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Identification of group B respiratory syncytial viruses that lack the 60-nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya
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Agoti, Charles N., Gitahi, Caroline W., Medley, Graham, Cane, Patricia and Nokes, D. James (2013) Identification of group B respiratory syncytial viruses that lack the 60-nucleotide duplication after six consecutive epidemics of total BA dominance at coastal Kenya. Influenza and Other Respiratory Viruses, Volume 7 (Number 6). pp. 1008-1012. doi:10.1111/irv.12131 ISSN 1750-2640.
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WRAP_Nokes_irv12131.pdf - Published Version Available under License Creative Commons Attribution. Download (394Kb) | Preview |
Official URL: http://dx.doi.org/10.1111/irv.12131
Abstract
Respiratory syncytial virus BA genotype has reportedly replaced other group B genotypes worldwide. We report the observation of three group B viruses, all identical in G sequence but lacking the BA duplication, at a coastal district hospital in Kenya in early 2012. This follows a period of six consecutive respiratory syncytial virus (RSV) epidemics with 100% BA dominance among group B isolates. The new strains appear only distantly related to BA variants and to previously circulating SAB1 viruses last seen in the district in 2005, suggesting that they were circulating elsewhere undetected. These results are of relevance to an understanding of RSV persistence.
| Item Type: | Journal Article | ||||||||
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| Subjects: | Q Science > QH Natural history > QH426 Genetics Q Science > QR Microbiology > QR355 Virology R Medicine > R Medicine (General) |
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| Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||
| Library of Congress Subject Headings (LCSH): | Respiratory syncytial virus -- Kenya, Respiratory organs -- Diseases -- Kenya, Virus diseases -- Genetic aspects | ||||||||
| Journal or Publication Title: | Influenza and Other Respiratory Viruses | ||||||||
| Publisher: | Wiley-Blackwell Publishing Ltd. | ||||||||
| ISSN: | 1750-2640 | ||||||||
| Official Date: | 5 November 2013 | ||||||||
| Dates: |
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| Volume: | Volume 7 | ||||||||
| Number: | Number 6 | ||||||||
| Page Range: | pp. 1008-1012 | ||||||||
| DOI: | 10.1111/irv.12131 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 25 December 2015 | ||||||||
| Date of first compliant Open Access: | 25 December 2015 | ||||||||
| Funder: | Wellcome Trust (London, England) | ||||||||
| Grant number: | 084633, 084538 (WT) |
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