2022

Mau, King Hang Tommy, Karimlou, Donja, Barneda, David, Brochard, Vincent, Royer, Christophe, Leeke, Bryony, de Souza, Roshni A., Pailles, Mélanie, Percharde, Michelle, Srinivas, Shankar, Jouneau, Alice, Christian, Mark and Azuara, Véronique (2022) Dynamic enlargement and mobilization of lipid droplets in pluripotent cells coordinate morphogenesis during mouse peri-implantation development. Nature Communications, 13 (1). 3861. doi:10.1038/s41467-022-31323-2

2020

Omran, Farah and Christian, Mark (2020) Inflammatory signaling and brown fat activity. Frontiers in Endocrinology, 11 . doi:10.3389/fendo.2020.00156

2018

Millership, Steven J., Tunster, Simon J., Pette, Mathew Van de, Choudhury, Agharul I., Irvine, Elaine E., Christian, Mark, Fisher, Amanda G., John, Rosalind M., Scott, James and Withers, Dominic J. (2018) Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice. Molecular Metabolism, 18 . pp. 97-106. doi:10.1016/j.molmet.2018.09.001

Christian, Mark (2018) In Vitro Models for Study of Brown Adipocyte Biology. Handbook of experimental pharmacology, 251 . Switzerland: Cham, pp. 85-96.

Liu, Yangli, Xu, Shimeng, Zhang, Congyan, Zhu, Xiaotong, Hammad, Mirza Ahmed, Zhang, Xuelin, Christian, Mark, Zhang, Hong and Liu, Pingsheng (2018) Hydroxysteroid dehydrogenase family proteins on lipid droplets through bacteria, C. elegans, and mammals. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1863 (8). pp. 881-894. doi:10.1016/j.bbalip.2018.04.018

(2018) Neuronatin regulates pancreatic β cell insulin content and secretion. Journal of Clinical Investigation . doi:10.1172/JCI120115

Schilperoort, Maaike, van Dam, Andrea D., Hoeke, Geerte, Shabalina, Irina G., Okolo, Anthony, Hanyaloglu, Aylin C., Dib, Lea H., Mol, Isabel M., Caengprasath, Natarin, Chan, Yi-Wah, Damak, Sami, Miller, Anne Reifel, Coskun, Tamer, Shimpukade, Bharat, Ulven, Trond, Kooijman, Sander, Rensen, Patrick C. N. and Christian, Mark (2018) The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. EMBO Molecular Medicine, 10 (3). e8047. doi:10.15252/emmm.201708047

2017

Barneda, David and Christian, Mark (2017) Lipid droplet growth : regulation of a dynamic organelle. Current Opinion in Cell Biology, 47 . pp. 9-15. doi:10.1016/j.ceb.2017.02.002

Hu, Jiamiao and Christian, Mark (2017) Hormonal factors in the control of the browning of white adipose tissue. Hormone Molecular Biology and Clinical Investigation, 31 (1). 20170017. doi:10.1515/hmbci-2017-0017

Irshad, Zehra, Dimitri, Federica, Christian, Mark and Zammit, Victor A. (2017) Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes. Journal of Lipid Research, 58 (1). pp. 15-30. doi:10.1194/jlr.M068197

2016

Blondrath, Katrin, Steel, Jennifer H., Katsouri, Loukia, Ries, Miriam, Parker, Malcolm G., Christian, Mark and Sastre, Magdalena (2016) The nuclear cofactor receptor interacting protein-140 (RIP140) regulates the expression of genes involved in Aβ generation. Neurobiology of Aging, 47 . pp. 180-191. doi:10.1016/j.neurobiolaging.2016.08.003

Brew, O., Nikolopoulou, E., Hughes, A., Christian, Mark, Lee, Y., Oduwole, O., Sullivan, M. H. F. and Woodman, Andrew (2016) Quality of placental RNA : effects of explant size and culture duration. Placenta, 46 . pp. 45-48. doi:10.1016/j.placenta.2016.08.083

