Journal Article

Hadjicharalambous, Andreas, Bournakas, Nikolaos, Newman, Hector, Skynner, Michael J. and Beswick, Paul (2022) Antimicrobial and cell-penetrating peptides : understanding penetration for the design of novel conjugate antibiotics. Antibiotics, 11 (11). 1636. doi:10.3390/antibiotics11111636 ISSN 2079-6382.

Graham, Chris L. B., Newman, Hector, Gillett, Francesca, Smart, Katie, Briggs, Nicholas, Banzhaf, Manuel and Roper, David I. (2021) A dynamic network of proteins facilitate cell envelope biogenesis in gram-negative bacteria. International Journal of Molecular Sciences, 22 (23). e12831. doi:10.3390/ijms222312831 ISSN 1422-0067.

Newman, Hector, Krajnc, Alen, Bellini, Dom, Eyermann, Charles J., Boyle, Grant A., Paterson, Neil G., McAuley, Katherine E., Lesniak, Robert, Gangar, Mukesh, von Delft, Frank, Brem, Jürgen, Chibale, Kelly, Schofield, Christopher J. and Dowson, Christopher G. (2021) High-throughput crystallography reveals boron-containing inhibitors of a Penicillin-binding protein with di- and tricovalent binding modes. Journal of Medicinal Chemistry, 64 (15). pp. 11379-11394. doi:10.1021/acs.jmedchem.1c00717 ISSN 0022-2623.

(2020) Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion. Chemical Science, 11 (39). pp. 10792-10801. doi:10.1039/D0SC01232G ISSN 2041-6520.

Bellini, Dom, Koekemoer, Lizbé, Newman, Hector and Dowson, Christopher G. (2019) Novel and improved crystal structures of H. influenzae, E. coli and P. aeruginosa penicillin-binding protein 3 (PBP3) and N. gonorrhoeae PBP2 : toward a better understanding of β-Lactam target-mediated resistance. Journal of Molecular Biology, 431 (18). pp. 3501-3519. doi:10.1016/j.jmb.2019.07.010 ISSN 0022-2836.

Thesis

Newman, Hector (2021) Biophysical and biochemical studies of penicillin binding proteins and novel PBP3 inhibitors. PhD thesis, University of Warwick.