Alam, Mohammad Tauqee, Takano, Eriko and Breitling, Rainer (2011) Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor. BMC Research Notes, 4 . p. 325. doi:10.1186/1756-0500-4-325 ISSN 1756-0500.

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Abstract

Streptomyces coelicolor, a model organism of antibiotic producing bacteria, has one of the largest genomes of the bacterial kingdom, including 7825 predicted protein coding genes. A large number of these genes, nearly 34%, are functionally orphan (hypothetical proteins with unknown function). However, in gene expression time course data, many of these functionally orphan genes show interesting expression patterns.

Item Type:	Journal Article
Subjects:	Q Science > QH Natural history Q Science > QR Microbiology
Divisions:	Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Streptomyces coelicolor -- Genetic aspects
Journal or Publication Title:	BMC Research Notes
Publisher:	BioMed Central Ltd.
ISSN:	1756-0500
Official Date:	7 September 2011
Dates:	Date Event 7 September 2011 Published 7 September 2011 Accepted 30 May 2011 Submitted
Volume:	4
Page Range:	p. 325
DOI:	10.1186/1756-0500-4-325
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access (Creative Commons)
Funder:	Groningen Biomolecular Sciences and Biotechnology Institute (GBB), Rijksuniversiteit te Groningen [University of Groningen], Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Netherlands Organisation for Scientific Research] (NWO)

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