2023

(2023) The importance of clinicians' and parents' awareness of suicidal behaviour in adolescents reaching the upper age limit of their mental health services in Europe. Journal of Affective Disorders, 325 . pp. 360-368. doi:10.1016/j.jad.2022.12.164 ISSN 0165-0327. [ 🗎 Public]. [ (✓) hoa:511 ]

2022

(2022) Economic evaluation of shortened, bedaquiline-containing treatment regimens for rifampicin-resistant tuberculosis (STREAM stage 2) : a within-trial analysis of a randomised controlled trial. The Lancet Global Health . doi:10.1016/S2214-109X(22)00498-3 ISSN 2214-109X. [ 🗎 Public]. [ (✓) hoa:511 ] (In Press)

Arije, Olujide, Hlungwani, Tintswalo and Madan, Jason (2022) Key informants’ perspectives on policy- and service-level challenges and opportunities for delivering adolescent and youth-friendly health services in public health facilities in a Nigerian setting. BMC Health Services Research, 22 (1). 1493. doi:10.1186/s12913-022-08860-z ISSN 1472-6963. [ 🗎 Public]. [ (✓) hoa:511 ]

Arije, Olujide, Madan, Jason and Hlungwani, Tintswalo (2022) Quality of sexual and reproductive health services for adolescents and young people in public health facilities in Southwest Nigeria : a mystery client study. Global Health Action, 15 (1). 2145690. doi:10.1080/16549716.2022.2145690 ISSN 1654-9880. [ 🗎 Public]. [ (✓) hoa:511 ]

MILESTONE consortium (Including:

). (2022) Leaving child and adolescent mental health services in the MILESTONE cohort : a longitudinal cohort study on young people's mental health indicators, care pathways, and outcomes in Europe. The Lancet Psychiatry, 9 (12). pp. 944-956. doi:10.1016/S2215-0366(22)00310-8 ISSN 2215-0366. [ (🔓): Yes ].

(2022) Transforming access to care for serious mental disorders in slums (the TRANSFORM Project) : rationale, design and protocol. BJPsych Open, 8 (6). e185. doi:10.1192/bjo.2022.584 ISSN 2056-4724. [ 🗎 Public]. [ (🔓): Yes ].

Yiu, Hei Hang Edmund, Al-Janabi, Hareth, Stewart-Brown, Sarah L., Petrou, Stavros and Madan, Jason (2022) The use of composite time trade-off and discrete choice experiment methods for the valuation of the Short Warwick-Edinburgh Mental Well-being Scale (SWEMWBS) : a think-aloud study. Quality of Life Research, 31 . pp. 2739-2751. doi:10.1007/s11136-022-03123-0 ISSN 0962-9343. [ 🗎 Public]. [ (✓) hoa:511 ]

Connor, Charlotte, MBH, Yap, Warwick, Jane, Birchwood, M. J., De Valliere, Nicole, Madan, Jason, Melvin, Glenn A., Padfield, Emma, Patterson, Paul, Petrou, Stavros, Raynes, K., Stewart-Brown, Sarah L. and Thompson, Andrew D. (2022) An online parenting intervention to prevent affective disorders in high-risk adolescents : the PIPA trial protocol. Trials, 23 (1). 655. doi:10.1186/s13063-022-06563-8 ISSN 1745-6215. [ 🗎 Public]. [ (✓) hoa:511 ]

Tomeny, Ewan M., Nightingale, Rebecca, Chinoko, Beatrice, Nikolaidis, Georgios F., Madan, Jason J., Worrall, Eve, Ngwira, Lucky Gift, Banda, Ndaziona Peter, Lönnroth, Knut, Evans, Denise, Chakaya, Jeremiah, Rylance, Jamie, Mortimer, Kevin, Squire, S. Bertel and Meghji, Jamilah (2022) TB morbidity estimates overlook the contribution of post-TB disability : evidence from urban Malawi. BMJ Global Health, 7 (5). e007643. doi:10.1136/bmjgh-2021-007643 ISSN 2059-7908. [ 🗎 Public]. [ (✓) hoa:511 ]

Improving Health in Slums Collaborative (Including: Aujla, Navneet, Chen, Yen-Fu, Conlan, Christopher, Gill, Paramjit, Griffiths, Frances, Harris, Bronwyn, Madan, Jason, Muir, Helen, Oyebode, Oyinlola, Pitidis, Vangelis, de Albuquerque, João Porto , Smith, Simon, Taylor, Celia A., Tregonning, Grant, Ulbrich, Philipp, Uthman, Olalekan A., Wilson, Ria, Yeboah, Godwin and Park, Ji-Eun). (2022) Primary-care doctor and nurse consultations among people who live in slums : a retrospective, cross-sectional survey in four countries. BMJ Open, 12 (1). e054142. doi:10.1136/bmjopen-2021-054142 ISSN 2044-6055. [ 🗎 Public]. [ (🔓): Yes ].

2021

(2021) Cohort profile : demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe. BMJ Open, 11 (12). e053373. doi:10.1136/bmjopen-2021-053373 ISSN 2044-6055. [ 🗎 Public]. [ (✓) hoa:511 ]

Improving Health in Slums Collaborative (Including: Aujla, Navneet, Chen, Yen-Fu, Gill, Paramjit, Griffiths, Frances, Harris, Bronwyn, Madan, Jason, Muir, Helen, Oyebode, Oyinlola, Pitidis, Vangelis, de Albuquerque, João Porto , Smith, Simon, Taylor, Celia A., Ulbrich, Philipp, Uthman, Olalekan A., Wilson, Ria and Yeboah, Godwin). (2021) Inequity of healthcare access and use and catastrophic health spending in slum communities : a retrospective, cross-sectional survey in four countries. BMJ Global Health, 6 (11). e007265. doi:10.1136/bmjgh-2021-007265 ISSN 2059-7908. [ 🗎 Public]. [ (🔓): Yes ].

(2021) Effect of managed transition on mental health outcomes for young people at the child–adult mental health service boundary : a randomised clinical trial. Psychological Medicine . pp. 1-12. doi:10.1017/S0033291721003901 ISSN 0033-2917. [ 🗎 Public]. [ (✓) hoa:511 ] (In Press)

Collard, Victoria Elizabeth Janet, Moore, Corran, Nichols, Vivien P., Ellard, David R., Patel, Shilpa, Sandhu, Harbinder, Parsons, Helen, Sharma, U., Underwood, Martin, Madan, Jason and Tang, Nicole K. Y. (2021) Challenges and visions for managing pain-related insomnia in primary care using the hybrid CBT approach : a small-scale qualitative interview study with GPs, nurses, and practice managers. BMC Family Practice, 22 . 210. doi:10.1186/s12875-021-01552-3 ISSN 1471-2296. [ 🗎 Public]. [ (🔓): Yes ].

