2021

Newman, Hector, Krajnc, Alen, Bellini, Dom, Eyermann, Charles J., Boyle, Grant A., Paterson, Neil G., McAuley, Katherine E., Lesniak, Robert, Gangar, Mukesh, von Delft, Frank, Brem, Jürgen, Chibale, Kelly, Schofield, Christopher J. and Dowson, Christopher G. (2021) High-throughput crystallography reveals boron-containing inhibitors of a Penicillin-binding protein with di- and tricovalent binding modes. Journal of Medicinal Chemistry, 64 (15). pp. 11379-11394. doi:10.1021/acs.jmedchem.1c00717

2020

(2020) Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion. Chemical Science, 11 (39). pp. 10792-10801. doi:10.1039/D0SC01232G

2019

Cain, Ricky, Salimraj, Ramya, Punekar, Avinash S., Bellini, Dom, Fishwick, Colin W. G., Czaplewski, Lloyd, Scott, David J., Harris, Gemma, Dowson, Christopher G., Lloyd, Adrian J. and Roper, David I. (2019) Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase. Journal of Medicinal Chemistry, 62 (21). pp. 9703-9717. doi:10.1021/acs.jmedchem.9b01131

Bellini, Dom, Koekemoer, Lizbé, Newman, Hector and Dowson, Christopher G. (2019) Novel and improved crystal structures of H. influenzae, E. coli and P. aeruginosa penicillin-binding protein 3 (PBP3) and N. gonorrhoeae PBP2 : toward a better understanding of β-Lactam target-mediated resistance. Journal of Molecular Biology, 431 (18). pp. 3501-3519. doi:10.1016/j.jmb.2019.07.010

(2019) Rapid covalent-probe discovery by electrophile-fragment screening. Journal of the American Chemical Society, 141 (22). pp. 8951-8968. doi:10.1021/jacs.9b02822

Bartho, Joseph D., Demitri, Nicola, Bellini, Dom, Flachowsky, Henryk, Peil, Andreas, Walsh, Martin A. and Benini, Stefano (2019) The structure of Erwinia amylovora AvrRpt2 provides insight into protein maturation and induced resistance to fire blight by Malus × robusta 5. Journal of Structural Biology, 206 (2). pp. 233-242. doi:10.1016/j.jsb.2019.03.010

2018

Ratamero, Erick Martins, Bellini, Dom, Dowson, Christopher G. and Römer, Rudolf A. (2018) Touching proteins with virtual bare hands : visualizing protein–drug complexes and their dynamics in self-made virtual reality using gaming hardware. Journal of Computer-Aided Molecular Design, 32 (6). pp. 703-709. doi:10.1007/s10822-018-0123-0

Salomone-Stagni, Marco, Bartho, Joseph D., Polsinelli, Ivan, Bellini, Dom, Walsh, Martin A., Demitri, Nicola and Benini, Stefano (2018) A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora. Journal of Structural Biology, 202 (3). pp. 236-249. doi:10.1016/j.jsb.2018.02.002