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Characterisation of the interaction between the nucleoprotein and phosphoprotein of pneumonia virus of mice
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UNSPECIFIED (1995) Characterisation of the interaction between the nucleoprotein and phosphoprotein of pneumonia virus of mice. VIRUS RESEARCH, 39 (2-3). pp. 221-235. ISSN 0168-1702.
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Abstract
A protein blotting technique was used to study the interaction occurring between the pneumonia virus of mice N protein and other PVM encoded proteins expressed in infected cells. Measurement of the degree of binding indicated that the N protein specifically interacted only with the full-length 39 kDa P protein in infected cells. Truncated N-related proteins were synthesised in vitro and incubated with filter-bound full-length and truncated P proteins. The data suggested that many regions of the N protein are cooperatively involved in the binding process. It was also determined that both the amino and the carboxyl-terminal regions of the PVM P protein were essential for binding to N protein.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QR Microbiology > QR355 Virology | ||||
Journal or Publication Title: | VIRUS RESEARCH | ||||
Publisher: | ELSEVIER SCIENCE BV | ||||
ISSN: | 0168-1702 | ||||
Official Date: | December 1995 | ||||
Dates: |
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Volume: | 39 | ||||
Number: | 2-3 | ||||
Number of Pages: | 15 | ||||
Page Range: | pp. 221-235 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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