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KiT : a MATLAB package for kinetochore tracking

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Armond, Jonathan W., Vladimirou, Elina, McAinsh, Andrew D. and Burroughs, Nigel John (2016) KiT : a MATLAB package for kinetochore tracking. Bioinformatics, 32 (12). pp. 1917-1919. doi:10.1093/bioinformatics/btw087 ISSN 1367-4803.

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Official URL: http://dx.doi.org/10.1093/bioinformatics/btw087

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Abstract

Summary: During mitosis, chromosomes are attached to the mitotic spindle via large protein complexes called kinetochores. The motion of kinetochores throughout mitosis is intricate and automated quantitative tracking of their motion has already revealed many surprising facets of their behaviour. Here, we present ‘KiT’ (Kinetochore Tracking)—an easy-to-use, open-source software package for tracking kinetochores from live-cell fluorescent movies. KiT supports 2D, 3D and multi-colour movies, quantification of fluorescence, integrated deconvolution, parallel execution and multiple algorithms for particle localization.

Item Type: Journal Article
Subjects: Q Science > QA Mathematics > QA76 Electronic computers. Computer science. Computer software
Q Science > QR Microbiology
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Cell & Developmental Biology
Faculty of Science, Engineering and Medicine > Science > Mathematics
Faculty of Science, Engineering and Medicine > Research Centres > Warwick Systems Biology Centre
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Mitosis -- Software -- Research, Chromosomes, Proteins, Open source software
Journal or Publication Title: Bioinformatics
Publisher: Oxford University Press
ISSN: 1367-4803
Official Date: 15 June 2016
Dates:
DateEvent
15 June 2016Published
15 February 2016Available
6 February 2016Accepted
22 October 2015Submitted
Volume: 32
Number: 12
Page Range: pp. 1917-1919
DOI: 10.1093/bioinformatics/btw087
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 16 March 2016
Date of first compliant Open Access: 16 March 2016
Funder: Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Grant number: BB/I021353/1

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