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Delineating noncovalent interactions between the azinomycins and double-stranded DNA: Importance of the naphthalene substitution pattern on interstrand cross-linking efficiency
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UNSPECIFIED (2004) Delineating noncovalent interactions between the azinomycins and double-stranded DNA: Importance of the naphthalene substitution pattern on interstrand cross-linking efficiency. ORGANIC LETTERS, 6 (20). pp. 3505-3507. doi:10.1021/ol048653y ISSN 1523-7060.
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Official URL: http://dx.doi.org/10.1021/ol048653y
Abstract
Using a series of synthetic azinomycin analogues, it is shown that the efficiency of in vitro DNA interstrand cross-linking is markedly reduced when either the C-5' methyl group or both the C-5' methyl and C-3' methoxy groups are deleted from the naphthalene ring.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Journal or Publication Title: | ORGANIC LETTERS | ||||
Publisher: | AMER CHEMICAL SOC | ||||
ISSN: | 1523-7060 | ||||
Official Date: | 30 September 2004 | ||||
Dates: |
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Volume: | 6 | ||||
Number: | 20 | ||||
Number of Pages: | 3 | ||||
Page Range: | pp. 3505-3507 | ||||
DOI: | 10.1021/ol048653y | ||||
Publication Status: | Published |
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