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THE NUCLEOTIDE-SEQUENCES OF INTERGENIC REGIONS BETWEEN 9 GENES OF PNEUMONIA VIRUS OF MICE ESTABLISH THE PHYSICAL ORDER OF THESE GENES IN THE VIRAL GENOME
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UNSPECIFIED (1991) THE NUCLEOTIDE-SEQUENCES OF INTERGENIC REGIONS BETWEEN 9 GENES OF PNEUMONIA VIRUS OF MICE ESTABLISH THE PHYSICAL ORDER OF THESE GENES IN THE VIRAL GENOME. VIRUS RESEARCH, 18 (2-3). pp. 263-270. ISSN 0168-1702.
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Abstract
We have cloned eight intergenic regions from the Pneumovirus pneumonia virus of mice that link the nine small and medium sized genes previously described (Chambers et al., 1990). The nucleotide sequences of the clones confirm the locations of these genes and their mRNA transcripts in the viral genome. The intergenic regions vary in size from 2-56 nucleotides and show only faint homology to each other or to their analogues in respiratory syncytial virus. Sequence alignments suggest that the location of the transcriptional start site for the mRNA encoding the major nucleocapsid protein of pneumonia virus of mice and respiratory syncytial virus may have altered during virus evolution by gain or loss of a transcriptional start signal.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QR Microbiology > QR355 Virology | ||||
Journal or Publication Title: | VIRUS RESEARCH | ||||
Publisher: | ELSEVIER SCIENCE BV | ||||
ISSN: | 0168-1702 | ||||
Official Date: | March 1991 | ||||
Dates: |
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Volume: | 18 | ||||
Number: | 2-3 | ||||
Number of Pages: | 8 | ||||
Page Range: | pp. 263-270 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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