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Comparative modelling of protein structure and its impact on microbial cell factories
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Centeno, N. B., Planas-Iglesias, Joan and Oliva, B. (2005) Comparative modelling of protein structure and its impact on microbial cell factories. Microbial Cell Factories, 4 . 20. doi:10.1186/1475-2859-4-20 ISSN 1475-2859.
An open access version can be found in:
Official URL: http://microbialcellfactories.biomedcentral.com/ar...
Abstract
Comparative modeling is becoming an increasingly helpful technique in microbial cell factories as the knowledge of the three-dimensional structure of a protein would be an invaluable aid to solve problems on protein production. For this reason, an introduction to comparative modeling is presented, with special emphasis on the basic concepts, opportunities and challenges of protein structure prediction. This review is intended to serve as a guide for the biologist who has no special expertise and who is not involved in the determination of protein structure. Selected applications of comparative modeling in microbial cell factories are outlined, and the role of microbial cell factories in the structural genomics initiative is discussed.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Microbial Cell Factories | ||||
Publisher: | BioMed Central Ltd. | ||||
ISSN: | 1475-2859 | ||||
Official Date: | 2005 | ||||
Dates: |
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Volume: | 4 | ||||
Article Number: | 20 | ||||
DOI: | 10.1186/1475-2859-4-20 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Open Access (Creative Commons) | ||||
Open Access Version: |
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