2021

(2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy . doi:10.1080/15548627.2020.1797280 (In Press)

Jacomin, Anne-Claire, Gohel, Raksha, Hussain, Zunoon, Varga, Agnes, Maruzs, Tamas, Eddison, Mark, Sica, Margaux, Jain, Ashish, Moffat, Kevin G., Johansen, Terje, Jenny, Andreas, Juhasz, Gabor and Nezis, Ioannis P. (2021) Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila. Life Science Alliance, 4 (2). e202000965. doi:10.26508/lsa.202000965

2020

Petridi, Stavroula, Jacomin, Anne-Claire, Bhujabal, Zambarla, Johansen, Terje and Nezis, Ioannis P. (2020) Exploring selective autophagy in Drosophila : methods to identify Atg8-interacting proteins. In: Methods in Cell Biology. Elsevier. ISBN 0091-679X

Jacomin, Anne-Claire, Petridi, Stavroula, Di Monaco, Marisa and Nezis, Ioannis P. (2020) A nuclear role for Atg8-family proteins. Autophagy, 16 (9). pp. 1721-1723. doi:10.1080/15548627.2020.1794356

Jacomin, Anne-Claire, Petridi, Stavroula, Di Monaco, Marisa, Bhujabal, Zambarlal, Jain, Ashish, Mulakkal, Nitha Charles, Palara, Anthimi , Powell, Emma L., Chung, Bonita, Zampronio, Cleidiane, Jones, Alexandra M., Cameron, Alexander, Johansen, Terje and Nezis, Ioannis P. (2020) Regulation of expression of autophagy genes by Atg8a-interacting partners Sequoia, YL-1 and Sir2 in Drosophila. Cell Reports, 31 (8). 107695. doi:10.1016/j.cellrep.2020.107695

Sarkar, Sovan, Vaccaro, Maria I. and Nezis, Ioannis P. (2020) Editorial : Autophagy : from big data to physiological significance. Frontiers in Cell and Developmental Biology, 7 . 376. doi:10.3389/fcell.2019.00376

Gohel, Raksha, Kournoutis, Athanasios, Petridi, Stavroula and Nezis, Ioannis P. (2020) Molecular mechanisms of selective autophagy in Drosophila. International Review of Cell and Molecular Biology, 354 . pp. 63-105. doi:10.1016/bs.ircmb.2019.08.003

Jacomin, Anne-Claire and Nezis, Ioannis P. (2020) Selective autophagic degradation of the IKK complex in Drosophila is mediated by Kenny/IKKy to control inflammation. Molecular & Cellular Oncology, 7 (1). 1682309 . doi:10.1080/23723556.2019.1682309

Chang, Kai, Kang, Ping, Liu, Ying, Huang, Kerui, Miao, Ting, Taylor, Erika, Sagona, Antonia P., Nezis, Ioannis P., Bodmer, Rolf, Ocorr, Karen and Bai, Hua (2020) TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2 Autophagy. Autophagy, 16 (10). pp. 1807-1822. doi:10.1080/15548627.2019.1704117

2019

Jacomin, Anne-Claire, Geraki, Kalotina, Tjendana-Tjhin, Vindy, Collingwood, Joanna F. and Nezis, Ioannis P. (2019) Impact of autophagy and ageing on iron load and ferritin in Drosophila brain. Frontiers in Cell and Developmental Biology, 7 . 142 . doi:10.3389/fcell.2019.00142

Jacomin, Anne-Claire, Petridi, Stavroula, DiMonaco, Marisa, Jain, Ashish, Bhujabal, Zambarlal, Mulakkal, Nitha Charles, Palara, Anthimi, Powell, Emma L., Chung, Bonita, Zampronio, Cleidiane G., Jones, Alexandra M., Cameron, Alexander, Johansen, Terje and Nezis, Ioannis P. (2019) Atg8a interacts with transcription factor Sequoia to control the expression of autophagy genes in Drosophila. Working Paper. Cold Spring Harbor: bioRXiv.

