The Library
Host-seeking activity of a Tanzanian population of Anopheles arabiensis at an insecticide treated bed net
Tools
Tools
Tools
Parker, Josephine E. A., Angarita Jaimes, Natalia C., Gleave, Katherine, Mashauri, Fabian, Abe, Mayumi, Martine, Jackline, Towers, Catherine E., Towers, David P. and McCall, Philip J. (2017) Host-seeking activity of a Tanzanian population of Anopheles arabiensis at an insecticide treated bed net. Malaria Journal, 16 (1). 270. doi:10.1186/s12936-017-1909-6 ISSN 1475-2875.
|
PDF
WRAP-host-seeking-activity-Tanzanian-population-Towers-2017.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (2656Kb) | Preview |
Official URL: https://doi.org/10.1186/s12936-017-1909-6
Abstract
Background:
Understanding how mosquitoes respond to long lasting insecticide treated nets (LLINs) is fundamental to sustaining the effectiveness of this essential control tool. We report on studies with a tracking system to investigate behaviour of wild anophelines at an LLIN, in an experimental hut at a rural site in Mwanza, Tanzania.
Methods:
Groups of adult female mosquitoes (n = 10 per replicate) reared from larvae of a local population, identified as predominantly (95%) Anopheles arabiensis, were released in the hut. An infrared video tracking system recorded flight and net contact activity over 1 h as the mosquitoes attempted to reach a supine human volunteer within a bed net (either a deltamethrin-treated LLIN or an untreated control net). A range of activities, including flight path, position in relation to the bed net and duration of net contact, were quantified and compared between treatments.
Results:
The total time that female An. arabiensis spent in flight around LLINs was significantly lower than at untreated nets [F(1,10) = 9.26, p = 0.012], primarily due to a substantial reduction in the time mosquitoes spent in persistent ‘bouncing’ flight [F(1,10) = 18.48, p = 0.002]. Most activity occurred at the net roof but significantly less so with LLINs (56.8% of total) than untreated nets [85.0%; Χ2 (15) = 234.69, p < 0.001]. Activity levels at the bed net directly above the host torso were significantly higher with untreated nets (74.2%) than LLINs [38.4%; Χ2 (15) = 33.54, p = 0.004]. ‘Visiting’ and ‘bouncing’ rates were highest above the volunteer’s chest in untreated nets (39.9 and 50.4%, respectively) and LLINs [29.9 and 42.4%; Χ2 (13) = 89.91, p < 0.001; Χ2 (9) = 45.73, p < 0.001]. Highest resting rates were above the torso in untreated nets [77%; Χ2 (9) = 63.12, p < 0.001], but in LLINs only 33.2% of resting occurred here [Χ2 (9) = 27.59, p = 0.001], with resting times spread between the short vertical side of the net adjacent to the volunteer’s head (21.8%) and feet (16.2%). Duration of net contact by a single mosquito was estimated at 204–290 s on untreated nets and 46–82 s on LLINs. While latency to net contact was similar in both treatments, the reduction in activity over 60 min was significantly more rapid for LLINs [F(1,10) = 6.81, p = 0.026], reiterating an ‘attract and kill’ rather than a repellent mode of action.
Conclusions:
The study has demonstrated the potential for detailed investigations of behaviour of wild mosquito populations under field conditions. The results validate the findings of earlier laboratory studies on mosquito activity at LLINs, and reinforce the key role of multiple brief contacts at the net roof as the critical LLIN mode of action.
| Item Type: | Journal Article | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine | |||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | |||||||||
| SWORD Depositor: | Library Publications Router | |||||||||
| Library of Congress Subject Headings (LCSH): | Malaria -- Control --Tanzania., Mosquitoes -- Control., Insecticide-treated mosquito nets. | |||||||||
| Journal or Publication Title: | Malaria Journal | |||||||||
| Publisher: | BioMed Central Ltd. | |||||||||
| ISSN: | 1475-2875 | |||||||||
| Official Date: | 4 July 2017 | |||||||||
| Dates: |
|
|||||||||
| Volume: | 16 | |||||||||
| Number: | 1 | |||||||||
| Article Number: | 270 | |||||||||
| DOI: | 10.1186/s12936-017-1909-6 | |||||||||
| Status: | Peer Reviewed | |||||||||
| Publication Status: | Published | |||||||||
| Reuse Statement (publisher, data, author rights): | ** From PubMed via Jisc Publications Router. ** History: ** received: 23-02-2017 ** accepted: 26-06-2017 | |||||||||
| Access rights to Published version: | Open Access (Creative Commons) | |||||||||
| Date of first compliant deposit: | 19 September 2017 | |||||||||
| Date of first compliant Open Access: | 20 September 2017 | |||||||||
| Funder: | Seventh Framework Programme (European Commission) (FP7), Medical Research Council (Canada) (MRC) | |||||||||
| Grant number: | 265660 ‘AvecNET’ , MR/M011941/1. | |||||||||
| RIOXX Funder/Project Grant: |
|
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