Schade, Alexander Thomas, Nyamulani, Nohakhelha, Banza, Leonard Ngoe, Metcalfe, Andrew John, Leather, Andrew, Madan, Jason J., Lallloo, David G., Harrison, Williams James and MacPherson, Peter (2021) Protocol for a prospective cohort study of open tibia fractures in Malawi with a nested implementation of open fracture guidelines. Wellcome Open Research, 6 . 228. doi:10.12688/wellcomeopenres.17145.1 ISSN 2398-502X. [ 🗎 Public]. [ (🔓): Yes ].

Improving Health in Slums Collaborative (Including:

). (2021) Pharmacies in informal settlements : a retrospective, cross-sectional household and health facility survey in four countries. BMC Health Services Research, 21 (1). 945 . doi:10.1186/s12913-021-06937-9 ISSN 1472-6963. [ 🗎 Public]. [ (✓) hoa:511 ]

Singh, Swaran P., Mohan, Mohapradeep, Iyer, Srividya N., Meyer, Caroline, Currie, Graeme, Shah, Jai, Madan, Jason, Birchwood, M. J., Sood, Mamta, Ramachandran, Padmavati, Chadda, Rakesh K., Lilford, Richard J., Rangaswamy, Thara and Furtado, Vivek (2021) The Warwick-India-Canada (WIC) global mental health group : rationale, design and protocol. BMJ Open, 11 . e046362. doi:10.1136/bmjopen-2020-046362 ISSN 2044-6055. [ 🗎 Public]. [ (🔓): Yes ].

Dhandapani, Vijaya Raghavan, Chandrasekaran, Sangeetha, Singh, Saurabh, Sood, Mamta, Chadda, Rakesh K, Shah, Jai, Iyer, Srividya, Meyer, Caroline, Mohan, Mohapradeep, Birchwood, Max, Madan, Jason, Currie, Graeme, Ramachandran, Padmavati, Rangaswamy, Thara and Singh, Swaran P. (2021) Community stakeholders' perspectives on youth mental health in India : problems, challenges and recommendations. Early Intervention in Psychiatry, 15 (3). pp. 716-722. doi:10.1111/eip.12984 ISSN 1751-7885. [ 🗎 Public]. [ (✓) hoa:511 ]

(2021) Analysis of OpenStreetMap data quality at different stages of a participatory mapping process : evidence from slums in Africa and Asia. ISPRS International Journal of Geo-Information, 10 (4). 265. doi:10.3390/ijgi10040265 ISSN 2220-9964. [ 🗎 Public]. [ (✓) hoa:511 ]

2020

Meghji, Jamilah, Gregorius, Stefanie, Madan, Jason, Chitimbe, Fatima, Thomson, Rachael, Rylance, Jamie, Banda, Ndaziona P. K., Gordon, Stephen B., Corbett, Elizabeth L., Mortimer, Kevin and Squire, Stephen Bertel (2020) The long term effect of pulmonary tuberculosis on income and employment in a low income, urban setting. Thorax, 76 (4). pp. 387-395. doi:10.1136/thoraxjnl-2020-215338 ISSN 0040-6376. [ 🗎 Public]. [ (🔓): Yes ].

Achana, Felix A., Petrou, Stavros, Madan, Jason, Khan, Kamran, Ji, Chen, Hossain, Anower, Lall, Ranjit, Slowther, Anne-Marie, Deakin, Charles D., Quinn, Tom, Nolan, Jerry P., Pocock, Helen, Rees, Nigel, Smyth, Michael A., Gates, Simon, Gardiner, Dale and Perkins, Gavin D. (2020) Cost-effectiveness of adrenaline for out-of-hospital cardiac arrest. Critical Care, 24 (1). 579. doi:10.1186/s13054-020-03271-0 ISSN 1466-609X. [ 🗎 Public]. [ (✓) hoa:511 ]

Madan, Jason, Bruce Kumar, Meghan, Taegtmeyer, Miriam, Barasa, Edwine and Singh, Swaran P. (2020) SEEP-CI : a structured economic evaluation process for complex Health system interventions. International Journal of Environmental Research and Public Health, 17 (18). 6780. doi:10.3390/ijerph17186780 ISSN 1660-4601. [ 🗎 Public]. [ (🔓): Yes ].

(2020) Transitioning from child to adult mental health services : what role for social services? Insights from a European survey. Journal of Children's Services, 15 (3). pp. 89-108. doi:10.1108/JCS-05-2020-0014 ISSN 1746-6660. [ 🗎 Public]. [ (✓) hoa:511 ]

(2020) Impact of the societal response to COVID-19 on access to healthcare for non-COVID-19 health issues in slum communities of Bangladesh, Kenya, Nigeria and Pakistan : results of pre-COVID and COVID-19 lockdown stakeholder engagements. BMJ Global Health, 5 (8). e003042. doi:10.1136/bmjgh-2020-003042 ISSN 2059-7908. [ 🗎 Public]. [ (✓) hoa:511 ]

(2020) Validation of the Transition Readiness and Appropriateness Measure (TRAM) for the Managing the Link and Strengthening Transition from Child to Adult Mental Healthcare in Europe (MILESTONE) study. BMJ Open, 10 (6). e033324. doi:10.1136/bmjopen-2019-033324 ISSN 2044-6055. [ 🗎 Public]. [ (✓) hoa:511 ]

Duncan, Craig, Weich, Scott, Moon, Graham, Twigg, Liz, Fenton, Sarah‐Jane, Bhui, Kamaldeep, Canaway, Alastair, Crepaz‐Keay, David, Keown, Patrick, Madan, Jason, McBride, Orla, Parsons, Helen and Singh, Swaran P. (2020) Moving beyond randomized controlled trials in the evaluation of compulsory community treatment. Journal of Evaluation in Clinical Practice, 26 (3). pp. 812-818. doi:10.1111/jep.13245 ISSN 1365-2753. [ 🗎 Public]. [ (✓) hoa:511 ]

Raja, Tasneem, Tuomainen, Helena, Madan, Jason, Mistry, Dipesh, Jain, Sanjeev and Singh, Swaran P. (2020) Psychiatric hospital reform in low-income and middle-income countries Structured Individualised inTervention And Recovery (SITAR) : a two-arm pragmatic randomised controlled trial study protocol. BMJ Open, 10 (5). e035753. doi:10.1136/bmjopen-2019-035753 ISSN 2044-6055. [ 🗎 Public]. [ (🔓): Yes ].