Sudhakar, Padhmanand, Claire-Jacomin, Anne, Hautefort, Isabelle, Samavedam, Siva, Fatemian, Koorosh, Ari, Eszter, Gul, Leila, Demeter, Amanda, Jones, Emily, Korcsmaros, Tamas and Nezis, Ioannis P. (2019) Targeted interplay between bacterial pathogens and host autophagy. Autophagy, 15 (9). pp. 1620-1633. doi:10.1080/15548627.2019.1590519

Tsapras, P., Jacomin, Anne-Claire and Nezis, Ioannis P. (2019) Assays to monitor mitophagy in Drosophila. In: Autophagy. Methods in Molecular Biology, 1880 . New York, NY: Humana Press, pp. 643-653. ISBN 9781493988723

2018

Jacomin, Anne-Claire, Gul, Lejla, Sudhakar, Padhmanand, Korcsmaros, Tamas and Nezis, Ioannis P. (2018) What we learned from big data for autophagy research. Frontiers in Cell and Developmental Biology, 6 . 92. doi:10.3389/fcell.2018.00092

2017

Tusco, Radu, Jacomin, Anne-Claire, Jain, Ashish, Penman, Bridget S., Bowitz Larsen, Kenneth, Johansen, Terje and Nezis, Ioannis P. (2017) Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses. Nature Communications, 8 . 1264 . doi:10.1038/s41467-017-01287-9

Jacomin, Anne-Claire, Samavedam, Siva, Charles, Hannah and Nezis, Ioannis P. (2017) iLIR@viral : a web resource for LIR motif-containing proteins in viruses. Autophagy, 13 (10). pp. 1782-1789. doi:10.1080/15548627.2017.1356978

Tsapras, Panagiotis and Nezis, Ioannis P. (2017) Caspase involvement in autophagy. Cell Death & Differentiation, 24 (8). pp. 1369-1379. doi:10.1038/cdd.2017.43

Jacomin, Anne-Claire and Nezis, Ioannis P. (2017) Assays to monitor aggrephagy in Drosophila brain. In: Turksen, K., (ed.) Autophagy in Differentiation and Tissue Maintenance. Methods in Molecular Biology, 1854 . New York, NY: Humana Press, pp. 147-157. ISBN 9781493987474

2016

Palara, Anthimi, Sagona, Antonia P. and Nezis, Ioannis P. (2016) Preparation of Drosophila follicles for transmission electron microscopy. In: Oogenesis : Methods and Protocols. Methods in Molecular Biology, 1457 . Springer, pp. 105-110. ISBN 9781493937936

Jacomin, Anne-Claire and Nezis, Ioannis P. (2016) Using fluorescent reporters to monitor autophagy in the female germline cells in Drosophila melanogaster. In: Oogenesis : Methods and Protocols. Springer, pp. 69-78. ISBN 9781493937936

Jacomin, Anne-Claire, Samavedam, Siva, Promponas, Vasilis and Nezis, Ioannis P. (2016) iLIR database : a web resource for LIR motif-containing proteins in eukaryotes. Autophagy, 12 (10). pp. 1945-1953. doi:10.1080/15548627.2016.1207016

Tsapras, Panagiotis , Sagona, Antonia P. and Nezis, Ioannis P. (2016) Immuno-gold labeling of Drosophila follicles for transmission electron microscopy. In: Oogenesis : Methods and Protocols. Methods in Molecular Biology, 1457 . Springer, pp. 97-103. ISBN 9781493937936

(2016) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 12 (1). pp. 1-222. doi:10.1080/15548627.2015.1100356

2015

Eikenes, Åsmund H., Malerød, Lene, Christensen, Anette Lie, Steen, Chloé B., Mathieu, Juliette, Nezis, Ioannis P., Liestøl, Knut, Huynh, Jean-René, Stenmark, H. and Haglund, Kaisa (2015) ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo. PLoS Genetics, Volume 11 (Number 1). pp. 1-7. Article number e1004904. doi:10.1371/journal.pgen.1004904

2014

Nezis, I. P., Vaccaro, Maria I., Devenish, Rodney J. and Juhász, Gábor (2014) Autophagy in development, cell differentiation, and homeodynamics: from molecular mechanisms to diseases and pathophysiology. BioMed Research International, Volume 2014 . pp. 1-2. Article number 349623. doi:10.1155/2014/349623

Mulakkal, Nitha Charles, Nagy, Péter, Takats, Szabolcs, Tusco, Radu, Juhász, Gábor and Nezis, I. P. (2014) Autophagy in Drosophila : from historical studies to current knowledge. BioMed Research International, 2014 . 273473. doi:10.1155/2014/273473

Kalvari, Ioanna, Tsompanis, Stelios, Mulakkal, Nitha Charles, Osgood, Richard, Johansen, Terje, Nezis, I. P. and Promponas, Vasilis J. (2014) iLIR : a web resource for prediction of Atg8-family interacting proteins. Autophagy, Volume 10 (Number 5). doi:10.4161/auto.28260

