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A photoimmobilisation strategy that maximises exploration of chemical space in small molecule affinity selection and target discovery
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Dilly, Suzanne J., Bell, Matthew J., Clark, Andrew J., Marsh, Andrew, Napier, R. (Richard), Sergeant, Martin J., Thompson, Andrew J. and Taylor, Paul C. (2007) A photoimmobilisation strategy that maximises exploration of chemical space in small molecule affinity selection and target discovery. Chemical Communications (Number 27). pp. 2808-2810. doi:10.1039/b704271j ISSN 1359-7345.
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Official URL: http://dx.doi.org/10.1039/b704271j
Abstract
We show that the use of multiple photochemistries is necessary to ensure diverse immobilisation of small molecules for binding of polypeptides using phage display and antibody libraries.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) > Warwick HRI (2004-2010) |
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Journal or Publication Title: | Chemical Communications | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 1359-7345 | ||||
Official Date: | 2007 | ||||
Dates: |
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Number: | Number 27 | ||||
Number of Pages: | 3 | ||||
Page Range: | pp. 2808-2810 | ||||
DOI: | 10.1039/b704271j | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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