The Library
Glycosidase-catalysed oligosaccharide synthesis of di-, tri- and tetra-saccharides using the N-acetylhexosaminidase from Aspergillus oryzae and the beta-galactosidase from Bacillus circulans
Tools
UNSPECIFIED (1996) Glycosidase-catalysed oligosaccharide synthesis of di-, tri- and tetra-saccharides using the N-acetylhexosaminidase from Aspergillus oryzae and the beta-galactosidase from Bacillus circulans. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (16). pp. 1921-1926. ISSN 0300-922X.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Abstract
The N-acetylhexosaminidase from Aspergillus oryzae catalyse transfer of N-acetylglucosaminyl and N-acetylgalactosaminyl residues selectively on to the 6-OH group of N-acetylgalactosamine to give the corresponding (1-->6)-linked disaccharides 3 and 6 in 26 and 38% yield, respectively, The disaccharide beta-D-GlcpNAc-(1-->6)-beta-D-GalpNAc 3 thus synthesized acts as acceptor for transfer of a beta-D-galactosyl residue from the corresponding p-nitrophenyl glycoside on to the 4-OH group of the non-reducing unit to give the ovarian cyst fluid mucin fragment beta-D-Galp-(1-->4)-beta-GlcpNAc-(1-->6)-D-GalpNAc 8 in 48% yield together with the tetrasaccharide beta-D-Galp-(1-->4)-beta-D-Galp-(1-->4)-beta-D-GlcpNAc-(1-->6)-D-GalpNAc 9 in 7% yield, With lactose as acceptor, the trisaccharide beta-D-Galp-(1-->4)-beta-D-Galp-(1-->4)-D-Glcp 12, a growth factor for human intestinal bifidobacteria, is produced in 52% yield.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry | ||||
Journal or Publication Title: | JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | ||||
Publisher: | ROYAL SOC CHEMISTRY | ||||
ISSN: | 0300-922X | ||||
Official Date: | 21 August 1996 | ||||
Dates: |
|
||||
Number: | 16 | ||||
Number of Pages: | 6 | ||||
Page Range: | pp. 1921-1926 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |