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The tatC gene cluster is essential for viability in halophilic archaea
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UNSPECIFIED (2006) The tatC gene cluster is essential for viability in halophilic archaea. FEMS MICROBIOLOGY LETTERS, 256 (1). pp. 44-49. doi:10.1111/j.1574-6968.2006.00107.x ISSN 0378-1097.
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Official URL: http://dx.doi.org/10.1111/j.1574-6968.2006.00107.x
Abstract
In prokaryotes the twin-arginine translocase (Tat) is a unique transport system for the export of folded proteins. The Tat pathway is usually involved in the export of a small proportion of extracytoplasmic proteins. An exception is found in halophilic archaea, in which the majority of secretory proteins have been predicted to be Tat-dependent. All haloarchaea analysed to date contain two genes encoding homologues of the Tat-component TatC. In all of these cases both genes are located adjacently on the chromosome, indicating that they form a functional unit. We show that this gene cluster is essential for viability in haloarchaea, which is in complete contrast to all other prokaryotes that have been tested thus far.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QR Microbiology | ||||
Journal or Publication Title: | FEMS MICROBIOLOGY LETTERS | ||||
Publisher: | BLACKWELL PUBLISHING | ||||
ISSN: | 0378-1097 | ||||
Official Date: | March 2006 | ||||
Dates: |
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Volume: | 256 | ||||
Number: | 1 | ||||
Number of Pages: | 6 | ||||
Page Range: | pp. 44-49 | ||||
DOI: | 10.1111/j.1574-6968.2006.00107.x | ||||
Publication Status: | Published |
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