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Screening for osteoporosis in anorexia nervosa: Prevalence and predictors of reduced bone mineral density
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Winston, Anthony P., Alwazeer, Ahmed E. F. and Bankart, Michael J. G. (2008) Screening for osteoporosis in anorexia nervosa: Prevalence and predictors of reduced bone mineral density. International Journal of Eating Disorders, Volume 41 (Number 3). pp. 284-287. doi:10.1002/eat.20501 ISSN 0276-3478.
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Official URL: http://dx.doi.org/10.1002/eat.20501
Abstract
Objective: Decreased bone mineral density (BMD) in anorexia nervosa (AN) can be detected easily by dual-energy Xray absorptiometry (DXA). This study was designed to assess the prevalence of osteoporosis and osteopenia in AN, identify predictors, and determine the diagnostic yield of screening with DXA.
Method: DXA was used to screen 59 unselected adult patients with a history of AN.
Results: Osteoporosis was identified in 18 patients (31%) and osteopenia in 30 (51%). The spine had a lower mean T-score than either the hip or femur. BMI significantly predicted T-score (p = 0.0006) and the odds of having osteoporosis (p = 0.0188). There was a significant association between use of oestrogens and the presence of osteoporosis or osteopenia (p = 0.0491). There was no significant association between duration of AN and T-score. A duration of AN of less than 1 year was found in 12% of those with osteoporosis.
Conclusion: BMI is a strong predictor of BMD in AN. DXA is an effective screening tool and should probably be offered routinely. (c) 2008 by Wiley Periodicals, Inc.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
Library of Congress Subject Headings (LCSH): | Osteoporosis -- Diagnosis, Anorexia nervosa -- Patients -- Medical examination, Medical screening, Dual-energy X-ray absorptiometry, Bone densitometry | ||||
Journal or Publication Title: | International Journal of Eating Disorders | ||||
Publisher: | John Wiley & Sons | ||||
ISSN: | 0276-3478 | ||||
Official Date: | April 2008 | ||||
Dates: |
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Volume: | Volume 41 | ||||
Number: | Number 3 | ||||
Number of Pages: | 4 | ||||
Page Range: | pp. 284-287 | ||||
DOI: | 10.1002/eat.20501 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
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