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Weak convergence of non-neutral genealogies to Kingman's coalescent

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Brown, Suzie, Jenkins, Paul, Johansen, Adam M. and Koskela, Jere (2023) Weak convergence of non-neutral genealogies to Kingman's coalescent. Stochastic Processes and their Applications, 162 . pp. 76-105. doi:10.1016/j.spa.2023.04.016 ISSN 0304-4149.

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Official URL: https://doi.org/10.1016/j.spa.2023.04.016

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Abstract

Interacting particle systems undergoing repeated mutation and selection steps model genetic evolution, and also describe a broad class of sequential Monte Carlo methods. The genealogical tree embedded into the system is important in both applications. Under neutrality, when fitnesses of particles are independent from those of their parents, rescaled genealogies are known to converge to Kingman’s coalescent. Recent work has established convergence under non-neutrality, but only for finite-dimensional distributions. We prove weak convergence of non-neutral genealogies on the space of càdlàg paths under standard assumptions, enabling analysis of the whole genealogical tree.

Item Type: Journal Article
Subjects: Q Science > QA Mathematics
Q Science > QH Natural history > QH426 Genetics
Divisions: Faculty of Science, Engineering and Medicine > Science > Statistics
Library of Congress Subject Headings (LCSH): Population genetics -- Mathematical models, Statistical physics
Journal or Publication Title: Stochastic Processes and their Applications
Publisher: Elsevier Science BV
ISSN: 0304-4149
Official Date: August 2023
Dates:
DateEvent
August 2023Published
25 April 2023Available
20 April 2023Accepted
Volume: 162
Page Range: pp. 76-105
DOI: 10.1016/j.spa.2023.04.016
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Description:

This work was supported by the Engineering and Physical Sciences Research Council, the Medical Research Council, the Alan Turing Institute, and the Alan Turing Institute-Lloyd’s Register Foundation Programme on Data-centric Engineering, under grant numbers EP/L016710/1, EP/N510129/1, EP/R034710/1, EP/R044732/1, EP/T004134/1 and EP/V049208/1.

Date of first compliant deposit: 21 April 2023
Date of first compliant Open Access: 26 May 2023
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
EP/L016710/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
EP/N510129/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
EP/R034710/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
EP/R044732/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
EP/T004134/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
EP/V049208/1[EPSRC] Engineering and Physical Sciences Research Councilhttp://dx.doi.org/10.13039/501100000266
UNSPECIFIED[MRC] Medical Research Councilhttp://dx.doi.org/10.13039/501100000265
UNSPECIFIEDAlan Turing Institutehttp://dx.doi.org/10.13039/100012338
UNSPECIFIEDLloyd's Register Foundationhttp://dx.doi.org/10.13039/100008885
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