Journal Article

Franks, W. Trent, Tognetti, Jacqueline and Lewandowski, Józef R. (2023) Slice & Dice : nested spin–lattice relaxation measurements. Physical Chemistry Chemical Physics . doi:10.1039/d2cp03458a ISSN 1463-9084. (In Press)

Tognetti, Jacqueline, Franks, W. Trent, Lewandowski, Józef Romuald and Brown, Steven P. (2022) Optimisation of 1H PMLG homonuclear decoupling at 60 kHz MAS to enable 15N-1H through-bond heteronuclear correlation solid-state NMR spectroscopy. Physical Chemistry Chemical Physics, 24 (34). pp. 20258-20273. doi:10.1039/D2CP01041K ISSN 1463-9076.

Franks, W. Trent, Tatman, Ben P., Trenouth, Jonah and Lewandowski, Józef R. (2021) Dipolar order parameters in large systems with fast spinning. Frontiers in Molecular Biosciences, 8 . 791026. doi:10.3389/fmolb.2021.791026 ISSN 2296-889X.

Szell, Patrick M. J., Lewandowski, Józef R., Blade, Helen, Hughes, Leslie P., Nilsson Lill, Sten O. and Brown, Steven P. (2021) Taming the dynamics in a pharmaceutical by cocrystallization : investigating the impact of the coformer by solid-state NMR. CrystEngComm, 23 (39). pp. 6859-6870. doi:10.1039/D1CE01084K ISSN 1466-8033.

Tognetti, Jacqueline, Franks, W. Trent, Gallo, Angelo and Lewandowski, Józef R. (2021) Accelerating 15N and 13C R1 and R1q relaxation measurements by multiple pathway solid-state NMR experiments. Journal of Magnetic Resonance, 331 . 107049. doi:10.1016/j.jmr.2021.107049 ISSN 1090-7807.

Fage, Christopher, Kosol, Simone, Jenner, Matthew, Öster, Carl, Gallo, Angelo, Kaniusaite, Milda, Steinbach, Roman, Staniforth, Michael, Stavros, Vasilios G., Marahiel, Mohamed A., Cryle, Max J. and Lewandowski, Józef R. (2021) Communication breakdown : dissecting the COM interfaces between the subunits of nonribosomal peptide synthetases. ACS Catalysis, 11 . pp. 10802-10813. doi:10.1021/acscatal.1c02113 ISSN 2155-5435.

Baker, Alexander, Richards, Sarah-Jane, Guy, Collette S., Congdon, Thomas R., Hasan, Muhammad, Zwetsloot, Alexander J., Gallo, Angelo, Lewandowski, Józef R., Stansfeld, Phillip J., Straube, Anne, Walker, Marc, Chessa, Simona, Pergolizzi, Giulia, Dedola, Simone, Field, Robert A. and Gibson, Matthew I. (2020) The SARS-COV-2 spike protein binds sialic acids and enables rapid detection in a lateral flow point of care diagnostic device. ACS Central Science, 6 (11). pp. 2046-2052. doi:10.1021/acscentsci.0c00855 ISSN 2374-7951.

Page, Samuel J., Gallo, Angelo, Brown, Steven P., Lewandowski, Józef R., Hanna, John V. and Franks, W. Trent (2020) Simultaneous MQMAS NMR experiments for two half-integer quadrupolar nuclei. Journal of Magnetic Resonance, 320 . 106831. doi:10.1016/j.jmr.2020.106831 ISSN 1090-7807.

Mann, Sarah K., Devgan, Mohit K., Franks, W. Trent, Huband, Steven, Chan, Chi Long, Griffith, Jeraime, Pugh, David, Brooks, Nicholas J., Welton, Tom, Pham, Tran N., McQueen, Lisa L., Lewandowski, Józef R. and Brown, Steven P. (2020) MAS NMR investigation of molecular order in an ionic liquid crystal. Journal of Physical Chemistry B, 124 (24). pp. 4975-4988. doi:10.1021/acs.jpcb.0c02328 ISSN 1520-6106.

Gyton, Matthew R., Kynman, Amy E., Leforestier, Baptiste, Gallo, Angello, Lewandowski, Józef R. and Chaplin, Adrian B. (2020) Isolation and structural characterisation of rhodium(III) η2–fluoroarene complexes : experimental verification of predicted regioselectivity. Dalton Transactions, 49 . pp. 5791-5793. doi:10.1039/D0DT01137A ISSN 1477-9226.

