Journal Article

Alhujaily, Muhanad Musaad M., Abbas, Hafsa, Xue, Mingzhan, de la Fuente, Alberto, Rabbani, Naila and Thornalley, Paul J. (2021) Studies of glyoxalase 1-linked multidrug resistance reveal glycolysis-derived reactive metabolite, methylglyoxal, is a common contributor in cancer chemotherapy targeting the spliceosome. Frontiers in Oncology, 11 . 748698. doi:10.3389/fonc.2021.748698

Irshad, Zehra, Xue, Mingzhan, Ashour, Amal, Larkin, James R., Thornalley, Paul J. and Rabbani, Naila (2019) Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal. Scientific Reports, 9 (1). doi:10.1038/s41598-019-44358-1

Fourdinier, Ophélie, Schepers, Eva, Metzinger-Le Meuth, Valérie, Glorieux, Griet, Liabeuf, Sophie, Verbeke, Francis, Vanholder, Raymond, Brigant, Benjamin, Pletinck, Anneleen, Diouf, Momar, Burtey, Stéphane, Choukroun, Gabriel, Massy, Ziad A., Metzinger, Laurent and Thornalley, Paul J. (2019) Serum levels of miR-126 and miR-223 and outcomes in chronic kidney disease patients. Scientific Reports, 9 (1). doi:10.1038/s41598-019-41101-8

Rabbani, Naila and Thornalley, Paul J. (2019) Glyoxalase 1 modulation in obesity and diabetes. Antioxidants & Redox Signaling, 30 (3). pp. 354-374. doi:10.1089/ars.2017.7424

(2018) Correction to: Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease. Proteome Science, 16 (1). doi:10.1186/s12953-018-0142-8

Legrand, Catherine, Ahmed, Usman, Anwar, Attia, Rajpoot, Kashif, Pasha, Sabah, Lambert, Cécile, Davidson, Rose K., Clark , Ian M., Thornalley, Paul J., Henrotin, Yves and Rabbani, Naila (2018) Glycation marker glucosepane increases with the progression of osteoarthritis and correlates with morphological and functional changes of cartilage in vivo. Arthritis Research & Therapy, 20 . 131. doi:10.1186/s13075-018-1636-6

Chiu, Chung-Jung, Rabbani, Naila, Rowan, Sheldon, Chang, Min-Lee, Sawyer, Sherilyn, Hu, Frank B., Willett, Walter, Thornalley, Paul J., Anwar, Attia, Bar, Liliana, Kang, Jae H. and Taylor, Allen (2018) Studies of advanced glycation end products and oxidation biomarkers for type 2 diabetes. BioFactors, 44 (3). pp. 281-288. doi:10.1002/biof.1423

Rabbani, Naila and Thornalley, Paul J. (2018) Advanced glycation end products in the pathogenesis of chronic kidney disease. Kidney International, 93 (4). pp. 803-813. doi:10.1016/j.kint.2017.11.034

Rabbani, Naila and Thornalley, Paul J. (2018) Advanced glycation endproducts in the pathogenesis of chronic kidney disease. Kidney International, 93 (4). pp. 803-813. doi:10.1016/j.kint.2017.11.034

Rabbani, Naila, Xue, Mingzhan, Weickert, Martin O. and Thornalley, Paul J. (2018) Multiple roles of glyoxalase 1-mediated suppression of methylglyoxal glycation in cancer biology—involvement in tumour suppression, tumour growth, multidrug resistance and target for chemotherapy. Seminars in Cancer Biology, 49 . pp. 83-93. doi:10.1016/j.semcancer.2017.05.006

Anwar, Attia, Abruzzo, Provvidenza Maria, Pasha, Sabah, Rajpoot, Kashif, Bolotta, Alessandra, Ghezzo, Alessandro, Marini, Marina, Posar, Annio, Visconti, Paola, Thornalley, Paul J. and Rabbani, Naila (2018) Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism - a source of biomarkers for clinical diagnosis. Molecular Autism, 9 . p. 3. doi:10.1186/s13229-017-0183-3

(2018) Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease. Proteome Science, 16 (1). 4. doi:10.1186/s12953-018-0131-y

Xue, Mingzhan, Shafie, Alaa, Qaiser, Talha, Rajpoot, Nasir M., Kaltsas, Gregory, Gopalakrishnan, Kishore, Fisk, Adrian, Dimitriadis, Georgios K., Grammatopoulos, Dimitris, Rabbani, Naila, Thornalley, Paul J., Weickert, Martin O. and James, Sean G. (2017) Glyoxalase 1 copy number variation in patients with well differentiated gastroentero-pancreatic neuroendocrine tumours (GEP-NET). Oncotarget, 8 . pp. 76961-76973. doi:10.18632/oncotarget.20290

Razny, Urszula, Goralska, Joanna, Zdzienicka, Anna, Fedak, Danuta, Masania, Jinit , Rabbani, Naila, Thornalley, Paul J., Pawlica-Gosiewska, Dorota, Gawlik, Katarzyna, Dembinska-Kiec, Aldona, Solnica, Bogdan and Malczewska-Malec, Malgorzata (2017) Relation of the protein glycation, oxidation and nitration to the osteocalcin level in obese subjects. Acta Biochimica Polonica, 64 (3). pp. 415-422. doi:10.18388/abp.2017_1627

Stratmann, Bernd, Goldstein, Bernhard, Thornalley, Paul J., Rabbani, Naila and Tschoepe, Diethelm (2017) Intracellular accumulation of methylglyoxal by glyoxalase 1 knock down alters collagen homoeostasis in L6 myoblasts. International Journal of Molecular Sciences, 18 (3). 480. doi:10.3390/ijms18030480

Stratmann, Bernd, Engelbrecht, Britta, Espelage, Britta C., Klusmeier, Nadine, Tiemann, Janina, Gawlowski, Thomas, Mattern, Yvonne, Eisenacher, Martin, Meyer, Helmut E., Rabbani, Naila, Thornalley, Paul J., Tschoepe, Diethelm, Poschmann, Gereon and Stühler, Kai (2016) Glyoxalase 1-knockdown in human aortic endothelial cells – effect on the proteome and endothelial function estimates. Scientific Reports, 6 . 37737. doi:10.1038/srep37737

Shafie, Alaa, Xue, Mingzhan, Barker, Guy C., Zehnder, Daniel, Thornalley, Paul J. and Rabbani, Naila (2016) Reappraisal of putative glyoxalase 1-deficient mouse and dicarbonyl stress on embryonic stem cells in vitro. Biochemical Journal, 473 (22). pp. 4255-4270. doi:10.1042/BCJ20160691

