Hill, Margaret J., Metcalfe, David and McTernan, P. G. (Philip G.) (2009) Obesity and diabetes : lipids, 'nowhere to run to'. Clinical Science, Vol.116 (No.2). pp. 113-123. doi:10.1042/CS20080050 ISSN 0143-5221.

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Abstract

Although specific pathogenic entities contributing to diabetic risk, such as central adiposity, ectopic fat accumulation, hyperlipidaemia and inflammation, are well-characterized, the response of cellular systems to such insults are less well understood. This short review highlights the effect of increasing fat mass on ectopic fat accumulation, the role of triacylglycerols (triglycerides) in Type 2 diabetes mellitus and cardiovascular disease pathogenesis, and selected current therapeutic strategies used to ameliorate these risk factors.

Item Type:	Journal Article
Subjects:	R Medicine > R Medicine (General)
Divisions:	Other > Institute of Advanced Teaching & Learning Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title:	Clinical Science
Publisher:	Portland Press
ISSN:	0143-5221
Official Date:	2009
Dates:	Date Event 2009 Published
Volume:	Vol.116
Number:	No.2
Page Range:	pp. 113-123
DOI:	10.1042/CS20080050
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access

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