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A one-pot process for the enantioselective synthesis of amines via reductive amination under transfer hydrogenation conditions
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UNSPECIFIED (2003) A one-pot process for the enantioselective synthesis of amines via reductive amination under transfer hydrogenation conditions. ORGANIC LETTERS, 5 (22). pp. 4227-4230. doi:10.1021/ol035746r ISSN 1523-7060.
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Official URL: http://dx.doi.org/10.1021/ol035746r
Abstract
Cyclic amines may be prepared via a sequence of deprotection followed by intramolecular reductive amination of t-Boc-protected amino ketones under asymmetric transfer hydrogenation conditions. In cases where the corresponding imine reaction proceeds with high enantioselectivity, this is reflected in the one-step process.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Journal or Publication Title: | ORGANIC LETTERS | ||||
Publisher: | AMER CHEMICAL SOC | ||||
ISSN: | 1523-7060 | ||||
Official Date: | 30 October 2003 | ||||
Dates: |
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Volume: | 5 | ||||
Number: | 22 | ||||
Number of Pages: | 4 | ||||
Page Range: | pp. 4227-4230 | ||||
DOI: | 10.1021/ol035746r | ||||
Publication Status: | Published |
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