Anwar, Attia, Marini, Marina, Abruzzo, Provvidenza Maria, Bolotta, Alessandra, Ghezzo, Alessandro, Visconti, Paola, Thornalley, Paul J. and Rabbani, Naila (2016) Quantitation of plasma thiamine, related metabolites and plasma protein oxidative damage markers in children with autism spectrum disorder and healthy controls. Free Radical Research, 50 (Supplement 1). S85-S90 . doi:10.1080/10715762.2016.1239821

Ahmed, Usman, Anwar, Attia, Savage, Richard S., Thornalley, Paul J. and Rabbani, Naila (2016) Protein oxidation, nitration and glycation biomarkers for early-stage diagnosis of osteoarthritis of the knee and typing and progression of arthritic disease. Arthritis Research & Therapy, 18 (1). 250. doi:10.1186/s13075-016-1154-3

Rabbani, Naila, Xue, Mingzhan and Thornalley, Paul J. (2016) Methylglyoxal-induced dicarbonyl stress in aging and disease : first steps towards glyoxalase 1-based treatments. Clinical Science, 130 (19). pp. 1677-1696. doi:10.1042/CS20160025

Masania, Jinit , Malczewska-Malec, Malgorzata, Razny, Urszula, Goralska, Joanna, Zdzienicka, Anna, Kiec-Wilk, Beata, Gruca, Anna, Stancel-Mozwillo, Julita, Dembinska-Kiec, Aldona, Rabbani, Naila and Thornalley, Paul J. (2016) Dicarbonyl stress in clinical obesity. Glycoconjugates Journal, 33 (4). pp. 581-589. doi:10.1007/s10719-016-9692-0

Rabbani, Naila, Ashour, Amal and Thornalley, Paul J. (2016) Mass spectrometric determination of early and advanced glycation in biology. Glycoconjugates Journal, 33 (4). pp. 533-568. doi:10.1007/s10719-016-9709-8

Zhang, Fang, Masania, Jinit , Anwar, Attia, Xue, Mingzhan, Zehnder, Daniel, Kanji, Hemali, Rabbani, Naila and Thornalley, Paul J. (2016) The uremic toxin oxythiamine causes functional thiamine deficiency in end-stage renal disease by inhibiting transketolase activity. Kidney International, 90 (2). pp. 396-403. doi:10.1016/j.kint.2016.03.010

Rabbani, Naila, Xue, Mingzhan and Thornalley, Paul J. (2016) Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics. Glycoconjugates Journal, 33 . 513. doi:10.1007/s10719-016-9705-z

Xue, Mingzhan, Weickert, Martin O., Qureshi, S. A., Kandala, Ngianga-Bakwin, Anwar, Attia, Waldron, Molly, Shafie, Alaa, Messenger, David, Fowler, Mark, Jenkins, Gail, Rabbani, Naila and Thornalley, Paul J. (2016) Improved glycemic control and vascular function in overweight and obese subjects by glyoxalase 1 inducer formulation. Diabetes . db160153. doi:10.2337/db16-0153

Xue, Mingzhan, Momiji, Hiroshi, Rabbani, Naila, Barker, Guy C., Bretschneider, Till, Shmygol, Anatoly, Rand, D. A. (David A.) and Thornalley, Paul J. (2015) Frequency modulated translocational oscillations of Nrf2 mediate the antioxidant response element cytoprotective transcriptional response. Antioxidants & Redox Signaling, 23 (7). pp. 613-629. doi:10.1089/ars.2014.5962

Xue, Mingzhan, Momiji, Hiroshi, Rabbani, Naila, Bretschneider, Till, Rand, D. A. (David A.) and Thornalley, Paul J. (2015) Frequency modulated translocational oscillations of Nrf2, a transcription factor functioning like a wireless sensor. Biochemical Society Transactions, 43 (4). pp. 669-673. doi:10.1042/BST20150060

Duivenvoorde, Loes P. M., van Schothorst, Evert M., Derous, Davina, van der Stelt, Inge, Masania, Jinit , Rabbani, Naila, Thornalley, Paul J. and Keijer, Jaap (2015) Oxygen restriction as challenge test reveals early high-fat-diet-induced changes in glucose and lipid metabolism. Pfluegers Archiv, 467 (6). pp. 1179-1193. doi:10.1007/s00424-014-1553-8

Duivenvoorde, Loes P. M., van Schothorst, Evert M., Derous, Davina, van der Stelt, Inge, Masania, Jinit , Rabbani, Naila, Thornalley, Paul J. and Keijer, Jaap (2015) Oxygen restriction as challenge test reveals early high-fat-diet-induced changes in glucose and lipid metabolism. Pfluegers Archiv- European Journal of Physiology, 467 (6). pp. 1179-1193. doi:10.1007/s00424-014-1553-8

Ahmed, Usman, Anwar, Attia, Savage, Richard S., Costa, Matthew L., Mackay, N., Filer, Andrew, Raza, Karim, Watts, Richard, Winyard, P. G., Haigh, R. C., Thornalley, Paul J. and Rabbani, Naila (2015) Biomarker combination detects early-stage and discriminates osteoarthritis, rheumatoid arthritis and other inflammatory joint disease. Scientific Reports (5). L9259. doi:10.1038/srep09259

Rabbani, Naila and Thornalley, Paul J. (2015) Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease. Biochemical and Biophysical Research Communications, 458 (2). pp. 221-226. doi:10.1016/j.bbrc.2015.01.140

Rabbani, Naila and Thornalley, Paul J. (2015) Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease. Biochemical and biophysical research communications, Volume 458 (Number 2). pp. 221-226. doi:10.1016/j.bbrc.2015.01.140

Waris, Sahar, Winklhofer-Roob, Brigitte M., Roob, Johannes, M., Fuchs, Sebastian W., Souriji, Harald, Rabbani, Naila and Thornalley, Paul J. (2015) Increased DNA dicarbonyl glycation and oxidation markers in patients with type 2 diabetes and link to diabetic nephropathy. Journal of Diabetes Research, Volume 2015 . Article number 915486. doi:10.1155/2015/915486

Rabbani, Naila and Thornalley, Paul J. (2015) The hidden complexities in measurement of fructosyl-lysine and advanced glycation endproducts for risk prediction of vascular complications of diabetes. Diabetes, Volume 64 (Number 1). pp. 9-11. doi:10.2337/db14-1516