Sagona, Antonia P., Nezis, Ioannis P. and Stenmark, H. (Harald) (2014) Association of CHMP4B and autophagy with micronuclei : implications for cataract formation. BioMed Research International, Volume 2014 . Article number 974393. doi:10.1155/2014/974393

2013

Eskelinen, Eeva-Liisa , Liton, Paloma B., Nezis, I. P. and Piacentini, Mauro (2013) Autophagy researchers. Autophagy, Volume 9 (Number 10). pp. 1451-1454. doi:10.4161/auto.25877

Shultz, Sebastian Wolfgang, Brech, Andreas and Nezis, I. P. (2013) Time flies : autophagy during ageing in Drosophila. In: Bailly, Yannick, (ed.) Autophagy : a double-edged sword : cell survival or death? Croatia: In-Tech. ISBN 9789535110620

2012

Nezis, I. P. (2012) The selectivity and specificity of autophagy in drosophila. Cells, Volume 1 (Number 3). pp. 248-262. doi:10.3390/cells1030248

(2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, Vol.8 (No.4). pp. 445-544. doi:10.4161/auto.19496

Nezis, I. P. (2012) Selective Autophagy in Drosophila. International Journal of Cell Biology, Vol. 2012 . pp. 1-9. doi:10.1155/2012/146767

Nezis, I. P. and Stenmark, H. (Harald) (2012) p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer. Antioxidants & Redox Signaling, Vol. 17 (No. 5). pp. 786-793. doi:10.1089/ars.2011.4394

2011

Bartlett, Bryan J., Isakson, Pauline, Lewerenz, Jan, Sanchez, Heriberto, Kotzebue, Roxanne W., Cumming, Robert C., Harris, Greg L., Nezis, I. P., Schubert, David R., Simonsen, Anne and Finley, Kim D. (2011) Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects. Autophagy, Vol. 7 (No. 6). pp. 572-583. doi:10.4161/auto.7.6.14943

Haglund, Kaisa, Nezis, I. P. and Stenmark, H. (Harald) (2011) Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development. Communicative & Integrative Biology, Vol. 4 (No. 1). pp. 1-9. doi:10.4161/cib.4.1.13550

Sagona, Antonia P., Nezis, I. P., Bache, Kristi G., Haglund, Kaisa, Bakken, Anne Cathrine, Skotheim, Rolf I. and Stenmark, H. (Harald) (2011) A Tumor-Associated Mutation of FYVE-CENT Prevents Its Interaction with Beclin 1 and Interferes with Cytokinesis. PLoS ONE, Vol. 6 (No. 3). e17086. doi:10.1371/journal.pone.0017086

2010

Nezis, I. P., Sagona, Antonia P., Schink, Kay Oliver and Stenmark, H. (Harald) (2010) Divide and ProsPer : the emerging role of PtdIns3P in cytokinesis. Trends in Cell Biology, Volume 20 (Number 11). pp. 642-649. doi:10.1016/j.tcb.2010.08.010

Nezis, I. P., Shravage, Bhupendra V., Sagona, Antonia P., Lamark, Trond, Bjorkoy, G., Johansen, Terje, Rusten, Tor Erik, Brech, Andreas, Baehrecke, Eric H. and Stenmark, H. (Harald) (2010) Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. The Journal of Cell Biology, Vol. 190 (No. 4). pp. 523-531. doi:10.1083/jcb.201002035

Malagoli, Davide, Abdalla, Fabio C., Cao, Yang, Feng, Qili, Fujisaki, Kozo, Gregorc, Ales, Matsuo, Tomohide, Nezis, I. P., Papassideri, Issidora S., Sass, Miklós, Silva-Zacarin, Elaine C. M., Tettamanti, Gianluca and Umemiya-Shirafuji, Rika (2010) Autophagy and its physiological relevance in arthropods: Current knowledge and perspectives. Autophagy, Vol. 6 (No. 5). pp. 575-588. doi:10.4161/auto.6.5.11962

Nezis, I. P., Shravage, Bhupendra V., Sagona, Antonia P., Johansen, Terje, Baehrecke, Eric H. and Stenmark, H. (Harald) (2010) Autophagy as a trigger for cell death : autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila. Autophagy, Vol. 6 (No. 8). pp. 1214-1215. doi:10.4161/auto.6.8.13694

