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KiT : a MATLAB package for kinetochore tracking
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Armond, Jonathan W., Vladimirou, Elina, McAinsh, Andrew D. and Burroughs, Nigel John (2016) KiT : a MATLAB package for kinetochore tracking. Bioinformatics, 32 (12). pp. 1917-1919. doi:10.1093/bioinformatics/btw087
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WRAP_Bioinformatics-2016-Armond-bioinformatics-btw087.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (295Kb) | Preview |
Official URL: http://dx.doi.org/10.1093/bioinformatics/btw087
Abstract
Summary: During mitosis, chromosomes are attached to the mitotic spindle via large protein complexes called kinetochores. The motion of kinetochores throughout mitosis is intricate and automated quantitative tracking of their motion has already revealed many surprising facets of their behaviour. Here, we present ‘KiT’ (Kinetochore Tracking)—an easy-to-use, open-source software package for tracking kinetochores from live-cell fluorescent movies. KiT supports 2D, 3D and multi-colour movies, quantification of fluorescence, integrated deconvolution, parallel execution and multiple algorithms for particle localization.
| Item Type: | Journal Article | ||||||||||
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| Subjects: | Q Science > QA Mathematics > QA76 Electronic computers. Computer science. Computer software Q Science > QR Microbiology |
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| Divisions: | Faculty of Medicine > Warwick Medical School > Biomedical Sciences > Cell & Developmental Biology Faculty of Science > Mathematics Faculty of Science > Centre for Systems Biology Faculty of Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Mitosis -- Software -- Research, Chromosomes, Proteins, Open source software | ||||||||||
| Journal or Publication Title: | Bioinformatics | ||||||||||
| Publisher: | Oxford University Press | ||||||||||
| ISSN: | 1367-4803 | ||||||||||
| Official Date: | 15 June 2016 | ||||||||||
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| Date of first compliant deposit: | 16 March 2016 | ||||||||||
| Volume: | 32 | ||||||||||
| Number: | 12 | ||||||||||
| Page Range: | pp. 1917-1919 | ||||||||||
| DOI: | 10.1093/bioinformatics/btw087 | ||||||||||
| Status: | Peer Reviewed | ||||||||||
| Publication Status: | Published | ||||||||||
| Access rights to Published version: | Open Access | ||||||||||
| Funder: | Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | ||||||||||
| Grant number: | BB/I021353/1 |
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