Journal Article

Billington, Karen, Halliday, Clare, Madden, Ross, Dyer, Philip, Barker, Amy, Moreira-Leite, Flavia, Carrington, Mark, Vaughan, Sue, Hertz-Fowler, Christiane, Dean, Samuel, Sunter, Jack, Wheeler, Richard and Gull, Keith (2023) Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei. Nature microbiology, 8 . pp. 533-547. doi:10.1038/s41564-022-01295-6 ISSN 2058-5276.

Bick, D., Bishop, J. R., Coleman, T., Dean, S., Edwards, E., Frawley, H., Gkini, E., Hay-Smith, J., Hemming, K., Jones, E., Oborn, E., Pearson, M., Salmon, V., Webb, S. and MacArthur, C. (2022) Antenatal preventative pelvic floor muscle exercise intervention led by midwives to reduce postnatal urinary incontinence (APPEAL) : protocol for a feasibility and pilot cluster randomised controlled trial. Pilot and Feasibility Studies, 8 (1). 231. doi:10.1186/s40814-022-01185-y ISSN 2055-5784.

Jeilani, Milad, Billington, Karen, Sunter, Jack Daniel, Dean, Samuel and Wheeler, Richard John (2022) Nucleolar targeting in an early-branching eukaryote suggests a general mechanism for ribosome protein sorting. Journal of Cell Science, 135 (19). jcs259701. doi:10.1242/jcs.259701 ISSN 0021-9533.

López-Escobar, Lara, Hänisch, Benjamin, Halliday, Clare, Ishii, Midori, Akiyoshi, Bungo, Dean, Samuel, Sunter, Jack Daniel, Wheeler, Richard John and Gull, Keith (2022) Stage-specific transcription activator ESB1 regulates monoallelic antigen expression in Trypanosoma brucei. Nature Microbiology, 7 (8). pp. 1280-1290. doi:10.1038/s41564-022-01175-z ISSN 2058-5276.

Dean, Samuel (2022) Preprint Highlight : FLAgellum member 8 modulates extravascular trypanosome distribution in the mammalian host. Molecular Biology of the Cell, 33 . 5. doi:10.1091/mbc.p22-02-1006 ISSN 1939-4586.

Vélez-Ramírez, Daniel E., Shimogawa, Michelle M., Ray, Sunayan S., Lopez, Andrew, Rayatpisheh, Shima, Langousis, Gerasimos, Gallagher-Jones, Marcus, Dean, Samuel, Wohlschlegel, James A., Hill, Kent L. and Phillips, Margaret (2021) APEX2 proximity proteomics resolves flagellum subdomains and identifies flagellum tip-specific proteins in Trypanosoma brucei. mSphere, 6 (1). e01090-20. doi:10.1128/mSphere.01090-20 ISSN 2379-5042.

Dean, Samuel (2021) Basic biology of Trypanosoma brucei with reference to the development of chemotherapies. Current Pharmaceutical Design, 27 (14). pp. 1650-1670. doi:10.2174/1381612827666210119105008 ISSN 1873-4286.

Atkins, Madison, Týč, Jiří, Shafiq, Shahaan, Ahmed, Manu, Bertiaux, Eloïse, De Castro Neto, Artur Leonel, Sunter, Jack, Bastin, Philippe, Dean, Samuel and Vaughan, Sue (2020) CEP164C regulates flagellum length in stable flagella. Journal of Cell Biology, 220 (1). e202001160. doi:10.1083/jcb.202001160 ISSN 0021-9525.

Dean, Samuel, Moreira-Leite, Flavia and Gull, Keith (2019) Basalin is an evolutionarily unconstrained protein revealed via a conserved role in flagellum basal plate function. eLife, 8 . e42282. doi:10.7554/eLife.42282.001 ISSN 2050-084X.

Halliday, Clare, Billington, Karen, Wang, Ziyin, Madden, Ross, Dean, Samuel, Sunter, Jack Daniel and Wheeler, Richard John (2019) Cellular landmarks of Trypanosoma brucei and Leishmania mexicana. Molecular and Biochemical Parasitology, 230 . pp. 24-36. doi:10.1016/j.molbiopara.2018.12.003 ISSN 0166-6851.

Buscaglia, Carlos A., Costa, Fernanda Cristina, Francisco, Amanda Fortes, Jayawardhana, Shiromani, Calderano, Simone Guedes, Lewis, Michael D., Olmo, Francisco, Beneke, Tom, Gluenz, Eva, Sunter, Jack, Dean, Samuel, Kelly, John Morrison and Taylor, Martin Craig (2018) Expanding the toolbox for Trypanosoma cruzi : a parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping. PLoS Neglected Tropical Diseases, 12 (4). e0006388. doi:10.1371/journal.pntd.0006388 ISSN 1935-2727.

(2017) Genome sequencing reveals metabolic and cellular interdependence in an amoeba-kinetoplastid symbiosis. Scientific Reports, 7 (1). doi:10.1038/s41598-017-11866-x ISSN 2045-2322.

Dean, Samuel, Sunter, Jack D. and Wheeler, Richard J. (2017) TrypTag.org : a Trypanosome genome-wide protein localisation resource. Trends in Parasitology, 33 (2). pp. 80-82. doi:10.1016/j.pt.2016.10.009 ISSN 1471-4922.

Dyer, Philip, Dean, Samuel and Sunter, Jack (2016) High-throughput Gene Tagging in Trypanosoma brucei. Journal of Visualized Experiments (114). doi:10.3791/54342 ISSN 1940-087X.

Dean, Samuel, Moreira-Leite, Flavia, Varga, Vladimir and Gull, Keith (2016) Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes. Proceedings of the National Academy of Sciences of the United States of America, 113 (35). E5135-E5143. doi:10.1073/pnas.1604258113 ISSN 0027-8424.

Sunter, J. D., Varga, V., Dean, S. and Gull, K. (2015) A dynamic coordination of flagellum and cytoplasmic cytoskeleton assembly specifies cell morphogenesis in trypanosomes. Journal of Cell Science, 128 (8). pp. 1580-1594. doi:10.1242/jcs.166447 ISSN 0021-9533.

Dean, Samuel, Sunter, Jack, Wheeler, Richard J., Hodkinson, Ian, Gluenz, Eva and Gull, Keith (2015) A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids. Open Biology, 5 (1). 140197. doi:10.1098/rsob.140197 ISSN 2046-2441.

Book Item

Dean, Samuel and Sunter, Jack (2020) Light microscopy in trypanosomes : use of fluorescent proteins and tags. In: Michels, P. and Ginger, M. and Zilberstein, D., (eds.) Trypanosomatids. Methods in Molecular Biology, 2116 . New York, NY.: Humana Press, pp. 367-383. ISBN 9781071602935

Working or Discussion Paper

Atkins, Madison, Týč, Jiří, Shafiq, Shahaan, Ahmed, Manu, Bertiaux, Eloïse, De Castro Neto, Artur Leonel, Sunter, Jack, Bastin, Philippe, Dean, Samuel and Vaughan, Sue (2019) A key regulatory protein for flagellum length control in stable flagella. Working Paper. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory. (Unpublished)

Journal Item

Sáez Conde, Julia and Dean, Samuel (2022) Structure, function and druggability of the African trypanosome flagellum. Journal of Cellular Physiology, 237 (6). pp. 2654-2667. doi:10.1002/jcp.30778