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Cross-sectional study of sleep quantity and quality and amnestic and non-amnestic cognitive function in an ageing population : the English longitudinal study of ageing (ELSA)
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Miller, Michelle A., Wright, Hayley, Ji, Chen and Cappuccio, Francesco (2014) Cross-sectional study of sleep quantity and quality and amnestic and non-amnestic cognitive function in an ageing population : the English longitudinal study of ageing (ELSA). PLoS One, Volume 9 (Numbe 6). Article number e100991. doi:10.1371/journal.pone.0100991 ISSN 1932-6203.
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Official URL: http://dx.doi.org/10.1371/journal.pone.0100991
Abstract
Background
The aim was to investigate the association between sleep disturbances and cognitive function in younger and older individuals from an ageing population.
Methods
3,968 male and 4,821 female white participants, aged 50 years and over, from the English Longitudinal Study of Ageing (ELSA) were studied. Information on sleep quality and quantity as well as both amnestic (memory, ACF) and non-amnestic (non-memory, nACF) function was available at Wave 4 (2008). Analysis of covariance was used to evaluate the relationship between sleep and cognitive function.
Results
After adjustment for multiple confounders in the younger group (50–64 years) duration of sleep explained 15.2% of the variance in ACF (p = 0.003) and 20.6% of nACF (p = 0.010). In the older group (65+ years) the estimates were 21.3% (p<0.001) and 25.6% (p<0.001), respectively. For sleep quality, there was a statistically significant association between sleep quality and both ACF (p<0.001) and nACF (p<0.001) in the older age group, but not in the younger age group (p = 0.586 and p = 0.373, respectively; interaction between age and sleep quality in the study sample including both age groups: p<0.001 for ACF and p = 0.018 for nACF). Sleep quality explained between 15.1% and 25.5% of the variance in cognition. The interaction with age was independent of duration of sleep. At any level of sleep duration there was a steeper association between sleep quality and ACF in the older than the younger group.
Conclusions
The associations between sleep disturbances and cognitive function vary between younger and older adults. Prospective studies will determine the temporal relationships between sleep disturbances and changes in cognition in different age groups.
Item Type: | Journal Article | ||||||||
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Subjects: | B Philosophy. Psychology. Religion > BF Psychology H Social Sciences > HQ The family. Marriage. Woman H Social Sciences > HV Social pathology. Social and public welfare Q Science > QP Physiology R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Sleep, Sleep -- Physiological aspects, Sleep disorders, Sleep disorders -- Age factors -- Complications, Sleep deprivation -- Age factors, Aging, Older people, Cognition in old age, Human information processing -- Age factors | ||||||||
Journal or Publication Title: | PLoS One | ||||||||
Publisher: | Public Library of Science | ||||||||
ISSN: | 1932-6203 | ||||||||
Official Date: | 26 June 2014 | ||||||||
Dates: |
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Volume: | Volume 9 | ||||||||
Number: | Numbe 6 | ||||||||
Article Number: | Article number e100991 | ||||||||
DOI: | 10.1371/journal.pone.0100991 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Date of first compliant deposit: | 27 December 2015 | ||||||||
Date of first compliant Open Access: | 27 December 2015 | ||||||||
Funder: | Economic and Social Research Council (Great Britain) (ESRC) | ||||||||
Grant number: | ES/K002910/1 (ESRC), |
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