Functional ecology of bacteriophages in the environment

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Abstract

Bacteriophages are as ubiquitous as their bacterial hosts and often more abundant. Understanding how bacteriophages control their bacterial host populations requires a number of different approaches. Bacteriophages can control bacterial populations through lysis, drive evolution of bacterial immunity systems through infection, provide a conduit for horizontal gene transfer and alter host metabolism by carriage of auxiliary metabolic genes. Understanding and quantifying how bacteriophages drive these processes, requires both technological developments to take measurements in situ, and laboratory-based studies to understand mechanisms. Technological advances have allowed quantification of the number of infected cells in situ, revealing far-lower levels than expected. Understanding how observations in laboratory conditions relate to what occurs in the environment, and experimental confirmation of the predicted function of phage genes from observations in environmental omics data, remains challenging.

Item Type: Journal Article
Subjects: Q Science > QR Microbiology
Divisions: Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
SWORD Depositor: Library Publications Router
Library of Congress Subject Headings (LCSH): Bacteriophages
Journal or Publication Title: Current Opinion in Microbiology
Publisher: Elsevier Ltd
ISSN: 1369-5274
Official Date: February 2023
Dates:
Date
Event
February 2023
Published
10 December 2022
Available
10 December 2022
Accepted
Volume: 71
Article Number: 102245
DOI: 10.1016/j.mib.2022.102245
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons open licence)
Date of first compliant deposit: 3 January 2023
Date of first compliant Open Access: 4 January 2023
URI: https://wrap.warwick.ac.uk/171854/

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