The Library
Role of adipokines in cardiovascular disease
Tools
Tools
Tools
Mattu, Harman and Randeva, Harpal S. (2013) Role of adipokines in cardiovascular disease. Journal of Endocrinology, Vol.216 (No.1). T17-T36. doi:10.1530/JOE-12-0232 ISSN 0022-0795.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1530/JOE-12-0232
Abstract
The discovery of leptin in 1994 sparked dramatic new interest in the study of white adipose tissue. It is now recognised to be a metabolically active endocrine organ, producing important chemical messengers – adipokines and cytokines (adipocytokines). The search for new adipocytokines or adipokines gained added fervour with the prospect of the reconciliation between cardiovascular diseases (CVDs), obesity and metabolic syndrome.
The role these new chemical messengers play in inflammation, satiety, metabolism and cardiac function has paved the way for new research and theories examining the effects they have on (in this case) CVD. Adipokines are involved in a ‘good–bad’, yin–yang homoeostatic balance whereby there are substantial benefits: cardioprotection, promoting endothelial
function, angiogenesis and reducing hypertension, atherosclerosis and inflammation. The flip side may show contrasting, detrimental effects in aggravating these cardiac parameters
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||
| Journal or Publication Title: | Journal of Endocrinology | ||||
| Publisher: | Society for Endocrinology | ||||
| ISSN: | 0022-0795 | ||||
| Official Date: | 2013 | ||||
| Dates: |
|
||||
| Volume: | Vol.216 | ||||
| Number: | No.1 | ||||
| Page Range: | T17-T36 | ||||
| DOI: | 10.1530/JOE-12-0232 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Open Access (Creative Commons) |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
