The Library
Transperineal prostate biopsies for diagnosis of prostate cancer are well tolerated : a prospective study using patient reported outcome measures
Tools
Wadhwa, Karan, Carmona-Echeveria, Lina, Kuru, Timur, Gaziev, Gabriele, Serrao, Eva, Parashar, D., Frey, Julia, Dimov, Ivailo, Seidenader, Jonas, Acher, Pete, Muir, Gordon, Doble, Andrew, Gnanapragasam, Vincent J., Hadaschik, Boris and Kastner, Christof (2016) Transperineal prostate biopsies for diagnosis of prostate cancer are well tolerated : a prospective study using patient reported outcome measures. Asian Journal of Andrology, 19 (1). pp. 62-66. doi:10.4103/1008-682X.173453 ISSN 1008-682X.
|
PDF
WRAP_AsianJAndrol000-227073_061827.pdf - Requires a PDF viewer. Available under License Creative Commons Attribution Non-commercial Share Alike. Download (577Kb) | Preview |
Official URL: http://dx.doi.org/10.4103/1008-682X.173453
Abstract
We aimed to determine short‑term patient‑reported outcomes in men having general anesthetic transperineal (TP) prostate biopsies. A prospective cohort study was performed in men having a diagnostic TP biopsy. This was done using a validated and adapted questionnaire immediately post-biopsy and at follow‑up of between 7 and 14 days across three tertiary referral hospitals with a response rate of 51.6%. Immediately after biopsy 43/201 (21.4%) of men felt light‑headed, syncopal, or suffered syncope. Fifty‑three percent of men felt discomfort after biopsy (with 95% scoring <5 in a 0–10 scale). Twelve out of 196 men (6.1%) felt pain immediately after the procedure. Despite a high incidence of symptoms (e.g., up to 75% had some hematuria, 47% suffered some pain), it was not a moderate or serious problem for most, apart from hemoejaculate which 31 men suffered. Eleven men needed catheterization (5.5%). There were no inpatient admissions due to complications (hematuria, sepsis). On repeat questioning at a later time point, only 25/199 (12.6%) of men said repeat biopsy would be a significant problem despite a significant and marked reduction in erectile function after the procedure. From this study, we conclude that TP biopsy is well tolerated with similar side effect profiles and attitudes of men to repeat biopsy to men having TRUS biopsies. These data allow informed counseling of men prior to TP biopsy and a benchmark for tolerability with local anesthetic TP biopsies being developed for clinical use.
Item Type: | Journal Article | ||||||||
---|---|---|---|---|---|---|---|---|---|
Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Cancer Research Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Statistics and Epidemiology Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||||||
Library of Congress Subject Headings (LCSH): | Prostate -- Biopsy, Prostate -- Cancer, Patient satisfaction | ||||||||
Journal or Publication Title: | Asian Journal of Andrology | ||||||||
Publisher: | Medknow Publications and Media Pvt. Ltd. | ||||||||
ISSN: | 1008-682X | ||||||||
Official Date: | 26 February 2016 | ||||||||
Dates: |
|
||||||||
Volume: | 19 | ||||||||
Number: | 1 | ||||||||
Page Range: | pp. 62-66 | ||||||||
DOI: | 10.4103/1008-682X.173453 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Funder: | Medical Research Council (Great Britain) (MRC) |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year