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Carbohydrate carbamate coated onto microporous silica: Application to chiral analysis of commercial pharmaceutical drugs
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UNSPECIFIED (1996) Carbohydrate carbamate coated onto microporous silica: Application to chiral analysis of commercial pharmaceutical drugs. In: 6th International Symposium on Chiral Discrimination, ST LOUIS, MO, APR 26-28, 1995. Published in: CHIRALITY, 8 (1). pp. 143-146. ISSN 0899-0042.
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Abstract
The enantioselectivity of a series of chiral analytes was examined on tris-(3,5-dimethylphenyl carbamate) coated onto microporous APS-silica. The effects of the nature of the carbohydrate, the weight ratio of carbamate/support and the type of alcohol present in the mobile phase were investigated. Among the chiral analytes examined, propanolol showed an extremely good resolution. The resolution of tetramisole was optimized and the method developed was shown to be suitable for analysis of the drug in commercial tablets and in a suspension. (C) 1996 Wiley-Liss, Inc.
Item Type: | Conference Item (UNSPECIFIED) | ||||
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Subjects: | Q Science > QD Chemistry R Medicine > RS Pharmacy and materia medica |
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Journal or Publication Title: | CHIRALITY | ||||
Publisher: | WILEY-LISS | ||||
ISSN: | 0899-0042 | ||||
Official Date: | 1996 | ||||
Dates: |
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Volume: | 8 | ||||
Number: | 1 | ||||
Number of Pages: | 4 | ||||
Page Range: | pp. 143-146 | ||||
Publication Status: | Published | ||||
Title of Event: | 6th International Symposium on Chiral Discrimination | ||||
Location of Event: | ST LOUIS, MO | ||||
Date(s) of Event: | APR 26-28, 1995 |
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