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Diffusive molecular communication with a spheroidal receiver for organ-on-chip systems
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Arjmandi, Hamidreza, Zoofaghari, Mohamad, Rezaei, Mitra, Kanebratt, Kajsa, Vilen, Liisa, Janzén, David, Gennemark, Peter and Noel, Adam (2023) Diffusive molecular communication with a spheroidal receiver for organ-on-chip systems. In: IEEE International Conference on Communications, Rome, Italy, 28 May - 01 Jun 2023. Published in: IEEE International Conference on Communications ISSN 1550-3607. (In Press)
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Abstract
Realistic models of the components and processes are required for molecular communication (MC) systems. In this paper, a spheroidal receiver structure is proposed for MC that is inspired by the 3D cell cultures known as spheroids being widely used in organ-on-chip systems. A simple diffusive MC system is considered where the spheroidal receiver and a point source transmitter are in an unbounded fluid environment. The spheroidal receiver is modeled as a porous medium for diffusive signaling molecules, then its boundary conditions and effective diffusion coefficient are characterized. It is revealed that the spheroid amplifies the diffusion signal, but also disperses the signal which reduces the information communication rate. Furthermore, we analytically formulate and derive the concentration Green’s function inside and outside the spheroid in terms of infinite series-forms that are confirmed by a particle-based simulator (PBS).
Item Type: | Conference Item (Paper) | ||||||
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Subjects: | Q Science > QC Physics T Technology > T Technology (General) T Technology > TK Electrical engineering. Electronics Nuclear engineering |
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Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||||
Library of Congress Subject Headings (LCSH): | Molecular communication (Telecommunication) , Signal processing , Nanotechnology, Diffusion , Computational biology | ||||||
Journal or Publication Title: | IEEE International Conference on Communications | ||||||
Publisher: | IEEE | ||||||
ISSN: | 1550-3607 | ||||||
Official Date: | 2023 | ||||||
Dates: |
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Status: | Peer Reviewed | ||||||
Publication Status: | In Press | ||||||
Reuse Statement (publisher, data, author rights): | © 2023 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. | ||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||
Date of first compliant deposit: | 30 January 2023 | ||||||
Date of first compliant Open Access: | 30 January 2023 | ||||||
RIOXX Funder/Project Grant: |
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Conference Paper Type: | Paper | ||||||
Title of Event: | IEEE International Conference on Communications | ||||||
Type of Event: | Conference | ||||||
Location of Event: | Rome, Italy | ||||||
Date(s) of Event: | 28 May - 01 Jun 2023 | ||||||
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