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Towards a behavioral phenotype for Rett syndrome
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Mount, Rebecca H, Hastings, Richard P., Reilly, Sheena, Cass, Hilary and Charman, Tony (2003) Towards a behavioral phenotype for Rett syndrome. American Journal of Mental Retardation : AJMR, Volume 108 (Number 1). pp. 1-12. doi:10.1352/0895-8017(2003)108<0001:TABPFR>2.0.CO;2 ISSN 0895-8017.
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Official URL: http://www.aaiddjournals.org/doi/abs/10.1352/0895-...
Abstract
Despite considerable interest in Rett syndrome, there have been few studies of associated behavioral and emotional problems. In the present study, 143 girls with Rett syndrome were compared on the Developmental Behavior Checklist with 85 girls with severe to profound mental retardation of mixed etiologies. After controlling for the effects of physical disabilities, we found that the girls with Rett syndrome presented more "autistic-relating" and fewer antisocial behaviors. A subsample of children with autism was also compared to the girls with Rett syndrome on autistic-relating behaviors, revealing that the Rett syndrome group did not present with classic autistic behavioral features The implications of these results for the identification of a Rett syndrome behavioral phenotype are discussed.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Social Sciences > Centre for Educational Development, Appraisal and Research (CEDAR) | ||||
Journal or Publication Title: | American Journal of Mental Retardation : AJMR | ||||
Publisher: | American Association on Intellectual and Developmental Disabilities | ||||
ISSN: | 0895-8017 | ||||
Official Date: | January 2003 | ||||
Dates: |
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Volume: | Volume 108 | ||||
Number: | Number 1 | ||||
Page Range: | pp. 1-12 | ||||
DOI: | 10.1352/0895-8017(2003)108<0001:TABPFR>2.0.CO;2 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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