The Library
Borrowing of strength and study weights in multivariate and network meta-analysis
Tools
Jackson, Dan, White, Ian R., Price, Malcolm, Copas, John B. and Riley, Richard D. (2015) Borrowing of strength and study weights in multivariate and network meta-analysis. Statistical Methods in Medical Research, 26 (6). pp. 2853-2868. doi:10.1177/0962280215611702 ISSN 1477-0334.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: https://doi.org/10.1177/0962280215611702
Abstract
Multivariate and network meta-analysis have the potential for the estimated mean of one effect to borrow strength from the data on other effects of interest. The extent of this borrowing of strength is usually assessed informally. We present new mathematical definitions of ‘borrowing of strength’. Our main proposal is based on a decomposition of the score statistic, which we show can be interpreted as comparing the precision of estimates from the multivariate and univariate models. Our definition of borrowing of strength therefore emulates the usual informal assessment. We also derive a method for calculating study weights, which we embed into the same framework as our borrowing of strength statistics, so that percentage study weights can accompany the results from multivariate and network meta-analyses as they do in conventional univariate meta-analyses. Our proposals are illustrated using three meta-analyses involving correlated effects for multiple outcomes, multiple risk factor associations and multiple treatments (network meta-analysis).
Item Type: | Journal Article | ||||||
---|---|---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Science > Statistics | ||||||
SWORD Depositor: | Library Publications Router | ||||||
Journal or Publication Title: | Statistical Methods in Medical Research | ||||||
Publisher: | SAGE Publications | ||||||
ISSN: | 1477-0334 | ||||||
Official Date: | 1 December 2015 | ||||||
Dates: |
|
||||||
Volume: | 26 | ||||||
Number: | 6 | ||||||
Page Range: | pp. 2853-2868 | ||||||
DOI: | 10.1177/0962280215611702 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Reuse Statement (publisher, data, author rights): | ** From Crossref via Jisc Publications Router. | ||||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |