2021

Keeling, Matt J., Hill, Edward M., Gorsich, Erin E., Penman, Bridget S., Guyver-Fletcher, Glen, Holmes, Alexander, Leng, Trystan, McKimm, Hector, Tamborrino, Massimiliano, Dyson, Louise and Tildesley, Michael J. (2021) Predictions of COVID-19 dynamics in the UK : short-term forecasting and analysis of potential exit strategies. PLoS Computational Biology, 17 (1). e1008619. doi:10.1371/journal.pcbi.1008619

2020

(2020) Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020. Eurosurveillance, 25 (42). 2000685. doi:10.2807/1560-7917.es.2020.25.42.2000685

Penman, Bridget S. and Gandon, Sylvain (2020) Adaptive immunity selects against malaria infection blocking mutations. PLOS Computational Biology, 16 (10). e1008181. doi:10.1371/journal.pcbi.1008181

White, Connor, Pellis, Lorenzo, Keeling, Matthew James and Penman, Bridget S. (2020) Detecting HLA-infectious disease associations for multi-strain pathogens. Infection, Genetics and Evolution, 83 . 104344. doi:10.1016/j.meegid.2020.104344

(2020) Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans. Scientific Reports, 10 (1). 3248. doi:10.1038/s41598-020-58897-5

Keeling, Matt J., Tildesley, Michael J., Atkins, Benjamin D., Penman, Bridget S., Southall, Emma, Guyver-Fletcher, Glen, Holmes, Alexander, McKimm, Hector, Gorsich, Erin E., Hill, Edward M. and Dyson, Louise (2020) The impact of school reopening on the spread of COVID-19 in England. Philosophical Transactions of the Royal Society B: Biological Sciences . (In Press)

2019

Hockham, Carinna, Ekwattanakit, Supachai, Bhatt, Samir, Penman, Bridget S., Gupta, Sunetra, Viprakasit, Vip and Piel, Frédéric B (2019) Estimating the burden of α-thalassaemia in Thailand using a comprehensive prevalence database for Southeast Asia. eLife, 8 . e40580. doi:10.7554/eLife.40580

Spensley, Katrina J., Wikramaratna, Paul S., Penman, Bridget S., Walker, Andrew, Smith, Adrian L., Pybus, Oliver G., Jean, Létitia , Gupta, Sunetra and Lourenço, José (2019) Reverse immunodynamics : a new method for identifying targets of protective immunity. Scientific Reports, 9 . 2164 . doi:10.1038/s41598-018-37288-x

2018

Hockham , C., Bhatt, S., Colah, R., Mukherjee, M. B., Penman, Bridget S., Gupta, S. and Piel, F. B. (2018) The spatial epidemiology of sickle-cell anaemia in India. Scientific Reports, 8 . 17685. doi:10.1038/s41598-018-36077-w

Penman, Bridget S. and Gupta, Sunetra (2018) Detecting signatures of past pathogen selection on human HLA loci : are there needles in the haystack? Parasitology , 145 (6). pp. 731-739. doi:10.1017/S0031182017001159

2017

Tusco, Radu, Jacomin, Anne-Claire, Jain, Ashish, Penman, Bridget S., Bowitz Larsen, Kenneth, Johansen, Terje and Nezis, Ioannis P. (2017) Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses. Nature Communications, 8 . 1264 . doi:10.1038/s41467-017-01287-9

Penman, Bridget S., Gupta, S. and Shanks, G. D. (2017) Rapid mortality transition of Pacific Islands in the 19th century. Epidemiology and Infection, 145 (1). pp. 1-11. doi:10.1017/S0950268816001989

2016

Penman, Bridget S., Moffett, Ashley, Chazara, Olympe, Gupta, Sunetra and Parham, Peter (2016) Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution. Immunogenetics, 68 (10). pp. 755-764. doi:10.1007/s00251-016-0935-9

Gonçalves, Bronner P., Gupta, Sunetra and Penman, Bridget S. (2016) Sickle haemoglobin, haemoglobin C and malaria mortality feedbacks. Malaria Journal, 15 (1). pp. 1-7. 26. doi:10.1186/s12936-015-1077-5

2015

Hockham, Carinna, Piel, Frédéric B., Gupta, Sunetra and Penman, Bridget S. (2015) Understanding the contrasting spatial haplotype patterns of malaria-protective β-globin polymorphisms. Infection, Genetics and Evolution , 36 . pp. 174-183. doi:10.1016/j.meegid.2015.09.018

Levin, Bruce R., Watkins, Eleanor R., Penman, Bridget S., Lourenço, José, Buckee, Caroline O., Maiden, Martin C. J. and Gupta, Sunetra (2015) Vaccination drives changes in metabolic and virulence profiles of Streptococcus pneumoniae. PLoS Pathogens, 11 (7). e1005034. doi:10.1371/journal.ppat.1005034

Penman, Bridget S., Gupta, Sunetra and Weatherall, David J. (2015) Epistasis and the sensitivity of phenotypic screens for beta thalassaemia. British Journal of Haematology, 169 (1). pp. 117-128. doi:10.1111/bjh.13241

2013

Penman, Bridget S., Ashby, B., Buckee, C. O. and Gupta, S. (2013) Pathogen selection drives nonoverlapping associations between HLA loci. Proceedings of the National Academy of Sciences of the United States of America, 110 (48). pp. 19645-19650. doi:10.1073/pnas.1304218110

2012

Penman, Bridget S., Gupta, Sunetra and Buckee, Caroline O. (2012) The emergence and maintenance of sickle cell hotspots in the Mediterranean. Infection, Genetics and Evolution , 12 (7). pp. 1543-1550. doi:10.1016/j.meegid.2012.06.001

2010

Penman, Bridget S., Buckee, Caroline, Gupta, Sunetra and Nee, Sean (2010) Genome-wide association studies in Plasmodium species. BMC Biology, 8 (1). p. 90. doi:10.1186/1741-7007-8-90

2009

Penman, Bridget S., Pybus, Oliver G., Weatherall, David J. and Gupta, Sunetra (2009) Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean. Proceedings of the National Academy of Sciences of the United States of America, 106 (50). pp. 21242-21246. doi:10.1073/pnas.0910840106

2008

Penman, Bridget S. and Gupta, Sunetra (2008) Evolution of virulence in malaria. Journal of Biology, 7 (6). 22. doi:10.1186/jbiol83

Buckee, C. O., Jolley, K. A., Recker, M., Penman, Bridget S., Kriz, P., Gupta, S. and Maiden, M. C. J. (2008) Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis. Proceedings of the National Academy of Sciences of the United States of America, 105 (39). pp. 15082-15087. doi:10.1073/pnas.0712019105

2005

Williams, Thomas N., Mwangi, Tabitha W., Wambua, Sammy, Peto, Timothy E. A., Weatherall, David J., Gupta, Sunetra, Recker, Mario, Penman, Bridget S., Uyoga, Sophie, Macharia, Alex, Mwacharo, Jedidah K., Snow, Robert W. and Marsh, Kevin. (2005) Negative epistasis between the malaria-protective effects of α+-thalassemia and the sickle cell trait. Nature Genetics, 37 (11). pp. 1253-1257. doi:10.1038/ng1660