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Response to comment on : Harte et al. High fat intake leads to acute postprandial exposure to circulating endotoxin in Type 2 diabetic subjects. Diabetes Care 2012;35:375-382
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Harte, A. L. (Alison L.) and McTernan, P. G. (Philip G.) (2013) Response to comment on : Harte et al. High fat intake leads to acute postprandial exposure to circulating endotoxin in Type 2 diabetic subjects. Diabetes Care 2012;35:375-382. Diabetes Care, Volume 36 (Number 3). e43-e43. doi:10.2337/dc12-2301 ISSN 0149-5992.
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Official URL: http://dx.doi.org/10.2337/dc12-2301
Abstract
The letter from Hansen et al. (1) raises an interesting question regarding the complexity of metabolic endotoxinemia and inflammation in vivo. Hansen et al. suggest endotoxin activity should induce an inflammatory response in our cohorts, as noted in a previous in vivo study, where healthy patients were inoculated with endotoxin (1,2). This has two elements to consider: firstly, the impact of endotoxin on inflammation in subjects, and secondly, the measurement of circulating endotoxin.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | Diabetes Care | ||||
| Publisher: | American Diabetes Association | ||||
| ISSN: | 0149-5992 | ||||
| Official Date: | 2013 | ||||
| Dates: |
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| Volume: | Volume 36 | ||||
| Number: | Number 3 | ||||
| Page Range: | e43-e43 | ||||
| DOI: | 10.2337/dc12-2301 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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