(2010) CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice. The EMBO Journal, Vol. 29 (No. 14). pp. 2421-2432. doi:10.1038/emboj.2010.120

Haglund, Kaisa, Nezis, I. P., Lemus, Dafne, Grabbe, Caroline, Wesche, Jørgen, Liestøl, Knut, Dikic, Ivan, Palmer, Ruth and Stenmark, H. (Harald) (2010) Cindr Interacts with Anillin to Control Cytokinesis in Drosophila melanogaster. Current Biology, Vol. 20 (No. 10). pp. 944-950. doi:10.1016/j.cub.2010.03.068

Nezis, I. P., Sagona, Antonia P., Schink, Kay Oliver and Stenmark, H. (Harald) (2010) Divide and ProsPer: The emerging role of PtdIns3P in cytokinesis. Trends in Cell Biology, Vol. 20 (No. 11). pp. 642-649. doi:10.1016/j.tcb.2010.08.010

Sagona, Antonia P., Nezis, I. P., Pedersen, Nina Marie, Liestøl, Knut, Poulton, John, Rusten, Tor Erik, Skotheim, Rolf I., Raiborg, Camilla and Stenmark, H. (Harald) (2010) PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. Nature Cell Biology, Vol. 12 (No. 4). pp. 362-371. doi:10.1038/ncb2036

2009

Vaccari, Thomas, Rusten, Tor Erik, Menut, L., Nezis, I. P., Brech, Andreas, Stenmark, H. (Harald) and Bilder, David (2009) Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants. Journal of Cell Science, Volume 122 (Number 14). pp. 2413-2423. doi:10.1242/jcs.046391

Nezis, I. P., Lamark, Trond, Velentzas, Athanassios D., Rusten, Tor Erik, Bjørkøy, Geir, Johansen, Terje, Papassideri, Issidora S., Stravopodis, Dimitrios J., Margaritis, Lukas H., Stenmark, H. (Harald) and Brech, Andreas (2009) Cell death duringDrosophila melanogasterearly oogenesis is mediated through autophagy. Autophagy, Vol. 5 (No. 3). pp. 298-303. doi:10.4161/auto.5.3.7454

2008

Nezis, I. P. and Papassideri, Issidora (2008) Chapter Thirty‐Seven Monitoring Autophagy in Insect Eggs. Methods in Enzymology, Vol. 451 . pp. 669-683. doi:10.1016/s0076-6879(08)03237-0

Mpakou, Vicky E., Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2008) Different modes of programmed cell death during oogenesis of the silkmoth Bombyx mori. Autophagy, Vol. 4 (No. 1). pp. 97-100.

Nezis, I. P., Simonsen, Anne, Sagona, Antonia P., Finley, Kim D., Gaumer, S., Contamine, D., Rusten, Tor Erik, Stenmark, H. (Harald) and Brech, Andreas (2008) Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain. The Journal of Cell Biology, Vol. 180 (No. 6). pp. 1065-1071. doi:10.1083/jcb.200711108

2007

Hatziantoniou, Sophia, Nezis, I. P., Margaritis, Lukas H. and Demetzos, Costas (2007) Visualisation of liposomes prepared from skin and stratum corneum lipids by transmission electron microscopy. Micron, Volume 38 (Number 8). pp. 777-781. doi:10.1016/j.micron.2007.06.005

Rusten, Tor Erik, Vaccari, Thomas, Lindmo, Karine, Rodahl, Lina M.W., Nezis, I. P., Sem-Jacobsen, Catherine, Wendler, Franz, Vincent, Jean-Paul, Brech, Andreas, Bilder, David and Stenmark, H. (Harald) (2007) ESCRTs and Fab1 regulate distinct steps of autophagy. Current Biology, Volume 17 (Number 20). pp. 1817-1825. doi:10.1016/j.cub.2007.09.032

Panagopoulos, Dimitris J., Chavdoula, Evangelia D., Nezis, I. P. and Margaritis, Lukas H. (2007) Cell death induced by GSM 900-MHz and DCS 1800-MHz mobile telephony radiation. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 626 (Number 1-2). pp. 69-78. doi:10.1016/j.mrgentox.2006.08.008

Velentzas, Athanassios D., Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S. and Margaritis, Lukas H. (2007) Apoptosis and autophagy function cooperatively for the efficacious execution of programmed nurse cell death during Drosophila virilis oogenesis. Autophagy, Volume 3 (Number 2). pp. 130-132. doi:10.4161/auto.3582

