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Comparison of several data-driven non-linear system identification methods on a simplified glucoregulatory system example

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Marconato, A., Schoukens, M., Tiels, K., Widanage, Widanalage Dhammika, Abu-Rmileh, A. and Schoukens, Johan (2014) Comparison of several data-driven non-linear system identification methods on a simplified glucoregulatory system example. IET Control Theory and Applications, 8 (17). pp. 1921-1930. doi:10.1049/iet-cta.2014.0534 ISSN 1751-8644.

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Official URL: http://dx.doi.org/10.1049/iet-cta.2014.0534

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Abstract

In this study, several advanced data-driven non-linear identification techniques are compared on a specific problem: a simplified glucoregulatory system modelling example. This problem represents a challenge in the development of an artificial pancreas for Type 1 diabetes mellitus treatment, since for this application good non-linear models are needed to design accurate closed-loop controllers to regulate the glucose level in the blood. Block-oriented as well as state-space models are used to describe both the dynamics and the non-linear behaviour of the insulin–glucose system, and the advantages and drawbacks of each method are pointed out. The obtained non-linear models are accurate in simulating the patient's behaviour, and some of them are also sufficiently simple to be considered in the implementation of a model-based controller to develop the artificial pancreas.

Item Type: Journal Article
Subjects: Q Science > QA Mathematics > QA75 (Please use QA76 Electronic Computers. Computer Science)
R Medicine > RC Internal medicine
Divisions: Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group)
Library of Congress Subject Headings (LCSH): System identification -- Research, Nonlinear theories, Drug delivery systems -- Mathematical models, Diabetes -- Treatment
Journal or Publication Title: IET Control Theory and Applications
Publisher: Institution of Engineering and Technology
ISSN: 1751-8644
Official Date: 2014
Dates:
DateEvent
2014Published
Volume: 8
Number: 17
Page Range: pp. 1921-1930
DOI: 10.1049/iet-cta.2014.0534
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
UNSPECIFIEDFonds voor wetenschappelijk onderzoek-Vlaanderenhttp://viaf.org/viaf/124392886
METH1Flemish Government UNSPECIFIED
IAP VI/4Federal Government of BelgiumUNSPECIFIED
UNSPECIFIEDEuropean Research Councilhttp://dx.doi.org/10.13039/501100000781
UNSPECIFIEDUniversity of GironaUNSPECIFIED

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