The Library
Asymmetric reduction of diynones and the total synthesis of (S)-panaxjapyne A
Tools
Fang, Zhijia and Wills, Martin (2014) Asymmetric reduction of diynones and the total synthesis of (S)-panaxjapyne A. Organic Letters, Volume 16 (Number 2). pp. 374-377. doi:10.1021/ol4032123 ISSN 1523-7060.
|
PDF
WRAP-asymmetric-reduction-diynones-total-synthesis-(S)-panaxjapyne-A-Wills-2014.pdf - Accepted Version - Requires a PDF viewer. Download (778Kb) | Preview |
|
|
PDF
WRAP-supporting-information-Wills-2018.pdf - Supplemental Material - Requires a PDF viewer. Download (5Mb) | Preview |
Official URL: http://dx.doi.org/10.1021/ol4032123
Abstract
The asymmetric transfer hydrogenation of a series of diynones has been achieved in high conversion and enantiomeric induction. When R1 is a phenyl group, a competing alkyne reduction takes place; however, when R1 is an alkyl group, this side-reaction is not observed. The application of the reduction to the total synthesis of the natural product (S)-panaxjapyne A in high enantiomeric excess is described.
Item Type: | Journal Article | ||||||||
---|---|---|---|---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||||||
Journal or Publication Title: | Organic Letters | ||||||||
Publisher: | American Chemical Society | ||||||||
ISSN: | 1523-7060 | ||||||||
Official Date: | 2014 | ||||||||
Dates: |
|
||||||||
Volume: | Volume 16 | ||||||||
Number: | Number 2 | ||||||||
Page Range: | pp. 374-377 | ||||||||
DOI: | 10.1021/ol4032123 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||||
Date of first compliant deposit: | 20 November 2018 | ||||||||
Date of first compliant Open Access: | 20 November 2018 |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year