy underlying these cognitive functions was investigated by measuring the effective connectivity of these Posterior Cingulate Division (PCD) regions in the Human Connectome Project-MMP1 atlas in 171 HCP participants, and complemented with functional connectivity and diffusion tractography. First, the postero-ventral parts of the PCD (31pd, 31pv, 7m, d23ab, and v23ab) have effective connectivity with the temporal pole, inferior temporal visual cortex, cortex in the superior temporal sulcus implicated in auditory and semantic processing, with the reward-related vmPFC and pregenual anterior cingulate cortex, with the inferior parietal cortex, and with the hippocampal system. This connectivity implicates it in hippocampal episodic memory, providing routes for “what,” reward and semantic schema-related information to access the hippocampus. Second, the antero-dorsal parts of the PCD (especially 31a and 23d, PCV, and also RSC) have connectivity with early visual cortical areas including those that represent spatial scenes, with the superior parietal cortex, with the pregenual anterior cingulate cortex, and with the hippocampal system. This connectivity implicates it in the “where” component for hippocampal episodic memory and for spatial navigation. The dorsal–transitional–visual (DVT) and ProStriate regions where the retrosplenial scene area is located have connectivity from early visual cortical areas to the parahippocampal scene area, providing a ventromedial route for spatial scene information to reach the hippocampus. These connectivities provide important routes for “what,” reward, and “where” scene-related information for human hippocampal episodic memory and navigation. The midcingulate cortex provides a route from the anterior dorsal parts of the PCD and the supracallosal part of the anterior cingulate cortex to premotor regions.
Item Type: | Journal Article | |||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subjects: | Q Science > QM Human anatomy Q Science > QP Physiology |
|||||||||||||||||||||||||||||||||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Computer Science | |||||||||||||||||||||||||||||||||||||||
Library of Congress Subject Headings (LCSH): | Hippocampus (Brain), Memory, Cerebral cortex -- Research | |||||||||||||||||||||||||||||||||||||||
Journal or Publication Title: | Human Brain Mapping | |||||||||||||||||||||||||||||||||||||||
Publisher: | John Wiley and Sons | |||||||||||||||||||||||||||||||||||||||
ISSN: | 1065-9471 | |||||||||||||||||||||||||||||||||||||||
Official Date: | 1 February 2023 | |||||||||||||||||||||||||||||||||||||||
Dates: |
|
|||||||||||||||||||||||||||||||||||||||
Volume: | 44 | |||||||||||||||||||||||||||||||||||||||
Number: | 2 | |||||||||||||||||||||||||||||||||||||||
Number of Pages: | 27 | |||||||||||||||||||||||||||||||||||||||
Page Range: | pp. 629-655 | |||||||||||||||||||||||||||||||||||||||
DOI: | 10.1002/hbm.26089 | |||||||||||||||||||||||||||||||||||||||
Status: | Peer Reviewed | |||||||||||||||||||||||||||||||||||||||
Publication Status: | Published | |||||||||||||||||||||||||||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||||||||||||||||||||||||||||||||
Date of first compliant deposit: | 17 October 2022 | |||||||||||||||||||||||||||||||||||||||
Date of first compliant Open Access: | 18 October 2022 | |||||||||||||||||||||||||||||||||||||||
RIOXX Funder/Project Grant: |
|
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year