2022

Introini, Viola, Marin-Menendez, Alejandro, Nettesheim, Guilherme, Lin, Yen-Chun, Kariuki, Silvia N., Smith, Adrian L., Jean, Letitia, Brewin, John N., Rees, David C., Cicuta, Pietro, Rayner, Julian C. and Penman, Bridget S. (2022) The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion. Scientific Reports, 12 (1). 8934. doi:10.1038/s41598-022-12060-4 ISSN 2045-2322.

2021

Keeling, Matt J., Tildesley, Michael J., Atkins, Benjamin D., Penman, Bridget S., Southall, Emma, Guyver-Fletcher, Glen, Holmes, Alexander, McKimm, Hector, Gorsich, Erin E., Hill, Edward M. and Dyson, Louise (2021) The impact of school reopening on the spread of COVID-19 in England. Philosophical Transactions of the Royal Society B: Biological Sciences, 376 (1829). 20200261. doi:10.1098/rstb.2020.0261 ISSN 0962-8436.

Keeling, Matt J., Hill, Edward M., Gorsich, Erin E., Penman, Bridget S., Guyver-Fletcher, Glen, Holmes, Alexander, Leng, Trystan, McKimm, Hector, Tamborrino, Massimiliano, Dyson, Louise and Tildesley, Michael J. (2021) Predictions of COVID-19 dynamics in the UK : short-term forecasting and analysis of potential exit strategies. PLoS Computational Biology, 17 (1). e1008619. doi:10.1371/journal.pcbi.1008619 ISSN 1553-7358.

2020

(2020) Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020. Eurosurveillance, 25 (42). 2000685. doi:10.2807/1560-7917.es.2020.25.42.2000685 ISSN 1560-7917.

Penman, Bridget S. and Gandon, Sylvain (2020) Adaptive immunity selects against malaria infection blocking mutations. PLOS Computational Biology, 16 (10). e1008181. doi:10.1371/journal.pcbi.1008181 ISSN 1553-7358.

White, Connor, Pellis, Lorenzo, Keeling, Matthew James and Penman, Bridget S. (2020) Detecting HLA-infectious disease associations for multi-strain pathogens. Infection, Genetics and Evolution, 83 . 104344. doi:10.1016/j.meegid.2020.104344 ISSN 1567-1348.

(2020) Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans. Scientific Reports, 10 (1). 3248. doi:10.1038/s41598-020-58897-5 ISSN 2045-2322.

2019

Hockham, Carinna, Ekwattanakit, Supachai, Bhatt, Samir, Penman, Bridget S., Gupta, Sunetra, Viprakasit, Vip and Piel, Frédéric B (2019) Estimating the burden of α-thalassaemia in Thailand using a comprehensive prevalence database for Southeast Asia. eLife, 8 . e40580. doi:10.7554/eLife.40580 ISSN 2050-084X.

Spensley, Katrina J., Wikramaratna, Paul S., Penman, Bridget S., Walker, Andrew, Smith, Adrian L., Pybus, Oliver G., Jean, Létitia , Gupta, Sunetra and Lourenço, José (2019) Reverse immunodynamics : a new method for identifying targets of protective immunity. Scientific Reports, 9 . 2164 . doi:10.1038/s41598-018-37288-x ISSN 2045-2322.

2018

Hockham , C., Bhatt, S., Colah, R., Mukherjee, M. B., Penman, Bridget S., Gupta, S. and Piel, F. B. (2018) The spatial epidemiology of sickle-cell anaemia in India. Scientific Reports, 8 . 17685. doi:10.1038/s41598-018-36077-w ISSN 2045-2322.

Penman, Bridget S. and Gupta, Sunetra (2018) Detecting signatures of past pathogen selection on human HLA loci : are there needles in the haystack? Parasitology , 145 (6). pp. 731-739. doi:10.1017/S0031182017001159 ISSN 0031-1820.

2017

Tusco, Radu, Jacomin, Anne-Claire, Jain, Ashish, Penman, Bridget S., Bowitz Larsen, Kenneth, Johansen, Terje and Nezis, Ioannis P. (2017) Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses. Nature Communications, 8 . 1264 . doi:10.1038/s41467-017-01287-9 ISSN 2041-1723.

Penman, Bridget S., Gupta, S. and Shanks, G. D. (2017) Rapid mortality transition of Pacific Islands in the 19th century. Epidemiology and Infection, 145 (1). pp. 1-11. doi:10.1017/S0950268816001989 ISSN 0950-2688.

2016

Penman, Bridget S., Moffett, Ashley, Chazara, Olympe, Gupta, Sunetra and Parham, Peter (2016) Reproduction, infection and killer-cell immunoglobulin-like receptor haplotype evolution. Immunogenetics, 68 (10). pp. 755-764. doi:10.1007/s00251-016-0935-9 ISSN 0093-7711.

Gonçalves, Bronner P., Gupta, Sunetra and Penman, Bridget S. (2016) Sickle haemoglobin, haemoglobin C and malaria mortality feedbacks. Malaria Journal, 15 (1). pp. 1-7. 26. doi:10.1186/s12936-015-1077-5 ISSN 1475-2875.

2015

Hockham, Carinna, Piel, Frédéric B., Gupta, Sunetra and Penman, Bridget S. (2015) Understanding the contrasting spatial haplotype patterns of malaria-protective β-globin polymorphisms. Infection, Genetics and Evolution , 36 . pp. 174-183. doi:10.1016/j.meegid.2015.09.018 ISSN 1567-1348.

Levin, Bruce R., Watkins, Eleanor R., Penman, Bridget S., Lourenço, José, Buckee, Caroline O., Maiden, Martin C. J. and Gupta, Sunetra (2015) Vaccination drives changes in metabolic and virulence profiles of Streptococcus pneumoniae. PLoS Pathogens, 11 (7). e1005034. doi:10.1371/journal.ppat.1005034 ISSN 1553-7374.

Penman, Bridget S., Gupta, Sunetra and Weatherall, David J. (2015) Epistasis and the sensitivity of phenotypic screens for beta thalassaemia. British Journal of Haematology, 169 (1). pp. 117-128. doi:10.1111/bjh.13241 ISSN 0007-1048.

2013

Penman, Bridget S., Ashby, B., Buckee, C. O. and Gupta, S. (2013) Pathogen selection drives nonoverlapping associations between HLA loci. Proceedings of the National Academy of Sciences of the United States of America, 110 (48). pp. 19645-19650. doi:10.1073/pnas.1304218110 ISSN 0027-8424.

2012

Penman, Bridget S., Gupta, Sunetra and Buckee, Caroline O. (2012) The emergence and maintenance of sickle cell hotspots in the Mediterranean. Infection, Genetics and Evolution , 12 (7). pp. 1543-1550. doi:10.1016/j.meegid.2012.06.001 ISSN 1567-1348.

2010

Penman, Bridget S., Buckee, Caroline, Gupta, Sunetra and Nee, Sean (2010) Genome-wide association studies in Plasmodium species. BMC Biology, 8 (1). p. 90. doi:10.1186/1741-7007-8-90 ISSN 1741-7007.

2009

Penman, Bridget S., Pybus, Oliver G., Weatherall, David J. and Gupta, Sunetra (2009) Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean. Proceedings of the National Academy of Sciences of the United States of America, 106 (50). pp. 21242-21246. doi:10.1073/pnas.0910840106 ISSN 0027-8424.

2008

Penman, Bridget S. and Gupta, Sunetra (2008) Evolution of virulence in malaria. Journal of Biology, 7 (6). 22. doi:10.1186/jbiol83 ISSN 1475-4924.

Buckee, C. O., Jolley, K. A., Recker, M., Penman, Bridget S., Kriz, P., Gupta, S. and Maiden, M. C. J. (2008) Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis. Proceedings of the National Academy of Sciences of the United States of America, 105 (39). pp. 15082-15087. doi:10.1073/pnas.0712019105 ISSN 0027-8424.

2005

Williams, Thomas N., Mwangi, Tabitha W., Wambua, Sammy, Peto, Timothy E. A., Weatherall, David J., Gupta, Sunetra, Recker, Mario, Penman, Bridget S., Uyoga, Sophie, Macharia, Alex, Mwacharo, Jedidah K., Snow, Robert W. and Marsh, Kevin. (2005) Negative epistasis between the malaria-protective effects of α+-thalassemia and the sickle cell trait. Nature Genetics, 37 (11). pp. 1253-1257. doi:10.1038/ng1660 ISSN 1061-4036.