Ahmed, Usman, Thornalley, Paul J. and Rabbani, Naila (2015) Factors influencing the development and effectiveness of biomarkers in rheumatoid arthritis and osteoarthritis. International Journal of Clinical Rheumatology, 10 (5). pp. 313-316. doi:10.2217/ijr.15.37

Waris, Sahar, Winklhofer-Roob, Brigitte M., Roob, Johannes M., Fuchs, Sebastian W., Sourij, Harald, Rabbani, Naila and Thornalley, Paul J. (2015) Increased DNA dicarbonyl glycation and oxidation markers in patients with type 2 diabetes and link to diabetic nephropathy. Journal of diabetes research, 2015 . pp. 1-10. 915486. doi:10.1155/2015/915486

Godfrey, L. (Lisa), Yamada-Fowler, N. (Naomi), Smith, L. , Thornalley, Paul J. and Rabbani, Naila (2014) Arginine-directed glycation and decreased HDL plasma concentration and functionality. Nutrition & Diabetes, Volume 4 (Number 9). pp. 1-9. Article number e134. doi:10.1038/nutd.2014.31

Rabbani, Naila and Thornalley, Paul J. (2014) Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples. Nature Protocols, 9 . pp. 1969-1979. doi:10.1038/nprot.2014.129

Geoffrion, M., Du, X., Irshad, Zehra, Vanderhyden, B. C., Courville, K., Sui, G., D'Agati, V. D., Ott-Braschi, S., Rabbani, Naila, Thornalley, Paul J., Brownlee, M. and Milne, R. W. (2014) Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice. Physiological Reports, Volume 2 (Number 6). Article number e12043. doi:doi:10.14814/phy2.12043

Arai, Makoto, Nihonmatsu‑Kikuchi, Naomi, Itokawa, Masanari, Rabbani, Naila and Thornalley, Paul J. (2014) Measurement of glyoxalase activities. Biochemical Society Transactions, 42 (2). pp. 491-494. 491. doi:10.1042/BST20140010

Xue, Mingzhan, Rabbani, Naila and Thornalley, Paul J. (2014) Measurement of glyoxalase gene expression. Biochemical Society Transactions, 42 (2). pp. 495-499. 495. doi:10.1042/BST20140026

Rabbani, Naila, Xue, Mingzhan and Thornalley, Paul J. (2014) Activity, regulation, copy number and function in the glyoxalase system. Biochemical Society Transactions, Volume 42 (Number 2). pp. 419-424. doi:10.1042/BST20140008

Thornalley, Paul J. and Rabbani, Naila (2014) Assay of methylglyoxal and glyoxal and control of peroxidase interference. Biochemical Society Transactions, Volume 42 (Number 2). pp. 504-510. doi:10.1042/BST20140009

Rabbani, Naila and Thornalley, Paul J. (2014) Dicarbonyl proteome and genome damage in metabolic and vascular disease. Biochemical Society Transactions, Volume 42 (Number 2). pp. 425-32. doi:10.1042/BST20140018

Rabbani, Naila and Thornalley, Paul J. (2014) Glyoxalase Centennial conference : introduction, history of research on the glyoxalase system and future prospects. Biochemical Society Transactions, Volume 42 (Number 2). pp. 413-418. doi:10.1042/BST20140014

Ahmed, Usman, Thornalley, Paul J. and Rabbani, Naila (2014) Possible role of methylglyoxal and glyoxalase in arthritis. Biochemical Society Transactions, Volume 42 (Number 2). pp. 538-542. doi:10.1042/BST20140024

Lopez-Clavijo, Andrea, Duque-Daza, Carlos A., Romero-Canelón, Isolda, Barrow, Mark P., Kilgour, David P. A., Rabbani, Naila, Thornalley, Paul J. and O’Connor, Peter B. (2014) Study of an unusual advanced glycation end-product (AGE) derived from glyoxal using mass spectrometry. Journal of The American Society for Mass Spectrometry, Volume 25 (Number 4). pp. 673-683. doi:10.1007/s13361-013-0799-2

Thornalley, Paul J. and Rabbani, Naila (2014) Detection of oxidized and glycated proteins in clinical samples using mass spectrometry - a user's perspective. Biochimica et Biophysica Acta (BBA) - General Subjects, 1840 (2). pp. 818-829. doi:10.1016/j.bbagen.2013.03.025

Shaheen, Fozia, Shmygol, Anatoly, Rabbani, Naila and Thornalley, Paul J. (2014) A fluorogenic assay for methylglyoxal. Biochemical Society Transactions, Volume 42 (Number 2). pp. 548-555. doi:10.1042/BST20140028

Rabbani, Naila, Shaheen, Fozia, Anwar, Attia, Masania, Jinit and Thornalley, Paul J. (2014) Assay of methylglyoxal-derived protein and nucleotide AGEs. Biochemical Society Transactions, 42 (2). pp. 511-517. doi:10.1042/BST20140019

Shafie, Alaa, Xue, Mingzhan, Thornalley, Paul J. and Rabbani, Naila (2014) Copy number variation of glyoxalase I. Biochemical Society Transactions, Volume 42 (Number 2). pp. 500-503. doi:10.1042/BST20140011

Rabbani, Naila and Thornalley, Paul J. (2014) Special edition of Amino Acids of selected papers from the eleventh international symposium on the Maillard reaction, September 16–20, 2012. Amino Acids, Volume 46 (Number 2). p. 259. doi:10.1007/s00726-013-1635-5

Rabbani, Naila and Thornalley, Paul J. (2014) The critical role of methylglyoxal and glyoxalase 1 in diabetic nephropathy. Diabetes, Volume 63 (Number 1). pp. 50-52. doi:10.2337/db13-1606

Fleming, T., Theilen, T. M., Masania, Jinit , Wunderle, M., Karimian, J., Vitta, S., Bernauer, R., Bierhaus, A., Rabbani, Naila, Thornalley, Paul J., Kroll, J., Tyedmers, J., Nawrotzki, R., Herzig, S., Brownlee, M. and Nawroth, P. P. (2013) Aging-dependent reduction in Glyoxalase-I delays wound healing. Gerontology, 59 (5). pp. 427-437. doi:10.1159/000351628

Ajjan, R. A., Gamlen, T., Standeven, K. F., Mughal, S., Hess, K., Smith, K. A., Dunn, E. J., Anwar, M. M., Rabbani, Naila, Thornalley, Paul J., Philippou, H. and Grant, P. J. (2013) Diabetes is associated with posttranslational modifications in plasminogen resulting in reduced plasmin generation and enzyme-specific activity. Blood, Volume 122 (Number 1). pp. 134-142. doi:10.1182/blood-2013-04-494641

Klooster, Astrid, Larkin, James Robert, Wiersema-Buist, Janneke, Gans, Reinold O. B., Thornalley, Paul J., Navis, Gerjan, van Goor, Harry, Leuvenink, Henri G. D. and Bakker, Stephan J. L. (2013) Are brain and heart tissue prone to the development of thiamine deficiency? Alcohol, Volume 47 (Number 3). pp. 215-221. doi:10.1016/j.alcohol.2012.12.014

Duranton, F., Cohen, Gerald, De Smet, R., Rodriguez, Mariano, Jankowski, Joachim, Vanholder, Raymond and Argiles, Angel (2012) Normal and pathologic concentrations of uremic toxins. Journal of the American Society of Nephrology, 23 (7). pp. 1258-1270. doi:10.1681/ASN.2011121175

Rabbani, Naila, Antonysunil, Adaikalakoteswari, Rossing, Kasper, Rossing, Peter, Tarnow, Lise, Parving, Hans-Henrik and Thornalley, Paul J. (2012) Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria. Amino Acids, Vol.42 (No.5). pp. 1627-1639. doi:10.1007/s00726-011-0857-7

Xue, Mingzhan, Rabbani, Naila, Momiji, Hiroshi, Imbasi, Precious, Anwar, M. Maqsud, Kitteringham, Neil, Park, B. Kevin, Souma, Tomokazu, Moriguchi, Takashi, Yamamoto, Masayuki and Thornalley, Paul J. (2012) Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. The Biochemical journal, Vol.443 (No.1). pp. 213-22. doi:10.1042/BJ20111648

Rabbani, Naila and Thornalley, Paul J. (2012) Glycation research in amino acids : a place to call home. Amino Acids, Vol.42 (No.4). pp. 1087-1096. doi:10.1007/s00726-010-0782-1

Rabbani, Naila and Thornalley, Paul J. (2012) Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome. Amino Acids, Vol.42 (No.4). pp. 1133-1142. doi:10.1007/s00726-010-0783-0

Antonysunil, Adaikalakoteswari, Rabbani, Naila, Waspadji, Sarwono, Tjokroprawiro, Askandar, Kariadi, Sri H.K.S., Adam, John M.F. and Thornalley, Paul J. (2012) Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia — link to renal status, glycemic control and vascular inflammation. Diabetes Research and Clinical Practice, Vol.95 (No.3). pp. 415-424. doi:10.1016/j.diabres.2011.10.042

Thornalley, Paul J. and Rabbani, Naila (2012) Dietary and synthetic activators of the antistress gene response in treatment of renal disease. Journal of Renal Nutrition, 22 (1). pp. 195-202. doi:10.1053/j.jrn.2011.10.012

Rabbani, Naila and Thornalley, Paul J. (2012) Amino Acids Glycation Section. Amino Acids, Vol. 42 (No. 4). pp. 1085-1086. doi:10.1007/s00726-011-0956-5

Lopez-Clavijo, Andrea F., Barrow, Mark P., Rabbani, Naila, Thornalley, Paul J. and O’Connor, Peter B. (2012) Determination of types and binding sites of advanced glycation end products for substance P. Analytical Chemistry, Vol.84 (No.24). pp. 10568-10575. doi:10.1021/ac301583d

Larkin, James Robert, Zhang, F. (Fang), Godfrey, L. (Lisa), Molostvov, Guerman, Zehnder, Daniel, Rabbani, Naila and Thornalley, Paul J. (2012) Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes. PLoS One, Vol.7 (No.12). Article no. e53175. doi:10.1371/journal.pone.0053175

(2012) Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nature Medicine, Vol.18 (No.6). pp. 926-933. doi:10.1038/nm.2750

Perkins, Bruce A., Rabbani, Naila, Weston, Andrew J., Ficociello, Linda H., Antonysunil, Adaikalakoteswari, Niewczas, Monika, Warram, James, Krolewski, Andrzej S. and Thornalley, Paul J. (2012) Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes. PLoS One, Vol.7 (No.4). e35655. doi:10.1371/journal.pone.0035655

Rabbani, Naila and Thornalley, Paul J. (2011) Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy. Diabetes, Obesity and Metabolism, Volume 13 (Number 7). pp. 577-583. doi:10.1111/j.1463-1326.2011.01384.x

Kihm, L. P., Muller-Krebs, S., Klein, Julia, Ehrlich, G., Mertes, L., Gross, Marie-Luise, Antonysunil, Adaikalakoteswari, Thornalley, Paul J., Hammes, H.-P., Nawroth, P. P., Zeier, M. and Schwenger, Vedat (2011) Benfotiamine protects against peritoneal and kidney damage in peritoneal dialysis. Journal of the American Society of Nephrology, Vol.22 (No.5). pp. 914-926. doi:10.1681/ASN.2010070750

Xue, Mingzhan, Rabbani, Naila and Thornalley, Paul J. (2011) Glyoxalase in ageing. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 293-301. doi:10.1016/j.semcdb.2011.02.013

Rabbani, Naila and Thornalley, Paul J. (2011) Glyoxalase in diabetes, obesity and related disorders. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 309-317. doi:10.1016/j.semcdb.2011.02.015

Thornalley, Paul J. and Rabbani, Naila (2011) Glyoxalase in tumourigenesis and multidrug resistance. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 318-325. doi:10.1016/j.semcdb.2011.02.006

Thornalley, Paul J. (2011) Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems - role in ageing and disease. Drug Metabolism and Drug Interactions, Vol.23 (No.1-2). pp. 125-150. doi:10.1515/DMDI.2008.23.1-2.125

Rabbani, Naila and Thornalley, Paul J. (2011) The glyoxalase system — from microbial metabolism, through ageing to human disease and multidrug resistance. Seminars in Cell and Developmental Biology, Vol.22 (No.3). p. 261. doi:10.1016/j.semcdb.2011.02.014

Murphy, Michael P., Holmgren, Arne, Larsson, Nils-Göran, Halliwell, Barry, Chang, Christopher J., Kalyanaraman, Balaraman, Rhee, Sue Goo, Thornalley, Paul J., Partridge, Linda, Gems, David, Nyström, Thomas, Belousov, Vsevolod, Schumacker, Paul T. and Winterbourn, Christine C. (2011) Unraveling the biological roles of reactive oxygen species. Cell Metabolism, Volume 13 (Number 4). pp. 361-366. doi:10.1016/j.cmet.2011.03.010

Kurz, Alexander, Rabbani, Naila, Walter, Michael, Bonin, Michael, Thornalley, Paul J., Auburger, Georg and Gispert, Suzana (2011) Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress. Cellular and Molecular Life Sciences, Vol.68 (No.4). pp. 721-733. doi:10.1007/s00018-010-0483-7

Thornalley, Paul J. and Rabbani, Naila (2011) Protein damage in diabetes and uremia—identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect. Free Radical Research, Vol.45 (No.1). pp. 89-100. doi:10.3109/10715762.2010.534162

Rabbani, Naila, Godfrey, L. (Lisa), Xue, Mingzhan, Shaheen, Fozia, Geoffrion, M., Milne, Ross and Thornalley, Paul J. (2011) Glycation of LDL by methylglyoxal increases arterial atherogenicity : a possible contributor to increased risk of cardiovascular disease in diabetes. Diabetes, Vol.60 (No.7). pp. 1973-1980. doi:10.2337/db11-0085

Thornalley, Paul J., Waris, Sahar, Fleming, Thomas, Santarius, Thomas, Larkin, Sarah J., Winklhofer-Roob, Brigitte M., Stratton, Michael R. and Rabbani, Naila (2010) Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance. Nucleic Acids Research, Vol.38 (No.16). pp. 5432-5442. doi:10.1093/nar/gkq306

Santarius, Thomas, Bignell, Graham R., Greenman, Chris D., Widaa, Sara, Chen, Lina, Mahoney, Claire L., Butler, Adam, Edkins, Sarah, Waris, Sahar, Thornalley, Paul J., Futreal, P. Andrew and Stratton, Michael R. (2010) GLO1-a novel amplified gene in human cancer. Genes Chromosomes & Cancer, Vol.49 (No.8). pp. 711-725. doi:10.1002/gcc.20784

Karachalias, N., Babaei-Jadidi, R., Rabbani, Naila and Thornalley, Paul J. (2010) Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes. Diabetologia, Vol.53 (No.7). pp. 1506-1516. doi:10.1007/s00125-010-1722-z

Rabbani, Naila, Chittari, Madhu Varma, Bodmer, Charles W., Zehnder, Daniel, Ceriello, Antonio and Thornalley, Paul J. (2010) Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin. Diabetes, Vol.59 (No.4). pp. 1038-1045. doi:10.2337/db09-1455

Duran-Jimenez, Beatriz, Dobler, Darin, Moffatt, Sarah, Rabbani, Naila, Streuli, Charles H., Thornalley, Paul J., Tomlinson, David R. and Gardiner, Natalie J. (2009) Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes. Diabetes, Vol.58 (No.12). pp. 2893-2903. doi:10.2337/db09-0320

(2009) C-elegans as model for the study of high glucose-mediated life span reduction. Diabetes, Vol.58 (No.11). pp. 2450-2456. doi:10.2337/db09-0567

Bechtold, Ulrike, Rabbani, Naila, Mullineaux, Philip M. and Thornalley, Paul J. (2009) Quantitative measurement of specific biomarkers for protein oxidation, nitration and glycation in Arabidopsis leaves. Plant Journal, Vol.59 (No.4). pp. 661-671. doi:10.1111/j.1365-313X.2009.03898.x

Thornalley, Paul J. and Rabbani, Naila (2009) Highlights and hotspots of protein glycation in end-stage renal disease. Seminars in Dialysis, Vol.22 (No.4). pp. 400-404. doi:10.1111/j.1525-139X.2009.00589.x

(2009) The role of EUTox in uremic toxin research. Seminars in Dialysis, Vol.22 (No.4). pp. 323-328. doi:10.1111/j.1525-139X.2009.00574.x

Vanhorebeek, Ilse, Ellger, Bjoern, De Vos, Rita, Boussemaere, Magaly, Debaveye, Yves, Vander Perre, Sarah, Rabbani, Naila, Thornalley, Paul J. and Van den Berghe, Greet (2009) Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness. Critical Care Medicine, Vol.37 (No.4). pp. 1355-1364. doi:10.1097/CCM.0b013e31819cec17

Rabbani, Naila, Alam, S. S., Riaz, S., Larkin, J. R., Akhtar, M. W., Shafi, T. and Thornalley, Paul J. (2009) High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. Diabetologia, Vol.52 (No.2). pp. 208-212. doi:10.1007/s00125-008-1224-4

Wendler, Alexandra, Irsch, Thorsten, Rabbani, Naila, Thornalley, Paul J. and Krauth-Siegel, R. Luise (2009) Glyoxalase II does not support methylglyoxal detoxification but serves as a general trypanothione thioesterase in African trypanosomes. Molecular and Biochemical Parasitology, Vol.163 (No.1). pp. 19-27. doi:10.1016/j.molbiopara.2008.09.005

Thornalley, Paul J. and Rabbani, Naila (2009) Highlights and hotspots of protein glycation in end-stage renal disease. Seminars in Dialysis, 22 (4). pp. 400-404. doi:10.1111/j.1525-139X.2009.00589.x

(2009) The role of EUTox in uremic toxin research. Seminars in Dialysis, 22 (4). pp. 323-328. doi:10.1111/j.1525-139X.2009.00574.x

Xue, Mingzhan, Qian, Qingwen, Antonysunil, Adaikalakoteswari, Rabbani, Naila, Babaei-Jadidi, Roya and Thornalley, Paul J. (2008) Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes, Volume 57 (Number 10). pp. 2809-2817. doi:10.2337/db06-1003

(2008) Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans. Aging Cell, Vol.7 (No.2). pp. 260-269. doi:10.1111/j.1474-9726.2008.00371.x

Fleming, Thomas, Rabbani, Naila and Thornalley, Paul J. (2008) Preparation of nucleotide advanced glycation endproducts - Imidazopurinone adducts formed by glycation of deoxyguanosine with glyoxal and methylglyoxal. New York Academy of Sciences. Annals, Volume 1126 . pp. 280-282. doi:10.1196/annals.1433.037

Vanhorebeek, I., Ellger, B., Gunst, J., Boussemaere, M., Debaveye, Y., Rabbani, Naila, Thornalley, Paul J., Schetz, M. and Van den Berghe, G. (2008) Mechanisms of kidney protection by intensive insulin therapy during critical illness. Critical Care, Volume 12 (Supplement 2). Article number P151. doi:10.1186/cc6372

Rabbani, Naila and Thornalley, Paul J. (2008) Assay of 3-nitrotyrosine in tissues and body fluids by liquid chromatography with tandem mass spectrometric detection. Methods in Enzymology, Volume 440 . pp. 337-359. doi:10.1016/S0076-6879(07)00822-1

Rabbani, Naila, Sebekova, K., Sebekova, K., Heidland, A. and Thornalley, Paul J. (2007) Accumulation of free adduct glycation, oxidation, and nitration products follows acute loss of renal function. Kidney International, Vol.72 (No.9). pp. 1113-1121. doi:10.1038/sj.ki.5002513

Yao, Dachun, Taguchi, Tetsuya, Matsumura, Takeshi, Pestell, Richard, Edelstein, Diane, Giardino, Ida, Suske, Guntram, Rabbani, Naila, Thornalley, Paul J., Sarthy, Vijay P., Hammes, Hans-Peter and Brownlee, Michael (2007) High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. Journal of Biological Chemistry, Vol.282 (No.42). pp. 31038-31045. doi:10.1074/jbc.M704703200

Thornalley, Paul J., Babaei-Jadidi, R., Al Ali, H., Rabbani, Naila, Antonysunil, Adaikalakoteswari, Larkin, J. R., Ahmed, A., Rayman, G. and Bodmer, C. W. (2007) High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease. Diabetologia, Vol.50 (No.10). pp. 2164-2170. doi:10.1007/s00125-007-0771-4

Thornalley, Paul J. and Rabbani, Naila (2001) Detection of oxidized and glycated proteins in clinical samples using mass spectrometry — A user's perspective. Biochimica et Biophysica Acta (BBA) - General Subjects, Volume 1840 (Number 2). pp. 1818-829. doi:10.1016/j.bbagen.2013.03.025

Book Item

Rabbani, Naila and Thornalley, Paul J. (2016) Glycation of proteins. In: Griffiths, J. R. and Unwin, R. D. , (eds.) Analysis of Protein Post-Translational Modifications by Mass Spectrometry. Hoboken, NJ, USA: John Wiley & Sons, Inc., , pp. 307-332. ISBN 9781119045854

Rabbani, Naila and Thornalley, Paul J. (2014) Glycation- and/or Polyol pathway-inducing complications. In: Reference Module in Biomedical Sciences. Elsevier . ISBN 9780128012383

Rabbani, Naila and Thornalley, Paul J. (2012) Dicarbonyls (Glyoxal, Methylglyoxal, and 3-Deoxyglucosone). In: Niwa, T., (ed.) Uremic Toxins. Wiley Series on Mass Spectrometry . John Wiley & Sons, Inc., pp. 177-192. ISBN 9781118135136

Rabbani, Naila and Thornalley, Paul J. (2012) Advanced Glycation Endproducts (AGEs). In: Niwa, T., (ed.) Uremic Toxins. Wiley Series on Mass Spectrometry . John Wiley & Sons, Inc., pp. 293-304. ISBN 9781118135136

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2011) Methodologies for in-vitro and in-vivo activity of bioactive compounds. In: Terry, Leon A. (Leon Alexander), (ed.) Health-promoting properties of fruits and vegetables. Wallingford, Oxfordshire ; Cambridge, MA: CAB. ISBN 9781845935283

Thornalley, Paul J. and Rabbani, Naila (2011) Thiamine in diabetic renal disease - dietary insufficiency, renal washout, anti-stress gene response, therapeutic supplements, risk predictor and link to genetic susceptibility. In: Miyata, Toshio and Eckardt, Kai-Uwe and Nangaku, Masaomi, (eds.) Studies on renal disorders. Oxidative stress in applied basic research and clinical practice . New York: Humana Press, pp. 93-104. ISBN 9781607618577

Thornalley, Paul J. and Rabbani, Naila (2010) Oxidation modification of proteins : an overview. In: Aldini, G. and Yeum, K. -J. and Niki, E. and Russell, R. M., (eds.) Biomarkers for antioxidant defense and oxidative damage : principles and practical applications. Ames, Iowa: Wiley-Blackwell, pp. 137-156. ISBN 9780813815350

Xue, Mingzhan, Antonysunil, Adaikalakoteswari, Rabbani, Naila and Thornalley, Paul J. (2009) Protein damage in the ageing process : advances in quantitation and the importance of enzymatic defences. In: Redox metabolism and longevity relationships in animals and plants. SEB experimental biology series, Vol.62 . New York ; Abingdon [England]: Taylor & Francis Group, pp. 227-265. ISBN 9780415419543

Conference Item

Ahmed, Usman, Rabbani, Naila, Filer, Andrew, Watts, Richard, Raza, Karim and Thornalley, Paul J. (2010) Changes in advanced glycation endproducts in synovial fluid in early resolving arthritis and early and established rheumatoid arthritis. In: Annual Meeting of the British Society Rheumatology/Spring Meeting of British Health Professional in Rheumatology, Birmingham, Englad, April 21-23, 2010. Published in: Rheumatology, Vol.49 (No.Suppl. 1). I161-I161. ISSN 1462-0324. doi:10.1093/rheumatology/keq736

Thornalley, Paul J. and Rabbani, Naila (2010) Dicarbonyls in cola drinks sweetened with sucrose or high fructose corn syrup. In: International Symposium on the Maillard Reaction, Palm Cove, Australia, 29-31 Aug 2009. Published in: Maillard Reaction: interface between aging, nutrition and metabolism pp. 158-163. ISSN 9781849730792.

Rabbani, Naila, Chittari, M. V., Zehnder, Daniel, Ceriello, Antonio and Thornalley, Paul J. (2009) High dose metformin therapy reduces glycation and oxidative damage to apolipoprotein B100 and may decelerate atherosclerosis in patients with type 2 diabetes. In: 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Vienna, AUSTRIA, SEP 30-OCT 02, 2009. Published in: Diabetologia, Vol.52 (Suppl. 1). S498-S499. ISSN 0012-186X.

Vanhorebeek, Ilse, Gunst, Jan, Ellger, Bjoern, Boussemaere, Magaly, Lerut, Evelyne, Debaveye, Yves, Rabbani, Naila, Thornalley, Paul J., Schetz, Miet and Van den Berghe, Greet (2009) Hyperglycemic kidney damage in an animal model of prolonged critical illness. In: 90th Annual Meeting of the Endocrine-Society, San Francisco, CA, June 15-18, 2008. Published in: Kidney International, Vol.76 (No.5). pp. 512-520. ISSN 0085-2538. doi:10.1038/ki.2009.217

Stoyanov, S. B., Fleming, T., Humpert, P. M., Sauer, S., Rabbani, Naila, Edelstein, D., Thornalley, Paul J., Reeh, P., Brownlee, M., Nawroth, P. P. and Bierhaus, A. (2009) Loss of glyoxalase-1 promotes hyperalgesia in early diabetic neuropathy. In: 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Vienna, Austria, September 30-October 02, 2009. Published in: Diabetologia, Vol.52 (Suppl.1). S444-S445. ISSN 0012-186X.

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2009) Involvement of transcription factor nrf2 and antioxidant response element linked gene expression in countering oxidative stress in diabetes. In: 34th Congress of the Federation of European Biochemical Societies, Prague, Czech Republic, July 04-09, 2009. Published in: FEBS Journal, Vol.276 (Suppl. 1). pp. 79-80. ISSN 1742-464x. doi:10.1111/j.1742-4658.2009.07046.x

Rabbani, Naila and Thornalley, Paul J. (2009) Quantitation of markers of protein damage by glycation, oxidation, and nitration in peritoneal dialysis. In: 12th Congress of the International-Society-for-Peritoneal-Dialysis, Istanbul, Turkey, JUN 20-24, 2008. Published in: Peritoneal Dialysis International, Vol.29 (Suppl. 2). S51-S56. ISSN 0896-8608.

Thornalley, Paul J. (2009) Glycation and oxidative damage in developing embryos of high fat diet-fed mice. In: Biannual International Symposium, Cairns, Australia, 29-31 August 2009

Thornalley, Paul J. (2009) Glycation and the antistress gene response. In: Biannual International Symposium, Cairns, Australia, 29-31 August 2009

Ahmed, Usman, Rabbani, Naila, Costa, Matthew L., Watts, R. and Thornalley, Paul J. (2009) Increasing concentrations of proteolytic debris of glycated and oxidised proteins in patients with increasing severity of osteoarthritis. In: British Orthopaedic Research Society Annual Meeting, Newcastle-upon-Tyne, UK, 22-23 June 2009

Karachalias, N., Babaei-Jadidi, R., Rabbani, Naila and Thornalley, Paul J. (2009) Prevention of advanced glycation endproduct accumulation in renal glomeruli, retina and nerve in experimental diabetes by high dose thiamine and benfotiamine. In: Diabetes UK's Annual Professional Conference, SECC, Glasgow, UK, 11-13 March 2009 p. 70.

Yamada-Fowler, N. (Naomi), Godfrey, L. (Lisa), Thornalley, Paul J. and Rabbani, Naila (2009) Quantitation of the glycation-induced changes in HDL2 and HDL3 by liquid chromatography with tandem mass spectrometric detection. In: Diabetes UK's Annual Professional Conference, SECC, Glasgow, UK, 11-13 March 2009 p. 70.

Riaz, Samreen, Alam, Saadia Shahzad, Rabbani, Naila, Thornalley, Paul J. and Akhtar, Waheed (2009) Study of protein biomarker for diabetes type 2 and role of thiamien on their levels. In: 86th Annual Meeting of the Physiological Society of Japan, Kyoto, Japan, July 27–August 1, 2009. Published in: Journal of Physiological Sciences, Vol.59 (Suppl. 1). p. 506. ISSN 1880-6546.

Thornalley, Paul J. and Rabbani, Naila (2009) Thiamine and benfotiamine therapy for the prevention of diabetic nephropathy. In: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options ; international expert workshop, Rome, Italy, Sep 2008. Published in: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options ISSN 9783131461414.

Rabbani, Naila and Thornalley, Paul J. (2009) Thiamine deficiency and renal function in diabetes. In: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options ; international expert workshop, Rome, Italy, Sep 2008. Published in: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options pp. 18-25. ISSN 9783131461414.

Rabbani, Naila and Thornalley, Paul J. (2008) Dicarbonyls linked to damage in the powerhouse : glycation of mitochondrial proteins and oxidative stress. In: 3rd Intracellular Proteolysis Meeting, Canary Isl, Spain, Mar 05-07, 2008. Published in: Biochemical Society Transactions, Vol.36 (Pt.5). pp. 1045-1050. ISSN 0300-5127. doi:10.1042/BST0361045

Larkin, J. R. and Thornalley, Paul J. (2008) High glucose causes a decrease in expression of thiamine transporters in human proximal tubule epithelial cells in vitro. In: 44th Annual Meeting of the European Association for the Study of Diabetes, Rome, Italy, 7 - 11 September 2008. Published in: Diabetologia, Vol.51 (Suppl.1). S97-S97. ISSN 0012-186X.

Rabbani, Naila and Thornalley, Paul J. (2008) Increased protein damage by advanced glycation endproducts and oxidation adducts in low density lipoprotein of type 2 diabetic patients. In: 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S525-S525. ISSN 0012-186X.

Xue, Mingzhan, Thornalley, Paul J. and Rabbani, Naila (2008) LDL glycated by methylglyoxal to physiological extent in vitro has increased binding of proteoglycan without impairment of LDL receptor binding. In: 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S299-S299. ISSN 0012-186X.

Thornalley, Paul J., Qian, Q. and Rabbani, Naila (2008) Prevention of dicarbonyl stress induced by hyperglycaemia in microvascular endoethelial cells by sulforaphane. In: 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S524-S524. ISSN 0012-186X.

Antonysunil, Adaikalakoteswari, Perkins, B., Krolewski, A. S., Rabbani, Naila and Thornalley, Paul J. (2008) Thiamine status and risk of early renal function decline in type 1 diabetic patients. In: 43rd General Assembly of the European Association for the Study of Diabetes, Amsterdam, 20 September 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S98-S98. ISSN 0012-186X.

