Munywoki, Patrick, Hamid, Fauzat, Mutunga, Martin, Welch, Steve, Cane, Patricia and Nokes, D. James (2011) Improved detection of respiratory viruses in pediatric outpatients with acute respiratory illness by real-time PCR using nasopharyngeal flocked swabs. Journal of Clinical Microbiology, Vol.49 (No.9). pp. 3365-3367. doi:10.1128/JCM.02231-10

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Abstract

Detection of respiratory viruses by realtime multiplexed PCR (M-PCR) and of RSV by M-PCR and immunofluorescence(IF) was evaluated using specimens collected by
nasopharyngeal flocked swab(NFS) and nasal wash(NW). In children with mild respiratory
illness, NFS collection was superior to NW collection for detection of viruses by M-PCR
(sensitivity 89.6% vs 79.2%, P=0.0043). NFS collection was non-inferior to NW collection in
detecting RSV by IF.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine R Medicine > RJ Pediatrics
Divisions:	Faculty of Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH):	Respiratory infections in children -- Diagnosis, Polymerase chain reaction, Diagnostic specimens -- Methodology
Journal or Publication Title:	Journal of Clinical Microbiology
Publisher:	American Society for Microbiology
ISSN:	0095-1137
Official Date:	20 July 2011
Dates:	Date Event 20 July 2011 Published
Date of first compliant deposit:	18 December 2015
Volume:	Vol.49
Number:	No.9
Page Range:	pp. 3365-3367
DOI:	10.1128/JCM.02231-10
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Bill & Melinda Gates Foundation, Wellcome Trust (London, England)
Grant number:	076278 (WT), 090853 (WT)

Data sourced from Thomson Reuters' Web of Knowledge

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