The Library
LD spectroscopy of natural and synthetic biomaterials
Tools
Hicks, Matthew R., Kowalski, Jarosav and Rodger, Alison (2010) LD spectroscopy of natural and synthetic biomaterials. Chemical Society Reviews, Vol.39 (No.9). pp. 3380-3393. doi:10.1039/b912917k
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1039/b912917k
Abstract
The structural characterization of biomaterials is challenging because they are usually too large for NMR or high resolution mass spectrometry and not well-enough structured for X-ray crystallography. Structural characterization and kinetic analysis for such systems thus has to proceed by collecting complementary data from a wide range of different techniques. This tutorial review describes how linear dichroism, a polarized absorbance spectroscopy technique applied to oriented molecular systems, can be used to provide useful data on biomaterials. In particular LD can provide information about relative orientations of sub-units of biomaterials and orientations of the whole biomaterial with respect to an orientation axis. An outline of linear dichroism and a summary of the artifacts to be avoided are followed by a description of how Couette flow linear dichroism has been used for a range of biomaterial systems including: DNA; DNA: ligand systems; cytoskeletal fibrous proteins; synthetic protein fibres; membrane proteins in liposomes; bacteriophage; carbon nanotubes; and peptidoglycan systems.
Item Type: | Journal Item | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry Q Science > QP Physiology |
||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Library of Congress Subject Headings (LCSH): | Linear dichroism, Nanotubes, Biomedical materials -- Imaging compatibility, Biomedical materials -- Research, Circular dichroism, DNA-ligand interactions | ||||
Journal or Publication Title: | Chemical Society Reviews | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 0306-0012 | ||||
Official Date: | September 2010 | ||||
Dates: |
|
||||
Volume: | Vol.39 | ||||
Number: | No.9 | ||||
Number of Pages: | 14 | ||||
Page Range: | pp. 3380-3393 | ||||
DOI: | 10.1039/b912917k | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |