2022

Menon, Navya, Richmond, Daniel, Rahman, Mohammad Rejaur and Menon, Binuraj R. K. (2022) Versatile and facile one-pot biosynthesis for amides and carboxylic acids in E. coli by engineering auxin pathways of plant microbiomes. ACS Catalysis, 12 (4). pp. 2309-2319. doi:10.1021/acscatal.1c04901 ISSN 2155-5435.

Menon, Binuraj R. K., Richmond, Daniel and Menon, Navya (2022) Halogenases for biosynthetic pathway engineering : toward new routes to naturals and non-naturals. Catalysis Reviews: Science and Engineering, 64 (3). pp. 533-591. doi:10.1080/01614940.2020.1823788 ISSN 0161-4940.

2021

Menon, Binuraj R. K. (2021) The missing colours of chemistry. Nature Chemistry, 13 . pp. 101-106. doi:10.1038/s41557-020-00632-8

2019

Cummings, Matthew, Peters, Anna D. , Whitehead, George F. S. , Menon, Binuraj R. K., Micklefield, Jason and Webb, Simon J. (2019) Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli. PLoS Biology, 17 (7). e3000347. doi:10.1371/journal.pbio ISSN 1545-7885.

2018

Bennett, Matthew R., Thompson, Mark L., Shepherd, Sarah A., Dunstan, Mark S., Herbert, Abigail J., Smith, Duncan R. M., Cronin, Victoria A., Menon, Binuraj R. K., Levy, Colin and Micklefield, Jason (2018) Structure and biocatalytic scope of coclaurine N-methyltransferase. Angewandte Chemie International Edition, 57 (33). pp. 10600-10604. doi:10.1002/anie.201805060 ISSN 1433-7851.

Menon, Binuraj R. K. and Jenner, Matthew (2018) Biosynthesis : reprogramming assembly lines. Nature Chemistry, 10 (3). pp. 245-247. doi:10.1038/nchem.2941 ISSN 1755-4330.

2017

Menon, Binuraj R. K., Brandenburger, Eileen, Sharif, Humera H., Klemstein, Ulrike, Shepherd, Sarah A., Greaney, Michael F. and Micklefield, Jason (2017) RadH : a versatile halogenase for integration into synthetic pathways. Angewandte Chemie International Edition, 56 (39). pp. 11841-11845. doi:10.1002/anie.201706342 ISSN 1433-7851.

Latham, Jonathan, Brandenburger, Eileen, Shepherd, Sarah A., Menon, Binuraj R. K. and Micklefield, Jason (2017) Development of halogenase enzymes for use in synthesis. Chemical Reviews . doi:10.1021/acs.chemrev.7b00032 ISSN 0009-2665.

2016

Ortmayer, Mary, Lafite, Pierre, Menon, Binuraj R. K., Tralau, Tewes, Fisher, Karl, Denkhaus, Lukas, Scrutton, Nigel S., Rigby, Stephen E. J., Munro, Andrew W., Hay, Sam and Leys, David (2016) An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme. Nature, 539 (7630). pp. 593-597. doi:10.1038/nature20159 ISSN 0028-0836.

Menon, Binuraj R. K., Latham, Jonathan, Dunstan, Mark S., Brandenburger, Eileen, Klemstein, Ulrike, Leys, David, Karthikeyan, Chinnan, Greaney, Michael F., Shepherd, Sarah A. and Micklefield, Jason (2016) Structure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymes. Organic and Biomolecular Chemistry, 14 (39). pp. 9354-9361. doi:10.1039/C6OB01861K ISSN 1477-0520.

Menon, Binuraj R. K., Hardman, Samantha J. O., Scrutton, Nigel S. and Heyes, Derren J. (2016) Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR). Journal of Photochemistry and Photobiology B: Biology , 161 . pp. 236-243. doi:10.1016/j.jphotobiol.2016.05.029 ISSN 1011-1344.

Latham, Jonathan, Henry, Jean-Marc, Sharif, Humera H., Menon, Binuraj R. K., Shepherd, Sarah A., Greaney, Michael F. and Micklefield, Jason (2016) Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation. Nature Communications, 7 . 11873. doi:10.1038/ncomms11873 ISSN 2041-1723.

Shepherd, Sarah A., Menon, Binuraj R. K., Fisk, Heidi, Struck, Anna-Winona, Levy, Colin, Leys, David and Micklefield, Jason (2016) A structure-guided switch in the regioselectivity of a tryptophan halogenase. Chembiochem, 17 (9). pp. 821-824. doi:10.1002/cbic.201600051 ISSN 1439-4227.

2015

Menon, Navya, Pásztor, András, Menon, Binuraj R. K., Kallio, Pauli, Fisher, Karl, Akhtar, M. Kalim, Leys, David, Jones, Patrik R. and Scrutton, Nigel S. (2015) A microbial platform for renewable propane synthesis based on a fermentative butanol pathway. Biotechnology for Biofuels, 8 (1). 61. doi:10.1186/s13068-015-0231-1 ISSN 1754-6834.

Menon, Binuraj R. K., Menon, Navya, Fisher, Karl, Rigby, Stephen E. J., Leys, David and Scrutton, Nigel S. (2015) Glutamate 338 is an electrostatic facilitator of C-Co bond breakage in a dynamic/electrostatic model of catalysis by ornithine aminomutase. FEBS Journal, 282 (7). pp. 1242-1255. doi:10.1111/febs.13215 ISSN 1742-464x.

Shepherd, Sarah A., Karthikeyan, Chinnan, Latham, Jonathan, Struck, Anna-Winona, Thompson, Mark L., Menon, Binuraj R. K., Styles, Matthew Q., Levy, Colin, Leys, David and Micklefield, Jason (2015) Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes. Chemical Science, 6 (6). pp. 3454-3460. doi:10.1039/C5SC00913H ISSN 2041-6520.

2014

Menon, Binuraj R. K., Fisher, Karl, Rigby, Stephen E. J., Scrutton, Nigel S. and Leys, David (2014) A conformational sampling model for radical catalysis in pyridoxal phosphate- and cobalamin-dependent enzymes. Journal of Biological Chemistry, 289 (49). pp. 34161-34174. doi:10.1074/jbc.M114.590471 ISSN 0021-9258.

2009

Menon, Binuraj R. K., Waltho, Jonathan P., Scrutton, Nigel S. and Heyes, Derren J. (2009) Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase. Journal of Biological Chemistry, 284 (27). pp. 18160-18166. doi:10.1074/jbc.M109.020719 ISSN 0021-9258.

Menon, Binuraj R. K., Davison, Paul A., Hunter, C. Neil, Scrutton, Nigel S. and Heyes, Derren J. (2009) Mutagenesis alters the catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase. Journal of Biological Chemistry, 285 (3). pp. 2113-2119. doi:10.1074/jbc.M109.071522 ISSN 0021-9258.

2008

Heyes, Derren J., Menon, Binuraj R. K. , Sakuma, Michiyo and Scrutton, Nigel S. (2008) Conformational events during ternary enzyme−substrate complex formation are rate limiting in the catalytic cycle of the light-driven enzyme protochlorophyllide oxidoreductase. Biochemistry, 47 (41). pp. 10991-10998. doi:10.1021/bi801521c ISSN 0006-2960.