Mann, Sarah K., Pham, Tran N., McQueen, Lisa L., Lewandowski, Józef R. and Brown, Steven P. (2020) Revealing intermolecular hydrogen bonding structure and dynamics in a deep eutectic pharmaceutical by magic-angle spinning NMR spectroscopy. Molecular Pharmaceutics, 17 (2). pp. 622-631. doi:10.1021/acs.molpharmaceut.9b01075 ISSN 1543-8384.

Hasan, Muhammad, Patel, Dharmesh, Ellis, Natalie, Brown, Steven P., Lewandowski, Józef R. and Dixon, Ann M. (2019) Modulation of transmembrane domain interactions in neu receptor tyrosine kinase by membrane fluidity and cholesterol. Journal of Membrane Biology, 252 . pp. 357-369. doi:10.1007/s00232-019-00075-4 ISSN 0022-2631.

Kosol, Simone, Gallo, Angelo, Griffiths, Daniel, Valentic, Timothy R., Masschelein, Joleen, Jenner, Matthew, de los Santos, Emmanuel L. C., Manzi, Lucio, Sydor, Paulina K., Rea, Dean, Zhou, Shanshan, Füllöp, Vilmos, Oldham, Neil J., Tsai, Shiou-Chuan, Challis, Gregory L. and Lewandowski, Józef R. (2019) Structural basis for chain release from the enacyloxin polyketide synthase. Nature Chemistry, 11 . 913-923 . doi:10.1038/s41557-019-0335-5 ISSN 1755-4330.

Gallo, Angelo, Franks, W. Trent and Lewandowski, Józef R. (2019) A suite of solid-state NMR experiments to utilize orphaned magnetization for assigning proteins using parallel high and low gamma detection. Journal of Magnetic Resonance, 305 . pp. 219-231. doi:10.1016/j.jmr.2019.07.006 ISSN 1090-7807.

Öster, Carl, Kosol, Simone and Lewandowski, Józef R. (2019) Quantifying microsecond exchange in large protein complexes with accelerated relaxation dispersion experiments in the solid state. Scientific Reports, 9 (11082). 11082 . doi:10.1038/s41598-019-47507-8 ISSN 2045-2322.

Alkhalaf, Lona M., Barry, Sarah M., Rea, Dean, Gallo, Angelo, Griffiths, Daniel, Lewandowski, Józef R., Fülöp, Vilmos and Challis, Gregory L. (2019) Binding of distinct substrate conformations enables hydroxylation of remote sties in thaxtomin D by cytochrome P450 TxtC. Journal of the American Chemical Society, 141 (1). pp. 216-222. doi:10.1021/jacs.8b08864 ISSN 0002-7863.

Öster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G. and Lewandowski, Józef R. (2018) Structural studies suggest aggregation as one of the modes of action for teixobactin. Chemical Science, 9 (47). pp. 8850-8859. doi:10.1039/c8sc03655a ISSN 2041-6520.

Kosol, Simone, Jenner, Matthew, Lewandowski, Józef R. and Challis, Gregory L. (2018) Protein–protein interactions in trans-AT polyketide synthases. Natural Product Reports, 35 (10). pp. 1097-1109. doi:10.1039/C8NP00066B ISSN 0265-0568.

Sternberg, Ulrich, Witter, Raiker, Kuprov, Ilya, Lamley, Jonathan M., Oss, Andres, Lewandowski, Józef R. and Samoson, Ago (2018) 1H line width dependence on MAS speed in solid state NMR – comparison of experiment and simulation. Journal of Magnetic Resonance, 291 . pp. 32-39. doi:10.1016/j.jmr.2018.04.003 ISSN 1090-7807.

Jenner, Matthew, Kosol, Simone, Griffiths, Daniel, Prasongpholchai, Panward, Manzi, Lucio, Barrow, Andrew S., Moses, John E., Oldham, Neil J., Lewandowski, Józef R. and Challis, Gregory L. (2018) Mechanism of intersubunit ketosynthase–dehydratase interaction in polyketide synthases. Nature Chemical Biology, 14 . pp. 270-275. doi:10.1038/nchembio.2549 ISSN 1552-4450.

Öster, Carl, Kosol, Simone, Hartmüller, Christoph, Lamley, Jonathan M., Iuga, Dinu, Oss, Andres, Org, Mai-Liis, Vanatalu, Kalju, Samoson, Ago, Madl, Tobias and Lewandowski, Józef R. (2017) Characterization of protein–protein interfaces in large complexes by solid-state NMR solvent paramagnetic relaxation enhancements. Journal of the American Chemical Society, 139 (35). pp. 12165-12174. doi:10.1021/jacs.7b03875 ISSN 0002-7863.

