Huang, Chuan, Zabala, Daniel, de los Santos, Emmanuel, Song, Lijiang, Corre, Christophe, Alkhalaf, Lona M. and Challis, Gregory L. (2023) Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis. Nucleic Acids Research, 51 (3). pp. 1488-1499. doi:10.1093/nar/gkad009 ISSN 1362-4962.

Moore, Simon J., Lai, Hung-En, Chee, Soo-Mei, Toh, Ming, Coode, Seth, Chengan, Kameshwari, Capel, Patrick, Corre, Christophe, de los Santos, Emmanuel L. C. and Freemont, Paul S. (2021) A streptomyces venezuelae cell-free toolkit for synthetic biology. ACS Synthetic Biology, 10 (2). pp. 402-411. doi:10.1021/acssynbio.0c00581 ISSN 2161-5063.

Perez Ortiz, Gustavo, Sidda, John D., de los Santos, Emmanuel L. C., Hubert, Catherine B. and Barry, Sarah M. (2021) In vitro elucidation of the crucial but complex oxidative tailoring steps in rufomycin biosynthesis enables one pot conversion of rufomycin B to rufomycin C. Chemical Communications, 57 (89). pp. 11795-11798. doi:10.1039/d1cc04794a ISSN 1359-7345.

Kosol, Simone, Gallo, Angelo, Griffiths, Daniel, Valentic, Timothy R., Masschelein, Joleen, Jenner, Matthew, de los Santos, Emmanuel L. C., Manzi, Lucio, Sydor, Paulina K., Rea, Dean, Zhou, Shanshan, Füllöp, Vilmos, Oldham, Neil J., Tsai, Shiou-Chuan, Challis, Gregory L. and Lewandowski, Józef R. (2019) Structural basis for chain release from the enacyloxin polyketide synthase. Nature Chemistry, 11 . 913-923 . doi:10.1038/s41557-019-0335-5 ISSN 1755-4330.

de los Santos, Emmanuel L. C. (2019) NeuRiPP : neural network identification of RiPP precursor peptides. Scientific Reports, 9 (1). 13406. doi:10.1038/s41598-019-49764-z ISSN 2045-2322.

Kosol, Simone, Gallo, Angelo, Griffiths, Daniel, Valentic, Timothy R., Masschelein, Joleen, Jenner, Matthew, de los Santos, Emmanuel L. C., Manzi, Lucio, Sydor, Paulina K., Rea, Dean, Zhou, Shanshan, Fülöp, Vilmos, Oldham, Neil J., Tsai, Shiou-Chuan, Challis, Gregory L. and Lewandowski, Józef R. (2019) Data for Structural basis for chain release from the enacyloxin polyketide synthase. [Dataset]

Zhou, Shanshan, Song, Lijiang, Masschelein, Joleen, Sumang, Felaine A. M., Papa, Irene A., Zulaybar, Teofila O., Custodio, Aileen B., Zabala, Daniel, Alcantara, Edwin P., Emmanuel de los Santos, L. C. and Challis, Gregory L. (2019) Pentamycin biosynthesis in Philippine Streptomyces sp. S816 : cytochrome P450-catalyzed installation of the C-14 hydroxyl group. ACS Chemical Biology, 14 (6). pp. 1305-1309. doi:10.1021/acschembio.9b00270 ISSN 1554-8929.

Perry, Christopher, de los Santos, Emmanuel L. C., Alkhalaf, Lona M. and Challis, Gregory L. (2018) Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis. Natural Product Reports, 35 (7). pp. 622-632. doi:10.1039/c8np00004b ISSN 0265-0568.

Bowyer, Jack E., LC. de los Santos, Emmanuel, Styles, Kathryn, Fullwood, Alex, Corre, Christophe and Bates, Declan (2017) Modeling the architecture of the regulatory system controlling methylenomycin production in Streptomyces coelicolor. Journal of Biological Engineering, 11 (1). 30. doi:10.1186/s13036-017-0071-6 ISSN 1754-1611.

Blin, Kai, Wolf, Thomas, Chevrette, Marc G., Lu, Xiaowen, Schwalen, Christopher J., Kautsar, Satria A., Suarez Duran, Hernando G., Emmanuel de los Santos, L. C., Kim, Hyun Uk, Nave, Mariana, Dickschat, Jeroen S., Mitchell, Douglas A., Shelest, Ekaterina, Breitling, Rainer, Takano, Eriko, Lee, Sang Yup, Weber, Tilmann and Medema, Marnix H. (2017) antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification. Nucleic Acids Research . doi:10.1093/nar/gkx319 ISSN 0305-1048.

Emmanuel de los Santos, L. C. and Challis, Gregory L. (2017) clusterTools : proximity searches for functional elements to identify putative biosynthetic gene clusters. UNSPECIFIED. Cold Spring Harbor Labs Journals. (Submitted)

Awodi, U. R., Ronan, Jade L., Masschelein, Joleen, Emmanuel de los Santos, L. C. and Challis, Gregory L. (2017) Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis. Chemical Science, 8 (1). pp. 411-415. doi:10.1039/C6SC02803A ISSN 2041-6520.

Zhou, Shanshan, Alkhalaf, Lona M., Emmanuel de los Santos, L. C. and Challis, Gregory L. (2016) Mechanistic insights into class B radical-S-adenosylmethionine methylases : ubiquitous tailoring enzymes in natural product biosynthesis. Current Opinion in Chemical Biology, 35 . pp. 73-79. doi:10.1016/j.cbpa.2016.08.021 ISSN 1367-5931.

Emmanuel de los Santos, L. C., Meyerowitz, Joseph T., Mayo, Stephen L. and Murray, Richard M. (2016) Engineering transcriptional regulator effector specificity using computational design and in vitrorapid prototyping : developing a vanillin sensor. ACS Synthetic Biology, 5 (4). pp. 287-295. doi:10.1021/acssynbio.5b00090 ISSN 2161-5063.

Hsiao, Victoria, Emmanuel de los Santos, L. C., Whitaker, Weston R., Dueber, John E. and Murray, Richard M. (2015) Design and implementation of a biomolecular concentration tracker. ACS Synthetic Biology, 4 (2). pp. 150-161. doi:10.1021/sb500024b ISSN 2161-5063.

Emmanuel de los Santos, L. C., Hsiao, V., Whitaker, W. R., Dueber, J. E. and Murray, Richard M. (2013) Design and implementation of a biomolecular circuit for tracking protein concentration. In: American Control Conference 2013, Washington, DC, 17-19 Jun 2013. Published in: Proceedings of American Control Conference 2013 pp. 2290-2294.