
The Library
NMR-based assignment of isoleucine vs allo-isoleucine stereochemistry
Tools
Anderson, Zoe J., Hobson, Christian, Needley, Rebecca, Song, Lijiang, Perryman, Michael S., Kerby, Paul D. and Fox, David J. (2017) NMR-based assignment of isoleucine vs allo-isoleucine stereochemistry. Organic & Biomolecular Chemistry, 15 (44). 9372-9378 . doi:10.1039/C7OB01995E ISSN 1477-0520.
|
PDF
WRAP-NMR-based-assignment-isoleucine-alloisoleucine-Song-2017.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution. Download (671Kb) | Preview |
|
![]() |
PDF
WRAP-NMR-based-assignment-isoleucine-allo-isoleucine-stereochemistry-Fox-2017.pdf - Accepted Version Embargoed item. Restricted access to Repository staff only - Requires a PDF viewer. Download (751Kb) |
|
![]() |
Microsoft Word
Isoleucine SI - Copy.docx - Supplemental Material Embargoed item. Restricted access to Repository staff only Download (33Mb) |
Official URL: http://doi.org/10.1039/C7OB01995E
Abstract
A simple 1H and 13C NMR spectrometric analysis is demonstrated that permits differentiation of isoleucine and allo-isoleucine residues by inspection of the chemical shift and coupling constants of the signals associated with the proton and carbon at the α-stereocentre. This is applied to the estimation of epimerisation during metal-free N-arylation and peptide coupling reactions.
Item Type: | Journal Article | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry | |||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | |||||||||
Library of Congress Subject Headings (LCSH): | Stereochemistry, Nuclear magnetic resonance spectroscopy, Peptides, Amino acids | |||||||||
Journal or Publication Title: | Organic & Biomolecular Chemistry | |||||||||
Publisher: | Royal Society of Chemistry | |||||||||
ISSN: | 1477-0520 | |||||||||
Official Date: | 1 November 2017 | |||||||||
Dates: |
|
|||||||||
Volume: | 15 | |||||||||
Number: | 44 | |||||||||
Page Range: | 9372-9378 | |||||||||
DOI: | 10.1039/C7OB01995E | |||||||||
Status: | Peer Reviewed | |||||||||
Publication Status: | Published | |||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||
Date of first compliant deposit: | 25 September 2017 | |||||||||
Date of first compliant Open Access: | 28 March 2018 | |||||||||
RIOXX Funder/Project Grant: |
|
|||||||||
Related URLs: |
Request changes or add full text files to a record
Repository staff actions (login required)
![]() |
View Item |
Downloads
Downloads per month over past year