Rønne, Filip Munch, Dau, Torsten, Harte, James M. and Elberling, Claus (2011) Modelling the level-dependent latency of the auditory brainstem response. In: Forum Acusticum 2011, Aalborg, Denmark, 27 Jun - 1 Jul 2011. Published in: Proceedings of Forum Acusticum 2011 2633 -2638 . ISSN 9788469415207.

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Abstract

Auditory brainstem responses (ABR) are used for both clinical and research purposes to objectively assess human hearing. A prominent feature of the transient evoked ABR is the level-dependent latency of the distinct peaks in its waveform. The latency of the most prominent peak, wave-V, is about 8 ms at a peak equivalent sound pressure level of 55 dB, and reduces for increasing level by approximately 1 ms / 20 dB. A classical explanation for this finding asserts that an increasing stimulus levels lead to a broadened excitation pattern on the basilar membrane. This results in further activation of the basal regions of the cochlea. Given the physical properties of the basilar membrane, increased basal activation is believed to cause a decreasing ABR latency. An Auditory Nerve (AN) model and the Dual Resonance Non-Linearity (DRNL) filter model are considered as separate front-end cochlear models to simulate ABRs. Even though both models incorporate level-dependent tuning and synapse adaptation, and thus theoretically should be capable of simulating level-dependent latencies, both models under-predict the latencies. The failure to produce accurate simulations suggests, that the level-depending tuning in the models is not accurately modelled. The level dependency of the basilar membrane filter tuning in humans is not well described in the literature and could therefore cause the modelling difficulties.

Item Type:	Conference Item (Paper)
Subjects:	R Medicine > RF Otorhinolaryngology T Technology > TA Engineering (General). Civil engineering (General)
Divisions:	Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group)
Journal or Publication Title:	Proceedings of Forum Acusticum 2011
Publisher:	European Acoustics Association
ISSN:	9788469415207
Official Date:	2011
Dates:	Date Event 2011 Published
Page Range:	2633 -2638
Status:	Not Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Conference Paper Type:	Paper
Title of Event:	Forum Acusticum 2011
Type of Event:	Conference
Location of Event:	Aalborg, Denmark
Date(s) of Event:	27 Jun - 1 Jul 2011
Related URLs:	Other Repository

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