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Management of psoriatic arthritis in patients with comorbidities : an updated literature review informing the 2021 GRAPPA treatment recommendations
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Campanholo, Cristiano B., Maharaj, Ajesh B., Corp, Nadia, Bell, Stacie, Costa, Luisa, de Vlam, Kurt, Gullick, Nicola J., Khraishi, Majed, Kishimoto, Mitsumasa, Palmou-Fontana, Natalia, Reddy, Soumya, Scarpa, Raffaele, Vega, Luis, Duarte, Gleison Vieira, Zisman, Devy, van der Windt, Danielle A., Duruoz, Mehmet T. and Ogdie, Alexis (2023) Management of psoriatic arthritis in patients with comorbidities : an updated literature review informing the 2021 GRAPPA treatment recommendations. The Journal of Rheumatology, 50 (3). pp. 426-432. doi:10.3899/jrheum.220310 ISSN 0315-162X.
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Official URL: https://doi.org/10.3899/jrheum.220310
Abstract
Objective.
The 2021 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations provide an evidence-based guide for selecting therapy based on the individual's disease features. Beyond the disease features and associated conditions (eg, uveitis and inflammatory bowel disease), comorbidities play an important role in selecting therapy for an individual patient.
Methods.
We performed a systematic literature review. We examined the available evidence to inform treatment selection based on the presence or absence of comorbidities in psoriatic arthritis (PsA).
Results.
Common comorbidities in PsA that may affect treatment selection include presence of baseline cardiovascular disease (CVD) or high risk for CVD, obesity and metabolic syndrome, liver disease, mood disorders, including depression in particular, chronic infections, malignancies, osteoporosis, and fibromyalgia and/or central sensitization.
Conclusion.
Comorbidities may influence both the effectiveness of a given therapy but also the potential for adverse events. It is important to assess for the presence of comorbidities prior to therapy selection.
Item Type: | Journal Article | ||||||||
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Subjects: | R Medicine > RC Internal medicine | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||
SWORD Depositor: | Library Publications Router | ||||||||
Library of Congress Subject Headings (LCSH): | Psoriatic arthritis, Psoriatic arthritis -- Treatment, Comorbidity | ||||||||
Journal or Publication Title: | The Journal of Rheumatology | ||||||||
Publisher: | Journal of Rheumatology Publishing Co. Ltd. | ||||||||
ISSN: | 0315-162X | ||||||||
Official Date: | 1 March 2023 | ||||||||
Dates: |
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Volume: | 50 | ||||||||
Number: | 3 | ||||||||
Page Range: | pp. 426-432 | ||||||||
DOI: | 10.3899/jrheum.220310 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Copyright Holders: | The Journal of Rheumatology | ||||||||
Date of first compliant deposit: | 15 February 2023 | ||||||||
Date of first compliant Open Access: | 15 February 2023 |
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