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Contact lens-based microchannel rings for detecting ocular hypertension
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Alqurashi, Yousef, Elsherif, Mohamed, Moreddu, Rosalia, Cieslak, Magdalena, Dhaliwal, Hemeth, Essa, Khamis and Butt, Haider (2022) Contact lens-based microchannel rings for detecting ocular hypertension. Applied Sciences, 12 (20). 10661. doi:10.3390/app122010661 ISSN 2076-3417.
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WRAP-Contact-lens-based-microchannel-rings-for-detecting-ocular-hypertension-Ciesalk-2022.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (2284Kb) | Preview |
Official URL: http://dx.doi.org/10.3390/app122010661
Abstract
Glaucoma is a major cause of irreversible blindness worldwide. The most acknowledged biomarker to diagnose and monitor glaucoma progression is intraocular pressure (IOP). Gold standard techniques for IOP monitoring are invasive, uncomfortable, and require visiting a clinic. In addition, most methods only provide a single snapshot on widely varying parameters. On the other hand, contact lenses have attracted particular interest to be used as continuous monitoring platforms to incorporate sensors, drugs, and more. Here, commercial contact lenses were laser-processed to be capable of detecting IOP variations in the physiological range. Three ring-couples with interspaces of 1.0, 1.5, and 2.0 mm were engraved on three soft contact lenses separately by using a carbon dioxide laser. The IOP/pressure variations induced repeatable changes in the ring-couple interspace which acted as a smartphone-readable pressure sensor. The processed contact lenses may be a potential candidate toward IOP monitoring at point-of-care settings.
| Item Type: | Journal Article | ||||||||||||
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| Subjects: | R Medicine > RE Ophthalmology T Technology > TA Engineering (General). Civil engineering (General) |
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| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group) | ||||||||||||
| Library of Congress Subject Headings (LCSH): | Contact lenses, Glaucoma, Intraocular pressure, Carbon dioxide lasers | ||||||||||||
| Journal or Publication Title: | Applied Sciences | ||||||||||||
| Publisher: | MDPI | ||||||||||||
| ISSN: | 2076-3417 | ||||||||||||
| Official Date: | 21 October 2022 | ||||||||||||
| Dates: |
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| Volume: | 12 | ||||||||||||
| Number: | 20 | ||||||||||||
| Number of Pages: | 9 | ||||||||||||
| Article Number: | 10661 | ||||||||||||
| DOI: | 10.3390/app122010661 | ||||||||||||
| Status: | Peer Reviewed | ||||||||||||
| Publication Status: | Published | ||||||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||
| Date of first compliant deposit: | 12 December 2022 | ||||||||||||
| Date of first compliant Open Access: | 12 December 2022 | ||||||||||||
| RIOXX Funder/Project Grant: |
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