Ahmed, Usman, Dobler, Darin, Larkin, Sarah J., Rabbani, Naila and Thornalley, Paul J. (2008) Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro. In: 9th International Symposium on the Maillard Reaction, Munich, Germany, Sep, 2007. Published in: New York Academy of Sciences. Annals, Vol.1126 pp. 262-264. ISBN 978-1-57331-719-1. ISSN 0077-8923. doi:10.1196/annals.1433.035

Rabbani, Naila and Thornalley, Paul J. (2008) The dicarbonyl proteome - proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease. In: 9th International Symposium on the Maillard Reaction, Munich, Germany, Sep, 2007. Published in: Annals of the New York Academy of Sciences, Volume 1126 pp. 124-127. ISBN 978-1-57331-719-1. ISSN 0077-8923. doi:10.1196/annals.1433.043

Klooster, Astrid, Leuvenink, Henri G. D., Gans, Rijk O. B., van Goor, Harry, Thornalley, Paul J., Navis, Gerjan and Bakker, Stephan J. L. (2008) Thiamine deficiency amerliorates renal ischaemia-reperfusion injury : role for impaired machrophage accumulation. In: American Society of Nephrology 41st Annual Meeting & Scientific Exposition, Philadelphia, PA, 4-9 Nov 2008

Thornalley, Paul J. (2007) Glycation and the enzymatic defence against glycation in the ageing process. In: Annual Main Meeting of the Society for Experimental Biology, Glasgow, Scotland, March 31 - April 4, 2007. Published in: Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.146 (No.4 Supplement). S57-S57. ISSN 1095-6433. doi:10.1016/j.cbpa.2007.01.046

Morcos, M., Morcos, M., Sayed, A., Pfisterer, F., Kukudov, G., El Baki, R. Abd, Rabbani, Naila, Du, X., Hutter, H., Thornalley, Paul J., Baynes, J. and Thorpe, S. (2007) Life extension in Caenorhabditis elegans by overexpression of Glyoxalase I - A mechanistic integration of protein damage by glycation, oxidation and nitratio. In: Annual Main Meeting of the Society for Experimental Biology, Glasgow, Scotland, March 31 - April 4, 2007. Published in: Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.146 (No.4 Supplement). S59-S59. ISSN 1095-6433. doi:10.1016/j.cbpa.2007.01.050

Xue, M. and Thornalley, Paul J. (2007) Sulforaphane suppresses reactive oxygen species and induces transcriptional activation of antioxidant response element related genes expression in human BJ-5ta fibroblasts. In: Annual Main Meeting of the Society for Experimental Biology, Glasgow, Scotland, March 31 - April 4, 2007. Published in: Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.146 (No.4 Supplement). S55-S56. ISSN 1095-6433. doi:10.1016/j.cbpa.2007.01.041

Antonysunil, Adaikalakoteswari, Thornalley, Paul J., Muthuswamy, B., Radhakrishnan, R., Raj, D. and Viswanathan, M. (2007) Telomere shortening in subjects with impaired glucose tolerance and patients with diabetic macro-angiopathy. In: Annual Main Meeting of the Society for Experimental Biology, Glasgow, Scotland, March 31 - April 4, 2007. Published in: Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.146 (No.4 Supplement). S63-S64. ISSN 1095-6433. doi:10.1016/j.cbpa.2007.01.061

Antonysunil, Adaikalakoteswari, Thornalley, Paul J., Muthuswamy, B., Radhakrishnan, R., Raj, D. and Viswanathan, M. (2007) Telomere shortening in subjects with impaired glucose tolerance and patients with diabetic macroangiopathy. In: Annual Main Meeting of the Society for Experimental Biology, Glasgow, Scotland, March 31 - April 4, 2007. Published in: Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.146 (No.4 Supplement). S59-S59. ISSN 1095-6433. doi:10.1016/j.cbpa.2007.01.051

Journal Item

Ahmed, Usman, Thornalley, Paul J. and Rabbani, Naila (2015) New development in a blood-based diagnostic test for early-stage arthritis. Biomarkers in Medicine, 9 (10). pp. 943-945. doi:10.2217/bmm.15.77

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2011) Role of NRF2 and the antistress gene response in countering oxidative stress in diabetes mellitus. Clinical Chemistry and Laboratory Medicine, Vol.49 (Supp.1). S52-S52.

Thornalley, Paul J. and Rabbani, Naila (2010) Therapy: vitamin B6, B9 and B12 in diabetic nephropathy-beware. Nature Reviews Endocrinology, Vol.6 (No.9). pp. 477-478. doi:10.1038/nrendo.2010.124

Thornalley, Paul J., Babaei-Jadidi, R., Karachalias, N. and Rabbani, Naila (2010) Prevention of decline in glycaemic control in streptozotocin-induced diabetic rats by thiamine but not by Benfotiamine. Diabetic Medicine, Vol.27 (No.S1). p. 74. doi:10.1111/j.1464-5491.2009.02936.x

Rabbani, Naila, Alam, S. S., Riaz, S., Larkin, J. R., Akhtar, M. W., Shafi, T. and Thornalley, Paul J. (2009) Thiamine in diabetic nephropathy: a novel treatment modality? Reply to Alkhalaf A, Kleefstra N, Groenier KH et al. [letter]. Diabetologia, Vol.52 (No.6). pp. 1214-1216. doi:10.1007/s00125-009-1334-7

Klooster, A., Larkin, J. R., Antonysunil, Adaikalakoteswari, Gans, R. O. B., van Goor, H., Thornalley, Paul J., Rabbani, Naila, Navis, G., Leuvenink, H. G. D. and Bakker, S. J. L. (2009) Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats. NDT Plus, Vol.2 (No.2). pp. 182-183. doi:10.1093/ndtplus/sfn194

Perkins, B., Rabbani, Naila, Weston, A., Antonysunil, Adaikalakoteswari, Ficociello, Linda H., Warram, James, Krolewski, A. S. and Thornalley, Paul J. (2008) Early renal function decline in type 1 diabetes is associated with excess urinary excretion of markers of protein damage. Diabetes, Vol.57 . A210-A210.

(2007) Review on uraemic toxins III: recommendations for handling uraemic retention solutes in vitro - towards a standardized approach for research on uraemia. Nephrology, Dialysis, Transplantation, Vol.22 (No.12). pp. 3381-3390. doi:10.1093/ndt/gfm210

Thornalley, Paul J. (2007) Dietary AGEs and ALEs and risk to human health by their interaction with the receptor for advanced glycation endproducts (RAGE) - an introduction. Molecular Nutrition and Food Research, Vol.51 (No.9). pp. 1107-1110. doi:10.1002/mnfr.200700017