Weich, Scott, Fenton, Sarah-Jane Hannah, Staniszewska, Sophie, Canaway, Alastair, Crepaz-Keay, David, Larkin, Michael, Madan, Jason, Mockford, Carole, Bhui, Kamaldeep, Newton, Elizabeth, Croft, Charlotte, Foye, Una, Cairns, Aimee, Ormerod, Emma, Jeffreys, Stephen and Griffiths, Frances (2020) Using patient experience data to support improvements in inpatient mental health care : the EURIPIDES multimethod study. Health Services and Delivery Research, 8 (21). pp. 1-338. doi:10.3310/hsdr08210 ISSN 2050-4349. [ 🗎 Public]. [ (✓) hoa:511 ]

(2020) Protocol for the development and validation procedure of the managing the link and strengthening transition from child to adult mental health care (MILESTONE) suite of measures. BMC Pediatrics, 20 (1). doi:10.1186/s12887-020-02079-9 ISSN 1471-2431. [ 🗎 Public]. [ (✓) hoa:511 ]

Tang, Nicole K. Y., Moore, Corran, Parsons, Helen, Sandhu, Harbinder, Patel, Shilpa, Ellard, David R., Nichols, Vivien P., Madan, Jason, Collard, Victoria Elizabeth Janet, Sharma, Uma and Underwood, Martin (2020) Implementing a hybrid cognitive-behavioural therapy for pain-related insomnia in primary care : lessons learnt from a mixed-methods feasibility study. BMJ Open, 10 (3). e034764. doi:10.1136/bmjopen-2019-034764 ISSN 2044-6055. [ 🗎 Public]. [ (✓) hoa:511 ]

Weich, Scott, Duncan, Craig, Twigg, Liz, McBride, Orla, Parsons, Helen, Moon, Graham, Canaway, Alastair, Madan, Jason, Crepaz-Keay, David, Keown, Patrick, Singh, Swaran P. and Bhui, Kamaldeep (2020) Use of community treatment orders and their outcomes : an observational study. NIHR.

STREAM study health economic evaluation collaborators (Including: Madan, Jason, Rosu, Laura, Girma Tefera, Mamo, van Rensburg, Craig , Evans, Denise, Langley, Ivor, Tomeny, Ewan M., Nunn, Andrew, Phillips, Patrick P. J., Ruseng, I. D. and Squire, S. Bertel). (2020) Economic evaluation of short treatment for multidrugresistant tuberculosis, Ethiopia and South Africa : the STREAM trial. Bulletin of the World Health Organization . BLT.19.243584. ISSN 0042-9686. [ 🗎 Public]. [ (🔓): Yes ].

Costa, Matthew L., Achten, Juul, Knight, Ruth, Bruce, Julie, Dutton, Susan J., Madan, Jason, Dritsaki, Melina, Parsons, Nicholas R., Fernandez, Miguel, Grant, Richard and Nanchahal, Jagdeep (2020) Effect of incisional negative pressure wound therapy vs standard wound dressing on deep surgical site infection after surgery for lower limb fractures associated with major trauma : The WHIST randomized clinical trial. JAMA: The Journal of the American Medical Association, 323 (6). pp. 519-526. doi:10.1001/jama.2020.0059 ISSN 0098-7484.

2019

Cohen, Danielle B., Mbendera, Kuzani, Maheswaran, Hendramoorthy, Mukaka, Mavuto, Mangochi, Helen, Phiri, Linna, Madan, Jason, Davies, Geraint, Corbett, Elizabeth L. and Squire, Bertel (2019) Delivery of long-term-injectable agents for TB by lay carers : pragmatic randomised trial. Thorax, 75 (1). pp. 64-71. doi:10.1136/thoraxjnl-2018-212675 ISSN 0040-6376. [ 🗎 Public].

Warwick, Jane, Bouliotis, Georgios, Wells, Philip, Yujin, Lee, Madan, Jason, Cannaway, Alastair, Tuomainen, Helena and Singh, Swaran P. (2019) Methodological issues in trials of youth mental health : what have we learnt during the MILESTONE study. In: International Clinical Trials Methodology Conference (ICTMC 2019), Brighton, UK, 6-9 Oct 2019. Published in: Trials, 20 (Supplement 3). doi:10.1186/s13063-019-3688-6 ISSN 1745-6215.

Kwon, Joseph, Kim, Sung Wook, Ungar, Wendy J., Tsiplova, Kate, Madan, Jason and Petrou, Stavros (2019) Patterns, temporal trends and methodological associations in the measurement and valuation of childhood health utilities. Quality of Life Research, 28 . pp. 1705-1724. doi:10.1007/s11136-019-02121-z ISSN 0962-9343.

(2019) A protocol for a multi-site, spatially-referenced household survey in slum settings : methods for access, sampling frame construction, sampling, and field data collection. BMC Medical Research Methodology, 19 . 109. doi:10.1186/s12874-019-0732-x ISSN 1471-2288. [ 🗎 Public]. [ (✓) hoa:511 ]

Kumar, Meghan Bruce, Madan, Jason, Achieng, Maryline Mireku, Limato, Ralalicia, Ndima, Sozinho, Kea, Aschenaki Z., Chikaphupha, Kingsley Rex, Barasa, Edwine and Taegtmeyer, Miriam (2019) Is quality affordable for community health systems? Costs of integrating quality improvement into close-to-community health programmes in five low-income and middle-income countries. BMJ Global Health, 4 (4). e001390. doi:10.1136/bmjgh-2019-001390 ISSN 2059-7908. [ 🗎 Public]. [ (✓) hoa:511 ]

2018

Kim, Sung Wook, Madan, Jason, Dritsaki, Melina, Bryce, Carol, Forjaz, Vera, Fraser, Joe, Griffiths, Frances, Hamilton, Kathryn, Huxley, Caroline J. and Sturt, Jackie (2018) Benefits and costs of digital consulting in clinics serving young people with long-term conditions : mixed-methods approach. JMIR Medical Informatics, 6 (4). e48. doi:10.2196/medinform.9577 ISSN 2291-9694. [ (🔓): Yes ].

(2018) Recent advances in methodology for clinical trials in small populations : the InSPiRe project. Orphanet Journal of Rare Diseases, 13 (1). 186. doi:10.1186/s13023-018-0919-y ISSN 1750-1172. [ 🗎 Public]. [ (✓) hoa:511 ]

Melendez-Torres, G. J., Armoiry, Xavier, Court, Rachel A., Patterson, Jacoby, Kan, Alan, Auguste, Peter, Madan, Jason, Counsell, Carl, Ciccarelli, Olga and Clarke, Aileen (2018) Comparative effectiveness of beta-interferons and glatiramer acetate for relapsing-remitting multiple sclerosis : systematic review and network meta-analysis of trials including recommended dosages. BMC Neurology, 18 (1). doi:10.1186/s12883-018-1162-9 ISSN 1471-2377. [ 🗎 Public]. [ (✓) hoa:511 ]

Petrou, Stavros, Kwon, J. and Madan, Jason (2018) A practical guide to conducting a systematic review and meta-analysis of health state utility values. PharmacoEconomics, 36 (9). pp. 1043-1061. doi:10.1007/s40273-018-0670-1 ISSN 1170-7690. [ 🗎 Public]. [ (✓) hoa:511 ]

Duncan, Craig, Weich, Scott, Fenton, Sarah-Jane Hannah, Twigg, Liz, Moon, Graham, Madan, Jason, Singh, Swaran P., Crepaz-Keay, David, Parsons, Helen and Bhui, Kamaldeep (2018) A realist approach to the evaluation of complex mental health interventions. British Journal of Psychiatry, 213 (2). pp. 451-453. ISSN 0007-1250. [ 🗎 Public]. [ (✓) hoa:511 ]

Duncan, Craig, Weich, Scott, Fenton, Sarah-Jane, Twigg, Liz, Moon, Graham, Madan, Jason, Singh, Swaran P., Crepaz-Keay, David, Parsons, Helen and Bhui, Kamaldeep (2018) A realist approach to the evaluation of complex mental health interventions. The British Journal of Psychiatry, 213 (2). pp. 451-453. doi:10.1192/bjp.2018.96 ISSN 0007-1250.

Weich, Scott, Fenton, Sarah-Jane Hannah, Bhui, Kamaldeep, Staniszewska, Sophie, Madan, Jason, Larkin, Michael, Newton, Elizabeth, Crepaz-Keay, David, Canaway, Alastair, Croft, Charlotte and Griffiths, Frances (2018) Realist evaluation of the use of patient experience data to improve the quality of inpatient mental health care (EURIPIDES) in England : study protocol. BMJ Open, 8 (6). e021013. doi:10.1136/bmjopen-2017-021013 ISSN 2044-6055.

Achten, Juul, Vadher, Karan, Bruce, J. (Julie), Nanchahal, Jagdeep, Spoors, Louise, Masters, James P., Dutton, Susan, Madan, Jason and Costa, Matthew L. (2018) Standard wound management versus negative-pressure wound therapy in the treatment of adult patients having surgical incisions for major trauma to the lower limb — a two-arm parallel group superiority randomised controlled trial : protocol for Wound Healing in Surgery for Trauma (WHIST). BMJ Open, 8 (6). e022115. doi:10.1136/bmjopen-2018-022115 ISSN 2044-6055. [ 🗎 Public]. [ (✓) hoa:511 ]

MILESTONE Consortium (Including: Tuomainen, Helena, Schulze, Ulrike, Warwick, Jane, Paul, Moli, Dieleman, Gwen, Franić, Tomislav, Madan, Jason, Maras, Athanasios, McNicholas, Fiona, Purper-Ouakil, Diane, Santosh, Paramala, Signorini, Giulia, Street, Catherine, Tremmery, Sabine, Verhulst, Frank C., Wolke, Dieter and Singh, Swaran P.). (2018) Managing the link and strengthening transition from child to adult mental health care in Europe (MILESTONE) : background, rationale and methodology. BMC Psychiatry, 18 . 167. doi:10.1186/s12888-018-1758-z ISSN 1471-244X.

Miller, Frank, Zohar, Sarah, Stallard, Nigel, Madan, Jason, Posch, Martin, Hee, Siew Wan, Pearce , Michael, Vågerö, Mårten and Day, Simon (2018) Approaches to sample size calculation for clinical trials in rare diseases. Pharmaceutical Statistics, 17 (3). pp. 214-230. doi:10.1002/pst.1848 ISSN 1539-1604. [ 🗎 Public]. [ (✓) hoa:511 ]

Armoiry, Xavier, Kanda, Akira, Melendez-Torres, G. J., Court, Rachel A., Sutcliffe, P. (Paul), Auguste, Peter, Madan, Jason, Counsell, C. and Clarke, Aileen (2018) Short- and long-term clinical outcomes of use of beta-interferon or glatiramer acetate for people with clinically isolated syndrome : a systematic review of randomised controlled trials and network meta-analysis. Journal of Neurology, 265 (5). pp. 999-1009. doi:10.1007/s00415-018-8752-8 ISSN 0340-5354. [ (✓) hoa:511 ]

Kwon, J., Kim, Sung Wook, Ungar, W. J., Tsiplova , K., Madan, Jason and Petrou, Stavros (2018) A systematic review and meta-analysis of childhood health utilities. Medical Decision Making, 38 (3). pp. 277-305. doi:10.1177/0272989X17732990 ISSN 0272-989X. [ 🗎 Public].

(2018) The role of digital communication in patient-clinician communication for NHS providers of specialist clinical services for young people (The LYNC study) : a mixed methods study. Health Services and Delivery Research, 6 (9). doi:10.3310/hsdr06090 ISSN 2050-4349. [ (🔓): Yes ].

Pearce, Michael, Hee, Siew Wan, Madan, Jason, Posch, Martin, Day, Simon, Miller, Frank, Zohar, Sarah and Stallard, Nigel (2018) Value of information methods to design a clinical trial in a small population to optimise a health economic utility function. BMC Medical Research Methodology, 18 (1). p. 20. doi:10.1186/s12874-018-0475-0 ISSN 1471-2288. [ 🗎 Public]. [ (✓) hoa:511 ]

Vetrini, Damir, Kiire, Christine A., Burgess, Philip I. , Harding, Simon P., Kayange, Petros C., Kalua, Khumbo, Msukwa, Gerald, Beare, Nicholas A. V. and Madan, Jason (2018) Incremental cost-effectiveness of screening and laser treatment for diabetic retinopathy and macular edema in Malawi. PLoS One, 13 (1). e0190742. doi:10.1371/journal.pone.0190742 ISSN 1932-6203. [ 🗎 Public].

2017

(2017) Protocol for a cohort study of adolescent mental health service users with a nested cluster randomised controlled trial to assess the clinical and cost-effectiveness of managed transition in improving transitions from child to adult mental health services (the MILESTONE study). BMJ Open, 7 (10). e016055. doi:10.1136/bmjopen-2017-016055 ISSN 2044-6055. [ 🗎 Public].

Melendez-Torres, G. J., Auguste, Peter, Armoiry, Xavier, Maheswaran, H., Court, Rachel A., Madan, Jason, Kan, A., Lin, S., Counsell, C., Patterson, J., Rodrigus, J., Ciccarelli, O., Fraser, Hannah and Clarke, Aileen (2017) Clinical and cost-effectiveness of beta interferon and glatiramer acetate for treating multiple sclerosis : systematic review and economic evaluation. Health Technology Assessment, 21 (52). doi:10.3310/hta21520 ISSN 1366-5278. [ (🔓): Yes ].

Melendez-Torres, GJ, Auguste, Peter, Armoiry, Xavier, Maheswaran, Hendramoorthy, Court, Rachel A., Madan, Jason, Kan, Alan, Lin, Stephanie, Counsell, Carl, Patterson, Jacoby, Rodrigues, Jeremy, Ciccarelli, Olga, Fraser, Hannah and Clarke, Aileen (2017) Clinical effectiveness and cost-effectiveness of beta-interferon and glatiramer acetate for treating multiple sclerosis: systematic review and economic evaluation. Health Technology Assessment, 21 (52). pp. 1-352. doi:10.3310/hta21520 ISSN 1366-5278.

Stallard, Nigel, Miller, Frank, Day, Simon, Hee, Siew Wan, Madan, Jason, Zohar, Sarah and Posch, Martin (2017) Determination of the optimal sample size for a clinical trial accounting for the population size. Biometrical Journal, 59 (4). pp. 609-625. doi:10.1002/bimj.201500228 ISSN 0323-3847. [ 🗎 Public].

Madan, Jason, Khan, Kamran, Petrou, Stavros and Lamb, S. E. (Sallie E.) (2017) Can mapping algorithms based on raw scores overestimate QALYs gained by treatment? A comparison of mappings between the Roland–Morris Disability Questionnaire and the EQ-5D-3L based on raw and Differenced Score Data. PharmacoEconomics, 35 (5). pp. 549-559. doi:10.1007/s40273-016-0483-z ISSN 1170-7690. [ 🗎 Public]. [ (✓) hoa:511 ]

Griffiths, Frances, Bryce, Carol, Cave, Jonathan A. K., Dritsaki, Melina, Fraser, Joseph, Hamilton, Kathryn, Huxley, Caroline J., Ignatowicz, Agnieszka, Kim, Sung Wook, Kimani, Peter K., Madan, Jason, Slowther, Anne, Sujan, Mark-Alexander and Sturt, Jackie (2017) Timely digital patient-clinician communication in specialist clinical services for young people : a mixed-methods study (the LYNC study). Journal of Medical Internet Research, 19 (4). e102. doi:10.2196/jmir.7154 ISSN 1438-8871. [ 🗎 Public]. [ (🔓): Yes ].

Parker, Benjamin A., Madan, Jason, Petrou, Stavros and Underwood, Martin (2017) Can care staff accurately assess health-related quality of life of care home residents ? A secondary analysis of data from the OPERA trial. BMJ Open, 7 (4). e012779. doi:10.1136/bmjopen-2016-012779 ISSN 2044-6055. [ (🔓): Yes ].

Hee, Siew Wan, Willis, Adrian, Tudur Smith, Catrin, Day, Simon, Miller, Frank, Madan, Jason, Posch, Martin, Zohar, Sarah and Stallard, Nigel (2017) Does the low prevalence affect the sample size of interventional clinical trials of rare diseases? An analysis of data from the aggregate analysis of clinicaltrials.gov. Orphanet Journal of Rare Diseases, 12 (44). doi:10.1186/s13023-017-0597-1 ISSN 1750-1172. [ 🗎 Public].

Shiri, Tinevimbo, Datta, Samik, Madan, Jason, Tsertsvadze, Alexander, Royle, Pamela, Keeling, Matthew James, McCarthy, Noel D. and Petrou, Stavros (2017) Indirect effects of childhood pneumococcal conjugate vaccination on invasive pneumococcal disease: a systematic review and meta-analysis. Lancet Global Health, 5 (1). E51-E59. doi:10.1016/S2214-109X(16)30306-0 ISSN 2214-109X. [ 🗎 Public]. [ (✓) hoa:511 ]

2016

Gama, Elvis, Madan, Jason, Langley, Ivor, Girma, Mamo, Evans, Denise, Rosen, Sydney and Squire, S Bertel (2016) Economic evaluation of a shortened standardised treatment regimen of antituberculosis drugs for patients with multidrug-resistant tuberculosis (STREAM) : study protocol. BMJ Open, 6 (10). e014386. doi:10.1136/bmjopen-2016-014386 ISSN 2044-6055. [ 🗎 Public].

Naidoo, P., Dunbar, R., du Toit, E., van Niekerk, M., Squire, S. B., Beyers, N. and Madan, Jason (2016) Comparing laboratory costs of smear/culture and Xpert(®) MTB/RIF-based tuberculosis diagnostic algorithms. The International Journal of Tuberculosis and Lung Disease, 20 (10). pp. 1377-1385. doi:10.5588/ijtld.16.0081 ISSN 1815-7920. [ 🗎 Public].

Naidoo, P., Dunbar, R., Du Toit, E., Van Niekerk, M., Squire, S. B., Beyers, N. and Madan, Jason (2016) Comparing laboratory costs of smear/culture and Xpert® MTB/RIF-based tuberculosis diagnostic algorithms. The International Journal of Tuberculosis and Lung Disease, 20 (10). 1377-1385(9). doi:10.5588/ijtld.16.0081 ISSN 1815-7920.

Johnson, Rebecca E., Jenkinson, David J., Stinton, Chris, Taylor-Phillips, Sian, Madan, Jason, Stewart-Brown, Sarah L. and Clarke, Aileen (2016) Where’s WALY? : A proof of concept study of the ‘wellbeing adjusted life year’ using secondary analysis of cross-sectional survey data. Health and Quality of Life Outcomes, 14 (1). doi:10.1186/s12955-016-0532-5 ISSN 1477-7525. [ 🗎 Public].

Patel, Shilpa, Hee, Siew Wan, Mistry, Dipesh, Jordan, Jake, Brown, S., Dritsaki, Melina, Ellard, David R., Friede, Tim, Lamb, S. E., Lord, Joanne, Madan, Jason, Morris, Tom, Stallard, Nigel, Tysall, Colin, Willis, Adrian and Underwood, Martin (2016) Identifying back pain subgroups : developing and applying approaches using individual patient data collected within clinical trials. Programme Grants for Applied Research, 4 (10). doi:10.3310/pgfar04100 ISSN 2050-4322.

Hee, Siew Wan, Hamborg, Thomas, Day, Simon, Madan, Jason, Miller, F., Posch, Martin, Zohar, Sarah and Stallard, Nigel (2016) Decision-theoretic designs for small trials and pilot studies : a review. Statistical methods in medical research, 25 (3). pp. 1022-1038. doi:10.1177/0962280215588245 ISSN 0962-2802. [ 🗎 Public].

Rafia, Rachid, Brennan, Alan, Madan, Jason, Collins, Karen, Reed, Malcolm W.R., Lawrence, Gill, Robinson, Thompson, Greenberg, David and Wyld, Lynda (2016) Modeling the cost-effectiveness of alternative upper age limits for breast cancer screening in England and Wales. Value in Health, 19 (4). pp. 404-412. doi:10.1016/j.jval.2015.06.006 ISSN 1098-3015.

Auguste, Peter, Tsertsvadze, Alexander, Pink, Joshua, Court, Rachel A., Seedat, Farah, Gurung, Tara, Freeman, Karoline, Taylor-Phillips, Sian, Walker, Clare, Madan, Jason, Kandala, Ngianga-Bakwin, Clarke, Aileen and Sutcliffe, P. (Paul) (2016) Accurate diagnosis of latent tuberculosis in children, people who are immunocompromised or at risk from immunosuppression and recent arrivals from countries with a high incidence of tuberculosis : systematic review and economic evaluation. Health Technology Assessment, 20 (38). pp. 1-678. doi:10.3310/hta20380 ISSN 1366-5278. [ (🔓): Yes ].

Weller, Carolina D., Barker, Anna, Darby, Ian, Haines, Terrence, Underwood, Martin, Ward, Stephanie, Aldons, Pat, Dapiran, Elizabeth, Madan, Jason, Loveland, Paula, Sinha, Sankar, Vicaretti, Mauro, Wolfe, Rory, Woodward, Michael and McNeil, John (2016) Aspirin in venous leg ulcer study (ASPiVLU) : study protocol for a randomised controlled trial. Trials, 17 (1). 192. doi:10.1186/s13063-016-1314-4 ISSN 1745-6215.

Taylor-Phillips, Sian, Freeman, Karoline, Geppert, Julia, Agbebiyi, Adeola, Uthman, Olalekan A., Madan, Jason, Clarke, Angus, Quenby, Siobhan and Clarke, Aileen (2016) Accuracy of non-invasive prenatal testing using cell-free DNA for detection of Down, Edwards and Patau syndromes : a systematic review and meta-analysis. BMJ Open, 6 (1). e010002. doi:10.1136/bmjopen-2015-010002 ISSN 2044-6055. [ 🗎 Public]. [ (✓) hoa:511 ]

2015

Squire, S. B., Thomson, R., Namakhoma, I., El Sony, A., Kritski, A. and Madan, Jason (2015) Catastrophic care-seeking costs as an indicator for lung health. BMC Proceedings, 9 (Supplement 10). S4. doi:10.1186/1753-6561-9-S10-S4 ISSN 1753-6561.

Madan, Jason, Ades, Tony, Barton, Pelham , Bojke, Laura, Choy, Ernest, Helliwell, Philip, Jobanputra, Paresh , Stein, Ken, Stevens, Andrew, Tosh, Jonathan, Verstappen, Suzanne and Wailoo, Allan J. (2015) Consensus decision models for biologics in rheumatoid and psoriatic arthritis : recommendations of a multidisciplinary working party. Rheumatology and Therapy, 2 (2). pp. 113-125. doi:10.1007/s40744-015-0020-0 ISSN 2198-6576. [ 🗎 Public].

Banda, H. T., Mortimer, K., Bello, G. A. F., Mbera, G. B., Namakhoma, I., Thomson, R., Nyirenda, M. J., Faragher, B., Madan, Jason, Malmborg, R., Stenberg, B., Mpunga, J., Mwagomba, B., Gama, E., Piddock, K. and Squire, S. B. (2015) Informal health provider and practical approach to lung health interventions to improve the detection of chronic airways disease and tuberculosis at primary care level in Malawi : study protocol for a randomised controlled trial. Trials, 16 (1). doi:10.1186/s13063-015-1068-4 ISSN 1745-6215.

Madan, Jason, Lönnroth, Knut, Laokri, Samia and Squire, Stephen Bertel (2015) What can dissaving tell us about catastrophic costs? Linear and logistic regression analysis of the relationship between patient costs and financial coping strategies adopted by tuberculosis patients in Bangladesh, Tanzania and Bangalore, India. BMC Health Services Research, 15 (1). 476. doi:10.1186/s12913-015-1138-z ISSN 1472-6963. [ 🗎 Public].

Langley, Ivor, Squire, S. B., Dacombe, R., Madan, Jason, E Silva, J. R. L., Barreira, D., Galliez, R., Oliveira, M. M., Fujiwara, P. I. and Kritski, A. (2015) Developments in impact assessment of new diagnostic algorithms for tuberculosis control. Clinical Infectious Diseases, 61 (Issue suppl_3). S126-S134. doi:10.1093/cid/civ580 ISSN 1058-4838.

Griffiths, Frances, Atherton, Helen, Barker, Jack R., Cave, Jonathan A. K., Dennick, Kathryn, Dowdall, Peter, Fraser, Joe, Huxley, Caroline J., Sung -Wook, Kim, Madan, Jason, Matharu, Harjit, Musumadi, Luhanga, Palmer, Tom M., Paul, Moli, Sankaranarayanan, Sailesh, Slowther, Anne, Sujan, Mark-Alexander, Sutcliffe, Paul and Sturt, Jackie (2015) Improving health outcome for young people with long term conditions : the role of digital communication in current and future patient-clinician communication for NHS providers of specialist clinical services for young people receiving specialist clinical services - LYNC study protocol. Digital Health . pp. 1-13. doi:10.1177/2055207615593698 ISSN 2055-2076.

du Toit, E., Squire, S. B., Dunbar, R., Machekano, R., Madan, Jason, Beyers, N. and Naidoo, P. (2015) Comparing multidrug-resistant tuberculosis patient costs under molecular diagnostic algorithms in South Africa. The international journal of tuberculosis and lung disease, 19 (8). pp. 960-968. doi:10.5588/ijtld.14.0703 ISSN 1815-7920. [ 🗎 Public].

Khan, Kamran A., Madan, Jason, Petrou, Stavros and Lamb, S. E. (Sallie E.) (2015) Mapping between the Roland Morris Questionnaire and generic preference-based measures. Value in Health, 17 (6). pp. 686-695. doi:10.1016/j.jval.2014.07.001 ISSN 1098-3015.

2014

Gama, E., Madan, Jason, Banda, H., Squire, B., Thomson, R. and Namakhoma, I. (2014) Economic evaluation of the practical approach to lung health and informal provider interventions for improving the detection of tuberculosis and chronic airways disease at primary care level in Malawi : study protocol for cost-effectiveness analysis. Implementation Science, 10 (1). doi:10.1186/s13012-014-0195-8 ISSN 1748-5908.

Soares, Marta O., Welton, Nicky J., Harrison, David A., Peura, Piia, Shankar-Hari, Manu, Harvey, Sheila E, Madan, Jason, Ades, Anthony E., Rowan, Kathryn M. and Palmer, Stephen J. (2014) Intravenous immunoglobulin for severe sepsis and septic shock : clinical effectiveness, cost-effectiveness and value of a further randomised controlled trial. Critical Care Medicine, 18 (6). 649. doi:10.1186/s13054-014-0649-z ISSN 1530-0293. [ 🗎 Public].

Khan, Kamran A., Madan, Jason, Petrou, Stavros and Lamb, S. E. (Sallie E.) (2014) Mapping between the Roland Morris Questionnaire and generic preference-based measures. Value in Health, Volume 17 (Number 6). pp. 686-695. doi:10.1016/j.jval.2014.07.001 ISSN 1098-3015.

Nunn, Andrew J., Rusen, I. D., Van Deun, Armand, Torrea, Gabriela, Phillips, P. (Patrick), Chiang, Chen-Yuan, Squire, Stephen Bertel, Madan, Jason and Meredith, Sarah K. (2014) Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM) : study protocol for a randomized controlled trial. Trials, Volume 15 (Number 1). Article number 353. doi:10.1186/1745-6215-15-353 ISSN 1745-6215. [ 🗎 Public].

Madan, Jason, Chen, Y-F.‏‎, Aveyard, Paul, Wang, Dechao, Yahaya, Ismail, Munafo, Marcus, Bauld, Linda and Welton, Nicky (2014) Synthesis of evidence on heterogeneous interventions with multiple outcomes recorded over multiple follow-up times reported inconsistently : a smoking cessation case-study. Journal of the Royal Statistical Society: Series A (Statistics in Society) , Volume 177 (Number 1). pp. 295-314. doi:10.1111/rssa.12018 ISSN 0964-1998.

Welton, N., Madan, Jason, Caldwell, Darren, Peters, T. J. and Ades, A. E. (2014) Expected value of sample information for multi-arm cluster randomized trials with binary outcomes. Medical Decision Making, 34 (3). pp. 352-365. doi:10.1177/0272989X13501229 ISSN 0272-989X.

2013

Ades, A. E., Lu, G. and Madan, Jason (2013) Which health-related quality-of-life outcome when planning randomized trials : disease-specific or generic, or both? A common factor model. Value in Health, 16 (1). 185- 194. doi:10.1016/j.jval.2012.09.012 ISSN 1098-3015.

2012

Soares, M. O., Welton, N. J., Harrison, D. A., Peura, P., Hari, M. S., Harvey, S. E., Madan, Jason, Ades, A. E., Palmer, S. J. and Rowan, K. M. (2012) An evaluation of the feasibility, cost and value of information of a multicentre randomised controlled trial of intravenous immunoglobulin for sepsis (severe sepsis and septic shock) : incorporating a systematic review, metaanalysis and value of information analysis. Health Technology Assessment, 16 (7). doi:10.3310/hta16070 ISSN 1366-5278.

Chen, Y-F.‏‎, Madan, Jason, Welton, N., Yahaya, I., Aveyard, P., Bauld, L., Wang, D., Fry-Smith, A. and Munafò, M. R. (2012) Effectiveness and cost-effectiveness of computer and other electronic aids for smoking cessation : a systematic review and network meta-analysis. Health technology assessment (Winchester, England), Vol.16 (No.38). 1-205, iii. doi:10.3310/hta16380 ISSN 1366-5278.

2011

Welton, N. J., Madan, Jason and Ades, A. E. (2011) Are head-to-head trials of biologics needed? The role of value of information methods in arthritis research. Rheumatology, 50 (Supplement 4). iv19- iv25. doi:10.1093/rheumatology/ker242 ISSN 1462-0324.

Madan, Jason, Ades, A. E. and Welton, N. J. (2011) An overview of models used in economic analyses of biologic therapies for arthritis-from current diversity to future consensus. Rheumatology, 50 (Supplement 4). iv10- iv18. doi:10.1093/rheumatology/ker240 ISSN 1462-0324.

Madan, Jason, Stevenson, M. D., Cooper, K. L., Ades, A. E., Whyte, S. and Akehurst, R. (2011) Consistency between direct and indirect trial evidence : is direct evidence always more reliable? Value in Health, 14 (6). 953- 960. doi:10.1016/j.jval.2011.05.042 ISSN 1098-3015.

Ades, A. E., Madan, Jason and Welton, N. J. (2011) Indirect and mixed treatment comparisons in arthritis research. Rheumatology, 50 (Supplement 4). iv5- iv9. doi:10.1093/rheumatology/ker241 ISSN 1462-0324.

Vanni, T., Karnon, J., Madan, Jason, White, R. G., Edmunds, W. J., Foss, A. M. and Legood, R. (2011) Calibrating models in economic evaluation : a seven-step approach. PharmacoEconomics, 29 (1). 35- 49. doi:10.2165/11584600-000000000-00000 ISSN 1170-7690.

Walters, S. J., Winslow, M., Collins, K., Robinson, T., Green, T., Madan, Jason, Reed, M. W. R. and Wyld, L. (2011) Health care professionals' preferences for extending mammographic breast screening to the over 70s. Journal of Geriatric Oncology, 2 (1). 1- 10. doi:10.1016/j.jgo.2010.10.002 ISSN 1879-4068.

Whyte, Sophie, Cooper, Katy L., Stevenson, Matt D., Madan, Jason and Akehurst, Ron (2011) Cost-effectiveness of granulocyte colony–stimulating factor prophylaxis for febrile neutropenia in breast cancer in the United Kingdom. Value in Health, Vol.14 (No.4). pp. 465-474. doi:10.1016/j.jval.2010.10.037 ISSN 1098-3015.

Cooper, K. (Katy), Ph. D., Madan, Jason, Whyte, Sophie, Stevenson, M. (Matt) and Akehurst, Ron L. (2011) Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy : systematic review and meta-analysis. BMC Cancer, Volume 11 (Number 1). Article:404. doi:10.1186/1471-2407-11-404 ISSN 1471-2407. [ 🗎 Public].

2010

Tappenden, P., Saccardi, R., Confavreux, C., Sharrack, B., Muraro, P. A., Mancardi, G. L., Kozak, T., Farge-Bancel, D., Madan, Jason, Rafia, R., Akehurst, R. and Snowden, J. (2010) Autologous haematopoietic stem cell transplantation for secondary progressive multiple sclerosis : an exploratory cost-effectiveness analysis. Bone Marrow Transplantation, 45 (6). 1014- 1021. doi:10.1038/bmt.2009.305 ISSN 0268-3369 .

Collins, K., Winslow, M., Reed, M. W., Walters, S. J., Robinson, T., Madan, Jason, Green, T., Cocker, H. and Wyld, L. (2010) The views of older women towards mammographic screening : a qualitative and quantitative study. British Journal of Cancer, 102 (10). 1461- 1467. doi:10.1038/sj.bjc.6605662 ISSN 0007-0920.

Rajagopalan, B., Francis, J. M., Cooke, F., Korlipara, L. V. P., Blamire, A. M., Schapira, A. H. V., Madan, Jason, Neubauer, S. and Cooper, J. M. (2010) Analysis of the factors influencing the cardiac phenotype in Friedreich's ataxia. Movement Disorders, 25 (7). - 852. doi:10.1002/mds.22864 ISSN 0885-3185.

Madan, Jason, Rawdin, Andrew, Stevenson, Matt and Tappenden, Paul (2010) A rapid-response economic evaluation of the UK NHS Cancer Reform Strategy Breast Cancer Screening Program Extension via a plausible bounds approach. Value in Health, Vol.13 (No.2). pp. 215-221. doi:10.1111/j.1524-4733.2009.00667.x ISSN 1098-3015.

2009

Nixon, R. M., O'Hagan, A., Oakley, J., Madan, Jason, Stevens, J. W., Bansback, N. and Brennan, A. (2009) The rheumatoid arthritis drug development model : a case study in Bayesian clinical trial simulation. Pharmaceutical Statistics, 8 (4). pp. 371-389. doi:10.1002/pst.368 ISSN 1539-1604.

Tappenden, P., McCabe, C., Chilcott, J., Simpson, E., Nixon, R., Madan, Jason, Fisk, J. D. and Brown, M. (2009) Cost-effectiveness of disease-modifying therapies in the management of multiple sclerosis for the medicare population. Value in Health, 12 (5). 657 -665. doi:10.1111/j.1524-4733.2008.00485.x

Nixon, R. M., Bansback, N., Stevens, J. W., Brennan, A. and Madan, Jason (2009) Using short-term evidence to predict six-month outcomes in clinical trials of signs and symptoms in rheumatoid arthritis. Pharmaceutical Statistics, 8 (2). pp. 150-162. doi:10.1002/pst.351 ISSN 1539-1604.

2008

Campbell, M. J., Hall, D., Stephenson, T., Bacon, C. and Madan, Jason (2008) Recurrence rates for sudden infant death syndrome (SIDS) : the importance of risk stratification. Archives of Disease in Childhood, 93 (11). pp. 936-939. doi:10.1136/adc.2007.121350 ISSN 0003-9888.

Bansback, N., Brennan, A., Symmons, D., Nixon, R., Madan, Jason, Harrison, M. and Watson, K. (2008) Comment on : Modelling the cost effectiveness of TNF- α antagonists in the management of rheumatoid arthritis : results from the British Society for Rheumatology Biologics Registry : Reply. Rheumatology, 47 (7). p. 1107. doi:10.1093/rheumatology/ken173

2007

Karnon, J., Goyder, E., Tappenden, P., McPhie, S., Towers, I., Brazier, J. and Madan, Jason (2007) A review and critique of modelling in prioritising and designing screening programmes. Health Technology Assessment, 11 (52). doi:10.3310/hta11520

Brennan, A., Bansback, N., Nixon, R., Madan, Jason, Harrison, M., Watson, K. and Symmons, D. (2007) Modelling the cost effectiveness of TNF-α antagonists in the management of rheumatoid arthritis : Results from the British Society for Rheumatology Biologics Registry. Rheumatology, 46 (8). 1345- 1354. doi:10.1093/rheumatology/kem115 ISSN 1462-0324.

2006

O'Hagan, A., Stevenson, M. and Madan, Jason (2006) Monte Carlo probabilistic sensitivity analysis for patient level simulation models : efficient estimation of mean and variance using anova. Health Economics, 16 (10). 1009- 1023. doi:10.1002/hec.1199 ISSN 1057-9230.