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Classification of colon biopsy samples by spatial analysis of a single spectral band from its hyperspectral cube
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Masood, Khalid and Rajpoot, Nasir M. (Nasir Mahmood) (2007) Classification of colon biopsy samples by spatial analysis of a single spectral band from its hyperspectral cube. In: 11th Medical Image Understanding and Analysis (MIUA 2007), Aberystwyth, Wales, 17-18 Jul 2007 (Unpublished)
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Abstract
The histopathological analysis of colon biopsy samples is a very important part of screening for colorectal cancer. There is, however, significant inter-observer and even intra-observer variability in the results of such analysis due to its very subjective nature. Therefore, quantitative methods are required for the analysis of histopathological images to aid the histopatholgists in their diagnosis. In this paper, we exploit the shape and structure of the gland nuclei cells for the classification of colon biopsy samples using two-dimensional principal component analysis (2DPCA) and Support Vector Machine (SVM). We conclude that the use of textural features extracted from non-overlapping blocks of the histopathological images results in a non-linear decision boundary which can be efficiently exploited using a SVM with appropriate choice of parameters for its Gaussian kernel. The SVM classifier outperforms all the remaining methods by a clear margin.
Item Type: | Conference Item (Paper) | ||||
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Subjects: | R Medicine > R Medicine (General) T Technology > TA Engineering (General). Civil engineering (General) |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Computer Science | ||||
Library of Congress Subject Headings (LCSH): | Colon (Anatomy) -- Cancer -- Diagnosis, Image analysis | ||||
Official Date: | July 2007 | ||||
Dates: |
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Status: | Peer Reviewed | ||||
Publication Status: | Unpublished | ||||
Date of first compliant deposit: | 28 July 2016 | ||||
Date of first compliant Open Access: | 28 July 2016 | ||||
Conference Paper Type: | Paper | ||||
Title of Event: | 11th Medical Image Understanding and Analysis (MIUA 2007) | ||||
Type of Event: | Conference | ||||
Location of Event: | Aberystwyth, Wales | ||||
Date(s) of Event: | 17-18 Jul 2007 | ||||
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