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Functional and morphological development of the womb throughout life
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Sheldon, Rachel E., Shmygol, Anatoly, Berg, Hugo van den and Blanks, Andrew M. (2015) Functional and morphological development of the womb throughout life. Science progress, 98 (Pt 2). pp. 103-127. doi:10.3184/003685015X14308363103415 ISSN 0036-8504.
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Official URL: http://dx.doi.org/10.3184/003685015X14308363103415
Abstract
The uterus undergoes changes throughout a woman's life, beginning with her own embryonic development when she is still in the womb, commencing a monthly cycle at the onset of adulthood, and undergoing dramatic changes during pregnancy and parturition. The impact of preterm labour and other perinatal health problems is significant, both in human and financial terms; therefore the study of the physiological and regulatory changes which the uterus undergoes can be of enormous potential benefit. Here we briefly review the current state of knowledge, with an emphasis on the importance of changes in connectivity in the uterine smooth muscle cell network and on recent mathematical modelling work aimed at elucidating the role of spatial heterogeneity in this connected network.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Mathematics Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Reproductive Health ( - until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Science progress | ||||
ISSN: | 0036-8504 | ||||
Official Date: | 1 June 2015 | ||||
Dates: |
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Volume: | 98 | ||||
Number: | Pt 2 | ||||
Page Range: | pp. 103-127 | ||||
DOI: | 10.3184/003685015X14308363103415 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
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