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Cascade diagrams for depicting complex interventions in randomised trials
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Hooper, R., Froud, Robert J., Bremner, Stephen A., Perera, R. and Eldridge, Sandra (2013) Cascade diagrams for depicting complex interventions in randomised trials. BMJ, Volume 347 . Article number f6681. doi:10.1136/bmj.f6681 ISSN 0959-535X.
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Official URL: http://dx.doi.org/10.1136/bmj.f6681
Abstract
Many medical interventions—particularly non-pharmacological
ones—are complex, consisting of multiple interacting
components targeted at different organisational levels.1 2
Published descriptions of complex interventions often do not
contain enough detail to enable their replication.2-5 Reports of
behaviour change interventions should include descriptions of
setting, mode, intensity, and duration, and characteristics of the
participants.6 Graphical methods, such as that showing the
relative timing of assessments and intervention components,7
may improve clarity of reporting. However, these approaches
do not reveal the connections between the different “actors” in
a complex intervention.8 Different audiences may want different
things from a description of an intervention, but visualising
relationships between actors can clarify crucial features such
as the fidelity with which the intervention is passed down a
chain of actors
and possible routes of contamination between
treatment arms. Here we describe a new graphical approach—the
cascade diagram—that highlights these potential problems.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RA Public aspects of medicine R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Medical statistics , Clinical trials -- Charts, diagrams, etc., Biometry | ||||
| Journal or Publication Title: | BMJ | ||||
| Publisher: | BMJ Publishing Group Ltd. | ||||
| ISSN: | 0959-535X | ||||
| Official Date: | 15 November 2013 | ||||
| Dates: |
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| Volume: | Volume 347 | ||||
| Article Number: | Article number f6681 | ||||
| DOI: | 10.1136/bmj.f6681 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Date of first compliant deposit: | 28 December 2015 | ||||
| Date of first compliant Open Access: | 28 December 2015 |
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