Van De Pette, Matthew, Tunster, Simon J., McNamara, Grainne I., Shelkovnikova, Tatyana, Millership, Steven, Benson, Lindsay, Peirson, Stuart, Christian, Mark, Vidal-Puig, Antonio and John, Rosalind M. (2016) Cdkn1c boosts the development of brown adipose tissue in a murine model of Silver Russell syndrome. PLoS Genetics, 12 (3). e1005916. doi:10.1371/journal.pgen.1005916

Pisani, D. F., Beranger, G. E., Corinus, A., Giroud, M., Ghandour, R. A., Altirriba, J., Chambard, J.-C., Mazure, N. M., Bendahhou, S., Duranton, C., Michiels, J.-F., Frontini, A., Rohner-Jeanrenaud, F., Cinti, S., Christian, Mark, Barhanin, J. and Amri, E.-Z. (2016) The K+ channel TASK1 modulates -adrenergic response in brown adipose tissue through the mineralocorticoid receptor pathway. The FASEB Journal, 30 (2). pp. 909-922. doi:10.1096/fj.15-277475

Nawathe, Aamod R., Christian, Mark, Kim, Sung Hye, Johnson, Mark, Savvidou, Makrina D. and Terzidou, Vasso (2016) Insulin-like growth factor axis in pregnancies affected by fetal growth disorders. Clinical Epigenetics, 8 (1). 11. doi:10.1186/s13148-016-0178-5

2015

Barneda, David, Planas-Iglesias, Joan, Gaspar, Maria L., Mohammadyani, Dariush, Prasannan, Sunil, Dormann, Dirk, Han, Gil-Soo, Jesch, Stephen A., Carman, George M., Kagan, Valerian, Parker, Malcolm G., Ktistakis, Nicholas T., Klein-Seetharaman, Judith, Dixon, Ann M., Henry, Susan A. and Christian, Mark (2015) The brown adipocyte protein CIDEA promotes lipid droplet fusion via a phosphatidic acid-binding amphipathic helix. eLife, 4 . doi:10.7554/eLife.07485

Yu, Jinhai, Zhang, Shuyan, Cui, Liujuan, Wang, Weiyi, Na, Huimin, Zhu, Xiaotong, Li, Linghai, Xu, Guoheng, Yang, Fuquan, Christian, Mark and Liu, Pingsheng (2015) Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1853 (5). pp. 918-928. doi:10.1016/j.bbamcr.2015.01.020

2014

Parr, C., Mirzaei, N., Christian, Mark and Sastre, M. (2014) Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter. The FASEB Journal, 29 (2). pp. 623-635. doi:10.1096/fj.14-253211

Nikolopoulou, E., Papacleovoulou, G., Jean-Alphonse, F., Grimaldi, G., Parker, M. G., Hanyaloglu, A. C. and Christian, Mark (2014) Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential. The Journal of Lipid Research , Volume 55 (Number 12). pp. 2479-2490. doi:10.1194/jlr.M049551

Christian, Mark (2014) Transcriptional fingerprinting of "browning" white fat identifies NRG4 as a novel adipokine. Adipocyte, Volume 3 (Number 4). doi:10.4161/adip.29853

Rosell, M., Kaforou, Myrsini, Frontini, Andrea, Okolo, A., Chan, Yi-Wah, Nikolopoulou, E., Millership, S., Fenech, M. E., MacIntyre, D., Turner, J. O., Moore, Jonathan D., Blackburn, E., Gullick, W. J., Cinti, S., Montana, G., Parker, Malcolm G. and Christian, Mark (2014) Brown and white adipose tissues : intrinsic differences in gene expression and response to cold exposure in mice. AJP: Endocrinology and Metabolism, Volume 306 (Number 8). E945-E964. doi:10.1152/ajpendo.00473.2013

(2014) Uterine selection of human embryos at implantation. Scientific Reports, 4 . 3894. doi:10.1038/srep03894