Good, Daryl B., Pham, Charlie, Jagas, Jacob, Lewandowski, Józef R. and Ladizhansky, Vladimir (2017) Solid-state NMR provides evidence for small-amplitude slow domain motions in a multi-spanning transmembrane α-helical protein. Journal of the American Chemical Society, 139 (27). pp. 9246-9258. doi:10.1021/jacs.7b03974 ISSN 0002-7863.

Hoop, Cody L., Lin, Hsiang-Kai, Kar, Karunakar, Magyarfalvi, Gábor, Lamley, Jonathan M., Boatz, Jennifer C., Mandal, Abhishek , Lewandowski, Józef R., Wetzel, Ronald and van der Wel, Patrick C. A. (2016) Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core. Proceedings of the National Academy of Sciences, 113 (6). pp. 1546-1551. doi:10.1073/pnas.1521933113 ISSN 0027-8424.

Masschelein, Joleen, Sydor, P. K., Griffiths, D. E., Valentic, T. R., Gallo, A., Jones, C., Song, L., Tsai, S. C., Lewandowski, J. R., Mahenthiralingam, E. and Challis, G. L. (2016) Dissection and rational engineering of the biosynthetic pathway to enacyloxin, a promising anti-Gram-negative antibiotic. Planta Medica, 81 (S 01). S1-S381. doi:10.1055/s-0036-1596129 ISSN 0032-0943.

Lamley, Jonathan M., Öster, Carl, Stevens, Rebecca A. and Lewandowski, Józef R. (2015) Intermolecular interactions and protein dynamics by solid-state NMR spectroscopy. Angewandte Chemie International Edition, 54 (51). pp. 15374-15378. doi:10.1002/anie.201509168 ISSN 1433-7851.

Lamley, Jonathan M., Lougher, Matthew J., Sass, Hans Jürgen, Rogowski, Marco, Grzesiek, Stephan and Lewandowski, Józef R. (2015) Unraveling the complexity of protein backbone dynamics with combined 13C and 15N solid-state NMR relaxation measurements. Phys. Chem. Chem. Phys., 17 (34). pp. 21997-22008. doi:10.1039/c5cp03484a ISSN 1463-9076.

Lewandowski, Józef R., Halse, M. E., Blackledge, Martin and Emsley, Lyndon (2015) Direct observation of hierarchical protein dynamics. Science, 348 (6234). pp. 578-581. doi:10.1126/science.aaa6111 ISSN 0036-8075.

Lamley, Jonathan M., Iuga, Dinu, Öster, Carl, Sass, Hans Jürgen, Rogowski, Marco, Oss, Andres, Past, Jaan, Reinhold, Andres, Grzesiek, Stephan, Samoson, Ago and Lewandowski, Józef R. (2014) Solid-state NMR of a protein in a precipitated complex with a full-length antibody. Journal of the American Chemical Society, Volume 136 (Number 48). pp. 16800-16806. doi:10.1021/ja5069992 ISSN 0002-7863.

Good, Daryl B., Wang, Shenlin, Ward, Meaghan E., Struppe, Jochem, Brown, Leonid S., Lewandowski, Józef R. and Ladizhansky, Vladimir (2014) Conformational dynamics of a seven transmembrane helical protein anabaena sensory rhodopsin probed by solid-state NMR. Journal of the American Chemical Society, Volume 136 (Number 7). pp. 2833-2842. doi:10.1021/ja411633w ISSN 0002-7863.

Lewandowski, Józef R. (2013) Advances in solid-state relaxation methodology for probing site-specific protein dynamics. Accounts of Chemical Research, Volume 46 (Number 9). pp. 2018-2027. doi:10.1021/ar300334g ISSN 0001-4842.

Giffard, Mathilde, Hediger, Sabine, Lewandowski, Józef R., Bardet, Michel, Simorre, Jean-Pierre, Griffin, Robert G. and De Paëpe, Gaël (2012) Compensated second-order recoupling : application to third spin assisted recoupling. Physical Chemistry Chemical Physics, Vol.14 (No.20). pp. 7246-7255. doi:10.1039/c2cp40406k ISSN 1463-9076.

Lamley, Jonathan M. and Lewandowski, Józef R. (2012) Simultaneous acquisition of homonuclear and heteronuclear long-distance contacts with time-shared third spin assisted recoupling. Journal of Magnetic Resonance, Volume 218 . pp. 30-34. doi:10.1016/j.jmr.2012.03.013 ISSN 1090-7807.