Velentzas, Athanassios D., Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S. and Margaritis, Lukas H. (2007) Stage-specific regulation of programmed cell death during oogenesis of the medfly Ceratitis capitata (Diptera, Tephritidae). The International Journal of Developmental Biology, Volume 51 (Number 1). pp. 57-66. doi:10.1387/ijdb.062164av

2006

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Chromatin condensation of ovarian nurse and follicle cells is regulated independently from DNA fragmentation during Drosophila late oogenesis. Differentiation, Volume 74 (Number 6). pp. 293-304. doi:10.1111/j.1432-0436.2006.00076.x

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Follicular atresia during Dacus oleae oogenesis. Journal of Insect Physiology, Volume 52 (Number 3). pp. 282-290. doi:10.1016/j.jinsphys.2005.11.007

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Programmed cell death of follicular epithelium during the late developmental stages of oogenesis in the fruit flies Bactrocera oleae and Ceratitis capitata (Diptera, Tephritidae) is mediated by autophagy. Development, Growth and Differentiation, Volume 48 (Number 3). pp. 189-198. doi:10.1111/j.1440-169X.2006.00856.x

Velentzas, Athanassios D., Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S. and Margaritis, Lukas H. (2006) Mechanisms of programmed cell death during oogenesis in Drosophila virilis. Cell and Tissue Research, Volume 327 (Number 2). pp. 399-414. doi:10.1007/s00441-006-0298-x

Nezis, I. P., Stravopodis, Dimitrios J., Margaritis, Lukas H. and Papassideri, Issidora S. (2006) Autophagy is required for the degeneration of the ovarian follicular epithelium in higher diptera. Autophagy, Volume 2 (Number 4). pp. 297-298. doi:10.4161/auto.2858

2005

Chondrogianni, N., Tzavelas, C., Pemberton, A. J., Nezis, I. P., Rivett, A. J. and Gonos, E. S. (2005) Overexpression of proteasome 5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates. Journal of Biological Chemistry, Volume 280 (Number 12). pp. 11840-11850. doi:10.1074/jbc.M413007200

Nezis, I. P., Stravopodis, Dimitrios J., Papassideri, Issidora S., Stergiopoulos, Costas and Margaritis, Lukas H. (2005) Morphological irregularities and features of resistance to apoptosis in thedcp-1/pita double mutated egg chambers during Drosophila oogenesis. Cell Motility and the Cytoskeleton, Volume 60 (Number 1). pp. 14-23. doi:10.1002/cm.20043

2003

Nezis, I. P., Modes, Vassilis, Mpakou, Vicky, Stravopodis, Dimitrios J., Papassideri, Issidora S., Mammali, Ioanna and Margaritis, Lukas H. (2003) Modes of programmed cell death during Ceratitis capitata oogenesis. Tissue and Cell , Volume 35 (Number 2). pp. 113-119. doi:10.1016/S0040-8166(03)00010-7

2002

Nezis, I. P., Stravopodis, Dimitrios, Papassideri, Issidora, Robert-Nicoud, Michel and Margaritis, Lukas (2002) Dynamics of apoptosis in the ovarian follicle cells during the late stages of Drosophila oogenesis. Cell and Tissue Research, Volume 307 (Number 3). pp. 401-409. doi:10.1007/s00441-001-0498-3

Sideratou, Zili, Foundis, John, Tsiourvas, Dimitris, Nezis, I. P., Papadimas, Georgios and Paleos, Constantinos M. (2002) A novel dendrimeric “glue” for adhesion of phosphatidyl choline-based liposomes. Langmuir, Volume 18 (Number 13). pp. 5036-5039. doi:10.1021/la020150i

2000

Nezis, I. P., Stravopodis, Dimitrios J. , Papassideri, Issidora S., Robert-Nicoud, Michel and Margaritis, Lukas H. (2000) Stage-specific apoptotic patterns during oogenesis. European Journal of Cell Biology, Volume 79 (Number 9). pp. 610-620. doi:10.1078/0171-9335-00088

1999

Xanthou, G., Tapinos, N. I., Polihronis, M., Nezis, I. P., Margaritis, L. H. and Moutsopoulos, H. M. (1999) CD4 cytotoxic and dendritic cells in the immunopathologic lesion of Sjögren's syndrome. Clinical & Experimental Immunology, Volume 118 (Number 1). pp. 154-163. doi:10.1046/j.1365-2249.1999.01037.x