Kiskinis, Evangelos, Chatzeli, Lemonia, Curry, Edward, Kaforou, Myrsini, Frontini, Andrea, Cinti, Saverio, Montana, Giovanni, Parker, Malcolm G. and Christian, Mark (2014) RIP140 represses the “Brown-in-White” adipocyte program including a futile cycle of triacyclglycerol breakdown and synthesis. Molecular Endocrinology, Volume 28 (Number 3). pp. 344-356. doi:10.1210/me.2013-1254

2013

Barneda, David, Frontini, Andrea, Cinti, Saverio and Christian, Mark (2013) Dynamic changes in lipid droplet-associated proteins in the “browning” of white adipose tissues. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1831 (5). pp. 924-933. doi:10.1016/j.bbalip.2013.01.015

Kuroda, Keiji, Venkatakrishnan, R., Salker, Madhuri S., Lucas, Emma S., Shaheen, Fozia, Kuroda, Masako, Blanks, Andrew M., Christian, Mark, Quenby, Siobhan and Brosens, Jan J. (2013) Induction of 11 -HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells. Molecular Endocrinology, Volume 27 (Number 2). pp. 192-202. doi:10.1210/me.2012-1247

Kuroda, Keiji, Venkatakrishnan, R., Salker, Madhuri S., Lucas, Emma S., Shaheen, Fozia, Blanks, Andrew M., Christian, Mark, Quenby, Siobhan and Brosens, Jan J. (2013) Induction of 11beta-hydroxysteroid dehydrogenase type 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells. Molecular Endocrinology, 27 (2). pp. 192-202.

Shah, Kunal M., Webber, Jason, Dr., Carzaniga, Raffaella, Taylor, Deborah M., Fusi, Luca, Clayton, Aled, Brosens, Jan J., Hartshorne, Geraldine M. and Christian, Mark (2013) Induction of microRNA resistance and secretion in differentiating human endometrial stromal cells. Journal of Molecular Cell Biology, Volume 5 (Number 1). pp. 67-70. doi:10.1093/jmcb/mjs058

Nautiyal, Jaya, Christian, Mark and Parker, Malcolm G. (2013) Distinct functions for RIP140 in development, inflammation, and metabolism. Trends in Endocrinology & Metabolism, Volume 24 (Number 9). pp. 451-459. doi:10.1016/j.tem.2013.05.001

2012

Salker, Madhuri S., Nautiyal, Jaya, Steel, Jennifer H., Webster, Zoe, Šućurović, Sandra, Nicou, Marilena, Singh, Yogesh, Dr., Lucas, Emma S., Murakami, Keisuke, Chan, Yi-Wah, James, Sean G., Abdallah, Yazan, Christian, Mark, Croy, B. A. (B. Anne), Mulac-Jericevic, Biserka, Quenby, Siobhan and Brosens, Jan J. (2012) Disordered IL-33/ST2 activation in decidualizing stromal cells prolongs uterine receptivity in women with recurrent pregnancy loss. PLoS One, Vol.7 (No.12). e52252. doi:10.1371/journal.pone.0052252

Virtue, Sam, Feldmann, Helena, Christian, Mark, Tan, Chong Yew, Masoodi, Mojgan, Dale, Martin, Lelliott, Chris, Burling, Keith, Campbell, Mark, Eguchi, Naomi, Voshol, Peter, Sethi, Jaswinder K., Parker, Malcolm G., Urade, Yoshihiro, Griffin, Julian L., Cannon, Barbara and Vidal-Puig, Antonio (2012) A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization. Diabetes, 61 (12). pp. 3139-3147. doi:10.2337/db12-0015

Lee, Yun, Sooranna, Suren R., Terzidou, Vasso, Christian, Mark, Brosens, Jan J., Huhtinen, Kaisa, Poutanen, Matti, Barton, Geraint, Johnson, Mark R. and Bennett, Phillip R. (2012) Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterine myocytes. Journal of Cellular and Molecular Medicine, 16 (10). pp. 2487-2503. jcmm0016-2487. doi:10.1111/j.1582-4934.2012.01567.x

