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Obesity and diabetes : lipids, 'nowhere to run to'
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Hill, Margaret J., Metcalfe, David and McTernan, P. G. (Philip G.) (2009) Obesity and diabetes : lipids, 'nowhere to run to'. Clinical Science, Vol.116 (No.2). pp. 113-123. doi:10.1042/CS20080050 ISSN 0143-5221.
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Official URL: http://dx.doi.org/10.1042/CS20080050
Abstract
Although specific pathogenic entities contributing to diabetic risk, such as central adiposity, ectopic fat accumulation, hyperlipidaemia and inflammation, are well-characterized, the response of cellular systems to such insults are less well understood. This short review highlights the effect of increasing fat mass on ectopic fat accumulation, the role of triacylglycerols (triglycerides) in Type 2 diabetes mellitus and cardiovascular disease pathogenesis, and selected current therapeutic strategies used to ameliorate these risk factors.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > R Medicine (General) | ||||
Divisions: | Other > Institute of Advanced Teaching & Learning Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Clinical Science | ||||
Publisher: | Portland Press | ||||
ISSN: | 0143-5221 | ||||
Official Date: | 2009 | ||||
Dates: |
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Volume: | Vol.116 | ||||
Number: | No.2 | ||||
Page Range: | pp. 113-123 | ||||
DOI: | 10.1042/CS20080050 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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