Lewandowski, Józef R., Sass, Hans Jürgen, Grzesiek, Stephan, Blackledge, Martin and Emsley, Lyndon (2011) Site-specific measurement of slow motions in proteins. Journal of the American Chemical Society, Vol.133 (No.42). pp. 16762-16765. doi:10.1021/ja206815h ISSN 0002-7863.

Lewandowski, Józef R., van der Wel, Patrick C. A., Rigney, Mike, Grigorieff, Nikolaus and Griffin, Robert G. (2011) Structural complexity of a composite amyloid fibril. Journal of the American Chemical Society, Vol.133 (No.37). pp. 14686-14698. doi:10.1021/ja203736z ISSN 0002-7863.

Lewandowski, Józef R., Dumez, Jean-Nicolas, Akbey, Ümit, Lange, Sascha, Emsley, Lyndon and Oschkinat, Hartmut (2011) Enhanced resolution and coherence lifetimes in the solid-state NMR spectroscopy of perdeuterated proteins under ultrafast magic-angle spinning. Journal of Physical Chemistry Letters, Vol.2 (No.17). pp. 2205-2211. doi:10.1021/jz200844n ISSN 1948-7185.

Paëpe, Gaël De, Lewandowski, Józef R., Loquet, Antoine, Eddy, Matt, Megy, Simon, Böckmann, Anja and Griffin, Robert G. (2011) Heteronuclear proton assisted recoupling. The Journal of Chemical Physics, Vol.134 (No.9). 095101. doi:10.1063/1.3541251 ISSN 0021-9606.

Bertini, Ivano, Emsley, Lyndon, Felli, Isabella C., Laage, Ségolène, Lesage, Anne, Lewandowski, Józef R., Marchetti, A. (Alessandro), Pierattelli, Roberta and Pintacuda, Guido (2011) High-resolution and sensitivity through-bond correlations in ultra-fast magic angle spinning (MAS) solid-state NMR. Chemical Science, Vol.2 (No.2). pp. 345-348. doi:10.1039/c0sc00397b ISSN 2041-6520.

van der Wel, Patrick C. A., Lewandowski, Józef R. and Griffin, Robert G. (2010) Structural characterization of GNNQQNY amyloid fibrils by magic angle spinning NMR. Biochemistry, Vol.49 (No.44). pp. 9457-9469. doi:10.1021/bi100077x ISSN 0006-2960.

Lewandowski, Józef R., Sein, Julien, Sass, Hans Jürgen, Grzesiek, Stephan, Blackledge, Martin and Emsley, Lyndon (2010) Measurement of site-specific 13C spin−lattice relaxation in a crystalline protein. Journal of the American Chemical Society, Vol.132 (No.24). pp. 8252-8254. doi:10.1021/ja102744b ISSN 0002-7863.

Barbet-Massin, Emeline, Ricagno, Stefano, Lewandowski, Józef R., Giorgetti, Sofia, Bellotti, Vittorio, Bolognesi, Martino, Emsley, Lyndon and Pintacuda, Guido (2010) Fibrillar vs crystalline full-length β-2-microglobulin studied by high-resolution solid-state NMR spectroscopy. Journal of the American Chemical Society, Vol.132 (No.16). pp. 5556-5557. doi:10.1021/ja1002839 ISSN 0002-7863.

Lewandowski, Józef R., Sein, Julien, Blackledge, Martin and Emsley, Lyndon (2010) Anisotropic collective motion contributes to nuclear spin relaxation in crystalline proteins. Journal of the American Chemical Society, Vol.132 (No.4). pp. 1246-1248. doi:10.1021/ja907067j ISSN 0002-7863.

Bertini, Ivano, Bhaumik, Anusarka, De Paëpe, Gaël, Griffin, Robert G., Lelli, Moreno, Lewandowski, Józef R. and Luchinat, C. (2010) High-resolution solid-state NMR structure of a 17.6 kDa protein. Journal of the American Chemical Society, Vol.132 (No.3). pp. 1032-1040. doi:10.1021/ja906426p ISSN 0002-7863.

Lewandowski, Józef R., Paëpe, Gaël De, Eddy, Matthew T., Struppe, Jochem, Maas, Werner and Griffin, Robert G. (2009) Proton assisted recoupling at high spinning frequencies. Journal of Physical Chemistry B, Vol.113 (No.27). pp. 9062-9069. doi:10.1021/jp810280t ISSN 1520-6106.