Grimaldi, Giulia, Christian, Mark, Quenby, Siobhan and Brosens, Jan J. (2012) Expression of epigenetic effectors in decidualizing human endometrial stromal cells. Molecular Human Reproduction, Volume 18 (Number 9). pp. 451-458. doi:10.1093/molehr/gas020

2011

Grimaldi, Giulia, Christian, Mark, Steel, Jennifer H., Henriet, Patrick, Poutanen, Matti and Brosens, Jan J. (2011) Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells. Molecular Endocrinology, Vol.25 (No.11). pp. 1892-1903. doi:10.1210/me.2011-1139

Christian, Mark, Lam, Eric W.-F., Wilson, Miranda S. C. and Brosens, Jan J. (2011) FOXO transcription factors and their role in disorders of the female reproductive tract. Current Drug Targets, Vol.12 (No.9). pp. 1291-1302. doi:10.2174/138945011796150253

Salker, M. S., Christian, Mark, Steel, J. H., Nautiyal, J., Lang, F. and Brosens, Jan J. (2011) Deregulated activity of the serum and glucocorticoid-inducible kinase (SGK1) in the endometrium causes reproductive failure. Reproductive Sciences, Vol.18 (No.S3). 272A.

Al-Sabbagh, Marwa, Fusi, Luca, Higham, J., Lee, Y., Lei, Kaiyu, Hanyaloglu, A. C., Lam, Eric W. -F., Christian, Mark and Brosens, Jan J. (2011) NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling. Reproductive Sciences, Vol.18 (No.3(Supp)). 162A-162A. doi:10.1177/193371912011183s067

Al-Sabbagh, M., Fusi, L., Higham, J., Lee, Y., Lei, K., Hanyaloglu, A. C., Lam, E. W.- F., Christian, Mark and Brosens, Jan J. (2011) NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling. Endocrinology, Vol.152 (No.2). pp. 730-740. doi:10.1210/en.2010-0899

Salker, Madhuri S, Christian, Mark, Steel, Jennifer H, Nautiyal, Jaya, Lavery, Stuart, Trew, Geoffrey, Webster, Zoe, Al-Sabbagh, Marwa, Puchchakayala, Goverdhan, Föller, Michael, Landles, Christian, Sharkey, Andrew M, Quenby, Siobhan, Aplin, John D, Regan, Lesley, Lang, Florian and Brosens, Jan J. (2011) Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Nature Medicine, Vol.17 (No.11). pp. 1509-1513. doi:10.1038/nm.2498

2010

Cloke, Brianna, Shah, Kunal, Kaneda, Hiroshi, Lavery, Stuart, Trew, Geoffrey, Fusi, Luca, Higham, Jenny, Dina, Roberto E., Ghaem-Maghami, Sadaf, Ellis, Patricia, Brosens, Jan J. and Christian, Mark (2010) The Poly(C)-binding protein-1 regulates expression of the androgen receptor. Endocrinology, Vol.151 (No.8). pp. 3954-3964. doi:10.1210//en.2009-1264

Leitao, B., Jones, M. C., Fusi, L., Higham, J., Lee, Y., Takano, M., Goto, T., Christian, Mark, Lam, Eric W.-F. and Brosens, Jan J. (2010) Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals. FASEB Journal, Vol.24 (No.5). pp. 1541-1551. doi:10.1096/fj.09-149153

Myatt, Stephen S., Wang, J., Monteiro, L. J., Christian, Mark, Ho, K.-K., Fusi, L., Dina, R. E., Brosens, Jan J., Ghaem-Maghami, S. and Lam, Eric W.-F. (2010) Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer. Cancer Research, Vol.70 (No.1). pp. 367-377. doi:10.1158/0008-5472.CAN-09-1891

2008

Hallberg, M., Morganstein, D. L., Kiskinis, E., Shah, K., Kralli, A., Dilworth, S. M., White, R., Parker, M. G. and Christian, Mark (2008) A functional interaction between RIP140 and PGC-1 regulates the expression of the lipid droplet protein CIDEA. Molecular and Cellular Biology, 28 (22). pp. 6785-6795. doi:10.1128/MCB.00504-08