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Annelation of perfluorinated heteroaromatic systems by 1,3-dicarbonyl derivatives
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Cartwright, Matthew W., Parks, Emma L., Pattison, Graham, Slater, Rachel, Sandford, Graham, Wilson, Ian, Yufit, Dmitrii S., Howard, Judith A.K., Christopher, John A. and Miller, David D. (2010) Annelation of perfluorinated heteroaromatic systems by 1,3-dicarbonyl derivatives. Tetrahedron, Vol.66 (No.17). pp. 3222-3227. doi:10.1016/j.tet.2010.02.083 ISSN 0040-4020 .
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Official URL: http://dx.doi.org/10.1016/j.tet.2010.02.083
Abstract
Reactions of various perfluorinated heteroaromatic substrates such as tetrafluoro-4-cyanopyridine, tetrafluoropyrazine and tetrafluoropyridazine with 1,3-dicarbonyl systems gave corresponding [5,6]-ring fused furo derivatives. Subsequent reactions of the [5,6] bicyclic scaffolds with nucleophiles gave some highly functionalised heteroaromatic systems.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Journal or Publication Title: | Tetrahedron | ||||
Publisher: | Pergamon | ||||
ISSN: | 0040-4020 | ||||
Official Date: | 2010 | ||||
Dates: |
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Volume: | Vol.66 | ||||
Number: | No.17 | ||||
Page Range: | pp. 3222-3227 | ||||
DOI: | 10.1016/j.tet.2010.02.083 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | EPSRC, GlaxoSmithKline |
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