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Metabolic changes following intermittent fasting : a rapid review of systematic reviews

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Lange, Maria, Coffey, A. A., Coleman, P. C., Barber, Thomas M., Van Rens, Thijs, Oyebode, Oyinlola and Hanson, Petra (2023) Metabolic changes following intermittent fasting : a rapid review of systematic reviews. Journal of Human Nutrition and Dietetics . doi:10.1111/jhn.13253 ISSN 0952-3871. (In Press)

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Official URL: https://doi.org/10.1111/jhn.13253

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Abstract

Background
The prevalence of obesity is rising globally and effective strategies to treat obesity are needed. Intermittent fasting, a dietary intervention for weight management, has received growing interest from the general public, as well as healthcare professionals, as a form of lifestyle intervention.

Methods
We executed a rapid review using PUBMED database to identify systematic reviews which examined the impact of intermittent fasting on metabolic indices, published between 2011 and 2022.

Results
Intermittent fasting leads to weight loss of a similar magnitude to continuous energy restriction. Most of the evidence shows that intermittent fasting leads to greater fat loss as measured by fat mass (kg) or body fat percentage when compared with ad libitum diet, but fat loss attained during intermittent fasting is not significantly different to continuous energy restriction although recent evidence shows intermittent fasting to be superior. There is mixed evidence for the impact of intermittent fasting on insulin resistance, fasting glucose and lipid profile. Some studies focused on populations of Muslim people, which showed that Ramadan fasting may lead to weight loss and improvement of metabolic parameters during fasting, but the effects are reversed when fasting is finished.

Item Type: Journal Article
Divisions: Faculty of Arts > School for Cross-faculty Studies
Faculty of Social Sciences > Economics
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016)
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET)
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: Journal of Human Nutrition and Dietetics
Publisher: Wiley-Blackwell Publishing Ltd.
ISSN: 0952-3871
Official Date: 2023
Dates:
DateEvent
2023Published
2 October 2023Available
22 September 2023Accepted
DOI: 10.1111/jhn.13253
Status: Peer Reviewed
Publication Status: In Press
Reuse Statement (publisher, data, author rights): This is the peer reviewed version of the following article:Lange, M.G., Coffey, A.A., Coleman, P.C., Barber, T.M., Van Rens, T., Oyebode, O., Abbott, S. and Hanson, P. (2023), Metabolic changes following intermittent fasting: A rapid review of systematic reviews. J Hum Nutr Diet., which has been published in final form at https://doi.org/10.1111/jhn.13253. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 13 October 2023
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