Lewandowski, Józef R., Paëpe, Gaël De, Eddy, Matthew T. and Griffin, Robert G. (2009) 15N−15N proton assisted recoupling in magic angle spinning NMR. Journal of the American Chemical Society, Vol.131 (No.16). pp. 5769-5776. doi:10.1021/ja806578y ISSN 0002-7863.

De Paëpe, Gaël, Lewandowski, Józef R., Loquet, Antoine, Böckmann, Anja and Griffin, Robert G. (2008) Proton assisted recoupling and protein structure determination. The Journal of Chemical Physics, Vol.129 (No.24). p. 245101. doi:10.1063/1.3036928 ISSN 0021-9606.

De Paëpe, Gaël, Lewandowski, Józef R. and Griffin, Robert G. (2008) Spin dynamics in the modulation frame : application to homonuclear recoupling in magic angle spinning solid-state NMR. The Journal of Chemical Physics, Vol.128 (No.12). p. 124503. doi:10.1063/1.2834732 ISSN 0021-9606.

Lewandowski, Józef R., De Paëpe, Gaël and Griffin, Robert G. (2007) Proton assisted insensitive nuclei cross polarization. Journal of the American Chemical Society, Vol.129 (No.4). pp. 728-729. doi:10.1021/ja0650394 ISSN 0002-7863.

Dataset

Tognetti, Jacqueline, Franks, W. Trent, Lewandowski, Józef Romuald and Brown, Steven P. (2022) Data for Optimisation of 1H PMLG homonuclear decoupling at 60 kHz MAS to enable 15N-1H through-bond heteronuclear correlation solid-state NMR spectroscopy. [Dataset]

Szell, Patrick M. J., Lewandowski, Józef R., Blade, Helen, Hughes, Leslie P., Lill, Sten O. Nilsson and Brown, Steven P. (2021) Data for Taming the dynamics in a pharmaceutical by cocrystallization: investigating the impact of the coformer by solid-state NMR. [Dataset]

Mann, Sarah K., Devgan, Mohit, Franks, W. Trent, Huband, Steven, Chan, Chi Long, Griffith, Jeraime, Pugh, David, Brooks, Nicholas, Welton, Tom, Pham, Tran N., McQueen, Lisa L., Lewandowski, Józef R. and Brown, Steven P. (2020) Data for MAS NMR investigation of molecular order in an ionic liquid crystal. [Dataset]

Mann, Sarah K., Pham, Tran N., McQueen, Lisa L., Lewandowski, Józef R. and Brown, Steven P. (2020) Data for Revealing intermolecular hydrogen bonding structure and dynamics in a deep eutectic pharmaceutical by magic-angle spinning NMR spectroscopy. [Dataset]

Gallo, Angelo, Franks, W. Trent and Lewandowski, Józef R. (2019) Data for A suite of solid-state NMR experiments to utilize orphaned magnetization for assignment of proteins using parallel high and low gamma detection. [Dataset]

Gallo, Angelo, Franks, W. Trent and Lewandowski, Józef R. (2019) Data for Pulse programs for multiple receiver acquisition. [Dataset]

Kosol, Simone, Gallo, Angelo, Griffiths, Daniel, Valentic, Timothy R., Masschelein, Joleen, Jenner, Matthew, de los Santos, Emmanuel L. C., Manzi, Lucio, Sydor, Paulina K., Rea, Dean, Zhou, Shanshan, Fülöp, Vilmos, Oldham, Neil J., Tsai, Shiou-Chuan, Challis, Gregory L. and Lewandowski, Józef R. (2019) Data for Structural basis for chain release from the enacyloxin polyketide synthase. [Dataset]

Öster, Carl, Lewandowski, Józef R. and Kosol, Simone (2019) Data for Quantifying microsecond exchange in large protein complexes with accelerated relaxation dispersion experiments in the solid state. [Dataset]

Öster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G. and Lewandowski, Józef R. (2018) Data for Structural studies suggest aggregation as one of the modes of action for teixobactin. [Dataset]

Öster, Carl, Kosol, Simone, Hartlmuller, Christoph, Lamley, Jonathan M., Iuga, Dinu, Oss, Andres, Org, Mai-Liis, Vanatalu, Kalju, Samoson, Ago, Madl, Tobias and Lewandowski, Józef R. (2017) Data for Characterization of Protein−Protein Interfaces in Large Complexes by Solid-State NMR Solvent Paramagnetic Relaxation Enhancements. [Dataset]